I wouldn't rely much on bicalutamide. I've used it non stop for almost a year with dutasteride. Only thing i got is gyno and sore nipples for a year. And then when i shared my experience here, everyone told me bica alone wouldn't do much, you have to take it with estrogen. What's the point of taking bica, if i am to use estrogen ? Anything with estrogen obviously will work good.
My sebum production was unchanged while i was using bicalutamide. I was oily as sh*t like usual. Now I've been taking cpa for 2 months and after like first pill, no more oily nose and face, no more testicle smell. Even after 2 months i still have no sings of gyno or nipple pain.
Even my grandfather's psa levels raised after sometime with bica. It went to 3s and the doctor told him to switch cpa. After that it decreased to below 1.
Obviously everyone is different and you can't know for sure without trying it but i think its obvious that cpa is far more superior than bica. The only problem is its possible long term side effects.