docj077 said:
Here's the problem that I have with everything that you're saying. In men with male pattern baldness the negative feedback mechanisms that normally govern hormone levels do not seem to be in place.).
They're not being ALLOWED to be put back into place. Its too much for the body to achieve when the diet is working against it.
docj077 said:
This seems to be occurring in the majority of men with male pattern baldness. Whether it be a decrease in SHBG or an increase in IGF-1, the answer can not be with diet. It simply can not be, because if there is a lack of regulation, then the problem is genetic..).
Wrong. Genetics may play some part but it is the diet which governs levels of hormones.
docj077 said:
"Hormonal imbalance" is not something that can be achieved through diet and it is obvious from studies that there is a genetic link as families with men with male pattern baldness have a higher chance of having women with PCOS...).
And it is also known that people from these families have an intolerance for high insulin and its growth like factors. ( i can show you studies if you like).
docj077 said:
That means that the predisposition towards imbalance is inherited. It also means that changing diet can not signficiantly alter hormonal concentrations enough to allow for balance to return.
This is WRONG. PCOS women can return to health via control of their diet. And YES diet CAN alter hormonal concentrations enough.
docj077 said:
That was made very obvious by the differing levels of hormones and SHBG that are observed men with and men without male pattern baldness.
Its not hard to alter SHBG levels. All you have to do is either raise or take down your insulin through diet.
docj077 said:
Any imbalance observed in studies is genetic, the mutation in the androgen receptor is genetic, and male pattern baldness is genetic..
This is merely OPINION. Yes, male pattern baldness has a genetic element just like everything but it is the environment whic provides the triggers.
docj077 said:
Altering environmental factors will not change the outcome as there is nothing that a person can do through diet or exercise that will lower androgens or any other factor enough to prevent or reverse male pattern baldness...
This is inaccurate. Lowering IGF-1 will interfere with the conversion from T to DHT.
docj077 said:
You must remove 65% of the function of 5-alpha reductase type II just to maintain or regrow hair....
This is not strictly true.
docj077 said:
Also, there are no studies that prove that decreasing IGF-1 levels with reverse male pattern baldness or allow men to maintain the hair they have currently.
No but there are studies which state that IGF-1 is at normal levels in non-balding people.
docj077 said:
In a normal man without a defective androgen receptor the increase in IGF-1 in the serum will promote hirsutism..
Exactly - which is a sign of male pattern baldness.
docj077 said:
Decreasing IGF-1 in a man with male pattern baldness won't necessary do just the opposite and their is no evidence in the literature to allow such an assumption...
Well if IGF-1 is the triggering factor then its not such a bad assumption. Moreover, women who have hirutism who reduce IGF-1 actually remove their symtpoms.
docj077 said:
That's why this whole thread is ridiculous and that's why even if there is a shred a truth to this whole thing we're simply wasting time, because trying to change it simply will not help male pattern baldness. ...
I TOTALLY disagree, and so does that guy Immortal Hair who has been researching hair loss since 1998 - longer than either you or I.
docj077 said:
It may help the health of the patient, but it will not stop the action of androgens in the scalp....
Given that IGF-1 is said to create androgens via stimulating 5ar then reducing it would reduce/stop androgens in the scalp.
docj077 said:
IGF-1 will be there no matter what you do....
Yes but we can lower its level and the levels of its co-factors.
docj077 said:
and so will androgens unless you either reduce their potency by only allow testosterone to bind by reducing DHT or you prevent their binding all together by inhibiting the androgen receptor. Anything else is unhealthy. Especially, reducing IGF-1 levels enough to make a difference (which it likely wouldn't anyway).
According to Immortal Hair it will. According to the studies it will. According to Gabe Mirkin M.D. it will and the IGF-1 expert many others.
According to your inferior knowledge it won't. What makes you think you know more? You don't. These guys know their stuff and more research is being carried on in this area.