- Reaction score
Some individuals have genetic polymorphism causing persistent sides from what I guess
Japanese study shows around 6% sides. If 25% of the people who took finasteride got sides it would be banned long time ago like Vioxx
I wonder to what extend side effects can be mitigated through the administration of TRTActually, 6% or 2% does not mean anything if you don't take age and baseline libido into account.
I did not notice sides on finasteride when I was 30, but noticed when I was 40..my natural libido went down in the meantime, so the DHT lowering effect is felt differently
So if you are young and/or with a strong libido, in most cases you won't notice the drop..but if your libido is low to start with you will suffer more.
I think people are assuming too much about this drug, drugs are not that simple where you can just predict what happens past the trials based on what happened a few months during the trials. Also people seem to be hyper focused on the TAHC numbers even though it's a maintenance drug so its not growing you new hairs, which if you're on these forums you should know by now.
Just remember years back how the "smart" people on these forums where saying CB wouldn't work because you would need some special vehicle or machine to penetrate the scalp.
Thanks for the news...Do you know what percent the Hairloss formula is expected to be? Does this mean we could go to a Dermatologist office today and get a prescription for the acne version, or will it take time for the production to kick in before supply can circulate? (Understand if this isn't known yet)
The most you'll ever gain from a drug like this is some recently gone vellus hairs that they didn't count turning back to terminal. TAHC is probably the most variable method, shedding could easily throw off the numbers, which is part of what the TAHC is anyway.Well, that's what TAHC tells you - whether in the target area you are gaining, maintaining or losing.
What the dosing study showed is that with CB you're steadily gaining until things go haywire. Hell, if you could address whatever causes the 6 month cliff, maybe you'd keep gaining.
TAHC is probably the most variable method, shedding could easily throw off the numbers, which is part of what the TAHC is anyway.
Old news man. It isnt harmless. It affects the HPA axis.CB is not more effective than finasteride. The phase 2 trial for CB was disappointing, as the results declined sharply between six and twelve months. As mentioned already in this thread, they even used a different reference point for the 12 month results than for the 6 month results in a misleading attempt to make the decline between 6 and 12 months appear less drastic than it really was.
Having said this, CB is believed to be side-effect free as it breaks down into a harmless substance once it goes systemic, and so it is a worthwhile option for those who cannot tolerate finasteride due to side-effects.
Yes you're right. Indeed it does affect the HPA axis in some people that use it. Considering this, in addition to the fairly disappointing results from the phase 2 trial, I don't see how there's all that much to get excited about regarding CB to be honest.Old news man. It isnt harmless. It affects the HPA axis.
Old news man. It isnt harmless. It affects the HPA axis.
Do some research and start stacking sh*t. There's some guys on here who are experimenting like crazy and are getting real regrowth.Great, a medication to address the concerns of the 1% of people who get sides from the current treatments.
But is there anything for the 30-40% of guys who can't stop their hair loss with the current treatments? What a waste of time.
Guys - the good news we have been waiting for years ..The First ever side effects free topical anti androgen has been approved by the FDA today for human use- Clascoterone aka CB-01-03
As some knew already, the first application is for acne, in a cream with only 1% BUT this is the exact same molecule as the upcoming hairloss product which works fine for the vast majority, and has no side effects - unlike RU58841 and the rest of the current drugs finasteride/dutasteride .
I bought the powder from Kane
I mix with ethanol 95% - Polmos rectified spiritus sold in liquor stores, that's all.
no need for dermaroller IMO
You can increase scalp porosity by using more ethanolic topicals, I also use minoxidil and Neogenic in separate applications throughout the day
I use about 50 to 70mg CB a day