Italian Hair Loss Lotion To Hit The Market In 2016
- Thread starter paleocapa89
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don't be mad, you're the only italian in this forum (brotzu thread) that we can count on it to bring us news.
Tldr, but I get the gist of it. Histogen fakes their data, and Fidia's lotion is built on a more realistic theory. People think a lot of unnecessary words makes them seem smart, but brevity is better. Anyways, I don't buy your argument. I've been skeptical of Brotzu from day 1 because this theory has already been tried on the forums, and it's not that difficult. It might work as well as minoxidil and finasteride, but it's not going to be an advancement in treatment.
Histogen may have faked their data, but Fidia doesn't even have data, so you're just hanging your hope on a theory that's been tried and failed. Histogen's HSC is actually on very solid theoretical ground, it's basically a supercharged minoxidil, so there's reason to believe that their results are real. Why can't they get funding? Would you rather invest in a supercharged minoxidil or hair multiplication? Fidia has a network already to put this lotion out and make a few bucks with little investment. It's not much of a gamble even if it doesn't work. To invest in a startup like Histogen when RIKEN and others are closing in on a CURE, is quite a bit riskier. Despite that, they have managed to raise significant capital. I'm sure all those millions came from naive people though.
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Tldr, but I get the gist of it. Histogen fakes their data, and Fidia's lotion is built on a more realistic theory. People think a lot of unnecessary words makes them seem smart, but brevity is better. Anyways, I don't buy your argument. I've been skeptical of Brotzu from day 1 because this theory has already been tried on the forums, and it's not that difficult. It might work as well as minoxidil and finasteride, but it's not going to be an advancement in treatment.
Histogen may have faked their data, but Fidia doesn't even have data, so you're just hanging your hope on a theory that's been tried and failed. Histogen's HSC is actually on very solid theoretical ground, it's basically a supercharged minoxidil, so there's reason to believe that their results are real. Why can't they get funding? Would you rather invest in a supercharged minoxidil or hair multiplication? Fidia has a network already to put this lotion out and make a few bucks with little investment. It's not much of a gamble even if it doesn't work. To invest in a startup like Histogen when RIKEN and others are closing in on a CURE, is quite a bit riskier. Despite that, they have managed to raise significant capital. I'm sure all those millions came from naive people though.
First, most venture capital finding fails. That's not a good argument.
Second, if histogen is a supercharged minoxidil, then it doesn't stand on strong theoretical grounds. Nobody actually knows how minoxidil works. Also the DGLA in Brotzu's lotion is thought to be like minoxidil, and nobody's tried it as far as I know.
By the way find me three examples of people who tried topical s-equol with pictures. You say people have tried it ... Well then prove it.
Finally histogen is not claiming to be a super minoxidil so you shouldn't make that claim on their behalf. They're saying that they grow hair at the hairline and temples and that they can make belly's hairs go terminal. We'll see.
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It's definitely impossible to people to test normally an s-equol against Androgenetic Alopecia, as Brotzu explained in all his scientific essays, he demonstrated that DGLA and Equol are unable to penetrate the skin. There came his idea to carry them in liposomes positively charged: the full attachment to the skin is perfectly guaranteed, and then they release the compounds they are carrying (DGLA and Equol, in fact). Applying topically Borraginee Oil or other DGLA sources is uneffective because of this. Then, I highly doubt anyone even tried topically S-Equol, because the cost of the pure compound is TOO MUCH, we are talking about, as a IESON user proved recently, for like 470€ for 100 ml of Brotzu Lotion (can't remember euros for grams, but it's high).
And for those who tried sistemically equol with ingesting large quantities of soia (or horse piss
) , they failed because the quantities of equol are minimal in natural products. It needs to be isolated from large quantities (hence its cost).Then, about DGLA, it was already explained too many times that it is not a powered-up minoxidil: again, minoxidil is a vasodilator which can act only on the perycyte, while DGLA carried in liposomes reaches the endothelial cells, and for all its properties (common to all his evolutive chain which leads to PGE1) can do much more than vasodilating, in fact it repairs blood vessel and causes neoangiogenesis (!!!). Like PGE1, it has a very brief half life if injected, Brotzu talked about 20 minutes. It's nearly impossible without the doctor's strategy or something like that to make these compounds to reach the follicles.
- Reaction score
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It's definitely impossible to people to test normally an s-equol against Androgenetic Alopecia, as Brotzu explained in all his scientific essays, he demonstrated that DGLA and Equol are unable to penetrate the skin. There came his idea to carry them in liposomes positively charged: the full attachment to the skin is perfectly guaranteed, and then they release the compounds they are carrying (DGLA and Equol, in fact). Applying topically Borraginee Oil or other DGLA sources is uneffective because of this. Then, I highly doubt anyone even tried topically S-Equol, because the cost of the pure compound is TOO MUCH, we are talking about, as a IESON user proved recently, for like 470€ for 100 ml of Brotzu Lotion (can't remember euros for grams, but it's high).
And for those who tried sistemically equol with ingesting large quantities of soia (or horse piss
Then, about DGLA, it was already explained too many times that it is not a powered-up minoxidil: again, minoxidil is a vasodilator which can act only on the perycyte, while DGLA carried in liposomes reaches the endothelial cells, and for all its properties (common to all his evolutive chain which leads to PGE1) can do much more than vasodilating, in fact it repairs blood vessel and causes neoangiogenesis (!!!). Like PGE1, it has a very brief half life if injected, Brotzu talked about 20 minutes. It's nearly impossible without the doctor's strategy or something like that to make these compounds to reach the follicles.
View attachment 50400
A convincing post, kudos.
It's definitely impossible to people to test normally an s-equol against Androgenetic Alopecia, as Brotzu explained in all his scientific essays, he demonstrated that DGLA and Equol are unable to penetrate the skin. There came his idea to carry them in liposomes positively charged: the full attachment to the skin is perfectly guaranteed, and then they release the compounds they are carrying (DGLA and Equol, in fact). Applying topically Borraginee Oil or other DGLA sources is uneffective because of this. Then, I highly doubt anyone even tried topically S-Equol, because the cost of the pure compound is TOO MUCH, we are talking about, as a IESON user proved recently, for like 470€ for 100 ml of Brotzu Lotion (can't remember euros for grams, but it's high).
And for those who tried sistemically equol with ingesting large quantities of soia (or horse piss
Then, about DGLA, it was already explained too many times that it is not a powered-up minoxidil: again, minoxidil is a vasodilator which can act only on the perycyte, while DGLA carried in liposomes reaches the endothelial cells, and for all its properties (common to all his evolutive chain which leads to PGE1) can do much more than vasodilating, in fact it repairs blood vessel and causes neoangiogenesis (!!!). Like PGE1, it has a very brief half life if injected, Brotzu talked about 20 minutes. It's nearly impossible without the doctor's strategy or something like that to make these compounds to reach the follicles.View attachment 50400
Well, that's how you represent your point of view!
I don't care about convincing you, so I'm not doing your research. I'm just stating what I think, and I don't speak for Histogen. We don't know how minoxidil works, but there are theories, and Histogen targets one of those more credible theories in a more direct way. Use the search function if you want to find people who tried S-equol, I don't have time to do it for you. Time will tell who is right.
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You're the one claiming that people have tried s-equol. You're saying that we know it doesn't work.
No evidence though.
Ok. Like I said, you will all believe what you want no matter what, I'm not interested in convincing anyone. I have better things to do.
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I will believe the evidence.
When there evidence we will see that I'm right. This thread proves how gullible people are. You could post a theory for why rubbing peanut butter on your head will cure hairloss and people will fall for it. This is just silly. A grain or two of scientific truth and a convoluted theory will confuse and trick people every time.
If you have nothing to say, say nothing at all! If you have better things to do, why even post your inconclusively statement here?
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What is this bullshit? Did a thread EVER got locked? Like.. I know threads get locked if they are solved like in a computer forum.. but in a research forum? Locking a thread here?
I don't get it and I will never get it. Just stop coming here. If people find things to discuss, they discuss. Easy as that.
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profile pic matches perfect hahahaha
MrJolly16
Experienced Member
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Hi! I´ve been reading the IESON forum and it seems Italian people are talking about stability problems, so who can translate a few sentences? Thanks!
I think the lotion works, but it can´t be stored a long period of time just a few weeks. Am I right? What do you think?
nella discussione della ''home made'' alcuni tornano a parlare del fatto che la soluzione non si mantenga. Questo può far pensare che Fidia non potrà mai fare un suo prodotto in esclusiva? Insomma, se devono essere bassi quantitativi di lozione (50ml) che durano poco (2 mesi al massimo?) vuol dire che deve essere fatta su richiesta, quindi sarebbe impraticabile per una casa farmaceutica, o no? Anche perchè a questo punto se funzionasse, qualsiasi farmacia potrebbe farsela da se come galenica, tanto chi va a vedere cosa ci mettono dentro per contestare la violazione del brevetto?
Non credo che Brotzu ne sfornasse in continuazione...secondo me è più probabile che avesse trovato un metodo per conservarle a lungo termine, magari a bassissime temperature...poi quando erano da utilizzare, potevano essere mantenute a temperature maggiori per non più di qualche settimana.
Se fidia non ha raccontato le solite stronzate giusto per coprire la completa inutilità di questo brevetto acquistato, il problema è proprio di STABILITÀ.
Quindi, non credo che si possa sperare che i 100ml durino in efficacia 3/4 mesi.
I think the lotion works, but it can´t be stored a long period of time just a few weeks. Am I right? What do you think?
nella discussione della ''home made'' alcuni tornano a parlare del fatto che la soluzione non si mantenga. Questo può far pensare che Fidia non potrà mai fare un suo prodotto in esclusiva? Insomma, se devono essere bassi quantitativi di lozione (50ml) che durano poco (2 mesi al massimo?) vuol dire che deve essere fatta su richiesta, quindi sarebbe impraticabile per una casa farmaceutica, o no? Anche perchè a questo punto se funzionasse, qualsiasi farmacia potrebbe farsela da se come galenica, tanto chi va a vedere cosa ci mettono dentro per contestare la violazione del brevetto?
Non credo che Brotzu ne sfornasse in continuazione...secondo me è più probabile che avesse trovato un metodo per conservarle a lungo termine, magari a bassissime temperature...poi quando erano da utilizzare, potevano essere mantenute a temperature maggiori per non più di qualche settimana.
Se fidia non ha raccontato le solite stronzate giusto per coprire la completa inutilità di questo brevetto acquistato, il problema è proprio di STABILITÀ.
Quindi, non credo che si possa sperare che i 100ml durino in efficacia 3/4 mesi.
If beps is reading this, he can go f*** himself, and he can ask old man Brotzu to do the same. They f*****g lied telling us young guys don't have to worry anymore, they have liposome sh*t. Young guys just got false hope. Motherfuckers, that's what they are.