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Exploring The Hormonal Route. Hair=life.

Discussion in 'Success Stories' started by bridgeburn, Oct 27, 2017.

  1. I'mme

    I'mme Experienced Member My Regimen

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    I would like to see your before and after pics. Should you upload them, I'd be grateful.
     
  2. Ikarus

    Ikarus Senior Member My Regimen

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    I don't even think that's a last option! Personally, my last options are: lupron, surgical castration, high-dose of estradiol.

    With his regimen, he might end up with up-regulation if he stops.
     
  3. baba_yaga

    baba_yaga Established Member My Regimen

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    I based my response as the last option on the thought that this regimen makes a man loose his manhood for ever. If thats not the case, I would consider it as any other regimen, but of course I'll try the much less "extreme" ones first, so I would have something stronger to try if a regimen does not have results for me.
     
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  4. DHTcel

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  5. baba_yaga

    baba_yaga Established Member My Regimen

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    Impressive informative thread. It warms my heart when I see people posting genuine info and research so they could help others. I'll give it time later for better inspection, but I guess you are on the right track of stopping this disease. Good luck.
     
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  6. DHTcel

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    yes, thanks!

    its a really bad idea to take (SAA) cyproterone/spironolactone in combination with (NSAA) flutamide / bicalutamide

    this is because SAA's are derivatives of progesterone and therefore have the ability to induce androgenicity

    its good I dropped cpa today, (I was only on it for 12 days) lets see how bica + dutasteride does.
     
  7. revivemycurls

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  8. DHTcel

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    I don't take cpa because it is a partial agonist of the ar, I don't take estradiol because I want to stay male, I don't take oral min because I don't want to look like a bloated water buffalo. Bica + dutas + topical minoxidil is all I take and a little raloxifene to reduce/prevent gyno
     
  9. revivemycurls

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    wikipedia says:
    Bicalutamide, sold under the brand name Casodexamong others, is an antiandrogen medication that is primarily used to treat prostate cancer.[11] It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat advanced prostate cancer.[12][11][13]Bicalutamide may also be used to treat excessive hair growth in women,[14] as a component of feminizing hormone therapy for transgender women,[15] to treat early puberty in boys,[16] and to prevent overly long-lasting erections in men.[17] It is taken by mouth.[11]

    so doesnt bica affect masculanity too? not to mention the erection side it could have...how has it been for you?
     
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  10. DHTcel

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    again, the only feminizing side effect of bicalutamide is gynecomastia and reduction in body hair. It doesn't effect bone mineral density nor muscle mass. Its a gonaditropen and not an antigonaditropen. It also has antiprogesteronic effects and does not act as a steroidal anti androgen.

    as for libido,
    "Another large study reported a rate of impotence of only 9.3% with bicalutamide relative to 6.5% for standard care (the controls), a rate of decreased libido of only 3.6% with bicalutamide relative to 1.2% for standard care, and a rate of 9.2% with bicalutamide for hot flashes relative to 5.4% for standard care.[126] One other study reported decreased libido, impotence, and hot flashes in only 3.8%, 16.9%, and 3.1% of bicalutamide-treated patients, respectively, relative to 1.3%, 7.1%, and 3.6% for placebo.[127] It has been proposed that due to the lower relative effect of NSAAs on sexual interest and activity, with two-thirds of advanced mPC patients treated with them retaining sexual interest, these drugs may result in improved quality of life and thus be preferable for those who wish to retain sexual interest and function relative to other antiandrogen therapies in prostate cancer."

    hope this helps bro
     
  11. LEXUS

    LEXUS Established Member My Regimen

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    Frankly, I do not understand what the problem is. no one has yet died from such regimes. The fact is that all these drugs are of different actions. each works in its own way. I do not even exceed the recommended rate. for example, flutamide can be taken 3 times a day at 250 mg. Cyproterone maximum permitted dose is generally 400 mg. in fact, I did not add recommendations that are allowed. in the future, I am going to reduce cyproterone to 25 mg of bicalutamide to 50 mg and flutamide to 250 mg. but testosterone must be at the feminine level for feminization. I still have it.
     
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  12. LEXUS

    LEXUS Established Member My Regimen

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    when you really want your hair you are ready to go for anything.
     
  13. DHTcel

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    you do realize that using cyproterone/spironolactone in combination with an NSAA basically renders them (bica/flut) useless right?

    "All medically used SAAs are weak partial agonists of the AR rather than silent antagonists, and for this reason, possess inherent androgenicity in addition to their predominantly antiandrogenic actions.[75][76][77] In accordance, although CPA produces feminization of and ambiguous genitalia in male fetuses when administered to pregnant animals,[90] it has been found to produce masculinization of the genitalia of female fetuses of pregnant animals.[76] Additionally, all SAAs, including CPA and spironolactone, have been found to stimulate and significantly accelerate the growth of androgen-sensitive tumors in the absence of androgens, whereas NSAAs like flutamide have no effect and can in fact antagonize the stimulation caused by SAAs.[76][77][91] Accordingly, unlike NSAAs, the addition of CPA to castration has never been found in any controlled study to prolong survival in prostate cancer to a greater extent than castration alone.[76] In fact, a meta-analysis found that the addition of CPA to castration actually reduces the long-term effectiveness of ADT and causes an increase in mortality (mainly due to cardiovascular complications induced by CPA).[92] Also, there are two case reports of spironolactone actually accelerating progression of metastatic prostate cancer in castrated men treated with it for heart failure, and for this reason, spironolactone has been regarded as contraindicated in patients with prostate cancer.[93][94] Because of their intrinsic capacity to activate the AR, SAAs are incapable of maximally depriving the body of androgen signaling, and will always maintain at least some degree of AR activation.[77][91]"

    hope this helped
     
  14. I'mme

    I'mme Experienced Member My Regimen

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    Can this bloating be reduced by eating bananas (=taking more potassium)? People who take MK667 take bananas to reduce water retention.
     
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  15. DHTcel

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    probably, I took mk677 for 2 months for height (I grew half an inch) and I was definitely bloated. potassium offsets sodium so you are right
     
  16. revivemycurls

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    Hey bridge, I am still reading up facts on net before I take the plunge. So I came up with this:

    https://www.cancerresearchuk.org/ab...al/treatment/hormone-therapy/side-effects-men

    Check the section about bone changes which says "There is evidence that the risk of problems such as bone fractures is slightly higher for men having long term treatment to block testosterone"
     
  17. I'mme

    I'mme Experienced Member My Regimen

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    f***, I'm like 5'8 or 5'9 only. Way above average Indian height (5'1 for males, 5'5 as per some measures), but if I could grow 2-3 inches, I would love me more.

    But to increase height you've to do exactly opposite of what you'd do to save hair. Man, my life is so fucked up at this point - I know how to achieve what I want, but I can't.

    Anyway, thank you buddy. If I get 80% density with big3, I'm definitely gonna try mk667.(along with some others - definitely not letrozole though; hair=life :p)
     
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  18. DHTcel

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    im 5foot8 right now, but if you take cpa for example, that lowers LH which then lowers T and E. anything that lowers T/LH in men or T/E in women will make them taller. Letrozole wouldn't make you taller because it doubles on LH secretion and T levels. The studies of height and letrozole is with female mice.
     
  19. I'mme

    I'mme Experienced Member My Regimen

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    What are you saying, DHTcel? The standard treatment includes HGH, MK667, letrozole, MSM among others. Three of which increases testosterone. So can we not say that to increase height we need to increase test and reduce (or demolish) estrogen? (BTW, not gonna do it ; love my hair more)
     
  20. DHTcel

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    HGH and mk677 increase Growth hormone and have no effect on testosterone levels or estrogen levels.
     

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