Exploring The Hormonal Route. Hair=life.

[keepcoolmybabies]

Won’t a significant portion of that T aromatize in women?




I used to lean towards this theory but when you consider that pseudohermaphrodites (lacking 5AR) never lose hair it makes me believe that the dutasteride hair loss could have to do with upregulation. But perhaps it is a combination. Hmm…

T can be aromatized to E in either sex, and bica generally increases E lvls in cis men taking bica alone. But that increase in T won't occur in cis women (or trans women using E due to its antigonadotropin effect causing negative feedback on the hpg axis).


As for T causing hairloss, I'm honestly not sure. Your point about 5ar deficient individuals being immune to hairloss is valid and made me believe at one time dht was the only potential cause. But I'm really not sure one way or another. I suppose dutasteride could be increasing receptor sensitivity of starved receptors upregulating to such a degree that even a minor amount of dht is potent enough to decimate hair in such unlucky individuals. But who knows ultimately

 

[Almas_NW0]

Without fertility you are not man

This assertion is not supported by anything. It's nothing more than your imagination. In Russia, some say that one who has not served in the army is not a man. You are spouting similar nonsense, which is based on nothing. I don't think a man is defined by his fertility and erection lol
And I don't understand fertility concerns from those who aren't even planning to have children. In my opinion, such contradictory is a sign of dementia.

 

[Guru0007]

This assertion is not supported by anything. It's nothing more than your imagination. In Russia, some say that one who has not served in the army is not a man. You are spouting similar nonsense, which is based on nothing. I don't think a man is defined by his fertility and erection lol

Hey... How is ur hair?.. Treatment working?

 

[Almas_NW0]

Hey... How is ur hair?.. Treatment working?

Yes, I have terminal hair along the Norwood 0 growth line. But it is very thin. I'm waiting for the thickening.

 

[Guru0007]

Yes, I have terminal hair along the Norwood 0 growth line. But it is very thin. I'm waiting for the thickening.

Ur regime?.. I'm currently on 100 mg spironolactone and 4mg estradiol sublingual...

 

[Guru0007]

Ur regime?.. I'm currently on 100 mg spironolactone and 4mg estradiol sublingual...

But since starting hrt... My hair has become brittle and wirey... Is it due to hormonal fluctuations?

 

[Almas_NW0]

Ur regime?.. I'm currently on 100 mg spironolactone and 4mg estradiol sublingual...

Click on "My regimen"
I did not have increased fragility

 

[Guru0007]

Click on "My regimen"
I did not have increased fragility

Ok ... I don't know y my hair turned fragile overnight...

 

[MylovelyHair]

But you will be ready for the balkan summer!!did your doctor say after how many days do you hit the gym??Also can you use via gra together with oral minoxidil?

 

[WendyPayne]

Happy for all of those who succeed to solve the problem, hope that soon I will be among you.

 

[Experimentality]

My biggest mistake I did was to try estrogen, nothing came good out of it as non trans person. I got worse/thinner skin,no regrowth whatsoever,sunken in cheeks like meth addict,shrunken balls (1/4 of original size, now reversed),no muscles,big f*****g tits which im gonna get surgery for in next few days and no energy/depression with 0 libido… theres more probably this were first ones to come up to my mind.
If anyone wants to try HRT “safely” they can just try Bicalutamide high dose monotherapy (with dutasteride), its same effect just much safer (for balls) if you monitor liver enzymes. You would get e2 to lower end of premenopausal women and testosterone activation to women levels. If you dont regrow hair in that environment its very likely full hrt would not benefit you much more. And whats the point in regrowing hair on 8mg E2 when you cant ever come off of that dose. Would rather be bald or dead than to fully commit to trans regimen for life as cis.

Spot on. When someone feels adventurous about oral regimens they should first think very hard, and when still feeling adventurous they could maybe try Bicalutamide (after giving Dutasteride sufficient time, of course). Bicalutamide is still relatively benign (in comparison to E2) since it doesn't actually shut down the HPT axis. The effects of Bicalutamide are also (almost) always reversible, which makes a wrong decision more forgiving. Don't mess with E2 when you're male. I'm 100% sure it will be regretted (genuine trans people are an exception, of course).

 

[cetm-419]

Spot on. When someone feels adventurous about oral regimens they should first think very hard, and when still feeling adventurous they could maybe try Bicalutamide (after giving Dutasteride sufficient time, of course). Bicalutamide is still relatively benign (in comparison to E2) since it doesn't actually shut down the HPT axis. The effects of Bicalutamide are also (almost) always reversible, which makes a wrong decision more forgiving. Don't mess with E2 when you're male. I'm 100% sure it will be regretted (genuine trans people are an exception, of course).

speaking in absolutes is irresponsible, how could you be 100% sure someone will regret anything.

 

[Almas_NW0]

Don't mess with E2 when you're male. I'm 100% sure it will be regretted (genuine trans people are an exception, of course).

I have not seen a single example where someone would regret it. The side effects of HRT are overrated, not underestimated, which is why we don't see people who would regret. The fact is that people are well aware of the side effects and resort to it when it becomes clear that the second choice is the complete destruction of life due to baldness. No one thinks that HRT has no consequences, so they are not horrified when they get changes.
When the question is between HRT and the destruction of life, you are unlikely to regret

 

[RStGeorge]

I have not seen a single example where someone would regret it. The side effects of HRT are overrated, not underestimated, which is why we don't see people who would regret. The fact is that people are well aware of the side effects and resort to it when it becomes clear that the second choice is the complete destruction of life due to baldness. No one thinks that HRT has no consequences, so they are not horrified when they get changes.
When the question is between HRT and the destruction of life, you are unlikely to regret

My only negative side-effect with E2 do far has been gyno.

However, since I started taking 5mg of oral Melatonin my gyno has totally resolved

 

[Almas_NW0]

My only negative side-effect with E2 do far has been gyno.

I can say the same

However, since I started taking 5mg of oral Melatonin my gyno has totally resolved

Never heard of it. Melatonin does not cure gynecomastia and can cause it, how is that possible?

 

[RStGeorge]

I can say the same

Never heard of it. Melatonin does not cure gynecomastia and can cause it, how is that possible?

It DEFINITELY worked for me!
Check this link:

https://www.reddit.com/r/HairlossResearch/comments/qmb9fa

 

[Almas_NW0]

It DEFINITELY worked for me!
Check this link:

https://www.reddit.com/r/HairlossResearch/comments/qmb9fa

My gland was formed while taking Bicalutamide more than six months ago and was already clearly fibrosing, so I was clearly too late

 

[RStGeorge]

My gland was formed while taking Bicalutamide more than six months ago and was already clearly fibrosing, so I was clearly too late

I had gland growth too.

Not only did my breasts look feminised, but my glad was obvious when I would touch it, and it was very painful.

But it is now gone

 

[Almas_NW0]

Im right here boi.

-deleted-
since this is actually trans forum now when I think about it.

I don't know what the Cialis drinker was hoping for when he decided to try HRT. Probably, so masculine and caring about erection and fertility males should not go further than Finasteride. I hope you at least plan to have kids otherwise it's ridiculous

 

[Almas_NW0]

Transboi