NorwoodGuardian
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Do you think over 1600 holes will have bad effect?
Very Impressive Dermarolling And Minxodil Results - From Tressless
Do you think over 1600 holes will have bad effect?
If I had to guess, I'd say they stopped at 1600 holes because it wasn't practical to keep trying to add more.
Try drawing 1600 little dots on a square centimeter of paper. You realize that's A TON of holes in a tiny space. It's effectively carpet-bombing the area. And pushing needles into skin is not as precise as making dots on paper with an inkpen. The skin is softer. After a certain point the needles will just be landing back into previous holes.
That tipping point will be different for different individuals but you get the idea. To do clinical trials they had to decide on a specific number and stick with it.
For our experimenting purposes, I really doubt it would cause any harm to overshoot past 1600. Dermabrasion does more damage than any amount of poking holes, and even that is not harmful with adequate recovery time afterwards. Just use common sense.
Try drawing 1600 little dots on a square centimeter of paper. You realize that's A TON of holes in a tiny space. It's effectively carpet-bombing the area. And pushing needles into skin is not as precise as making dots on paper with an inkpen. The skin is softer. After a certain point the needles will just be landing back into previous holes.
That tipping point will be different for different individuals but you get the idea. To do clinical trials they had to decide on a specific number and stick with it.
For our experimenting purposes, I really doubt it would cause any harm to overshoot past 1600. Dermabrasion does more damage than any amount of poking holes, and even that is not harmful with adequate recovery time afterwards. Just use common sense.
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Can you even get scarring from needling at depths 2.0 mm and under? I think I read that in another thread, but I may be wrong. I needle pretty thoroughly at 1.75mm weekly, and hope I haven't screwed myself.
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been using finasteride by 5 and a half years, romaine for 6 years before I added needling weekly at 1.5mm with Dr. Pen 6 months ago. Has done nothing lol, but romaine never worked for me anyway. Starting to think about a hair transplant as I approach 24 and have maintained for almost 7 years now
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Love you signature
Two things that bother me:
- No control group in the study, so there's no way to see whether all the heavy lifting was done by minoxidil (nonetheless, the study's results are quite impressive - improvement by one integer in just four months on the scale is pretty good)
- The fact I still don't manage to get any results microneedling. I am much less strict about my regimen that I used to be in the first 9 months, but I still needle occasionally, imitating the Follica protocol as closely as possible. All this time, no positive changes.
I am wondering if maybe the parameters in the Follica patent for the "one specific embodiment" they always quote are, actually, a ruse. The patent covers a lot of parameter configurations. While it often singles out one specific set of parameters (see my thread on the patent), maybe a different set is actually the real deal?
- No control group in the study, so there's no way to see whether all the heavy lifting was done by minoxidil (nonetheless, the study's results are quite impressive - improvement by one integer in just four months on the scale is pretty good)
- The fact I still don't manage to get any results microneedling. I am much less strict about my regimen that I used to be in the first 9 months, but I still needle occasionally, imitating the Follica protocol as closely as possible. All this time, no positive changes.
I am wondering if maybe the parameters in the Follica patent for the "one specific embodiment" they always quote are, actually, a ruse. The patent covers a lot of parameter configurations. While it often singles out one specific set of parameters (see my thread on the patent), maybe a different set is actually the real deal?
The women were on treatment previously for at least six months. If they were on treatment for exactly six months then the improvement could be a result of minoxidil alone. If they were on minoxidil for 12 months already before starting treatment then their gains would already be maxed out, and any further improvement could be assumed to be from microneedling.
It won't be long before we get the phase 3 results, we should know more then. I don't think it's a ruse, the patent is written to protect their method, not to hide it. Some people just aren't going to respond. Maybe your levels of sulfotransferase are too low, or maybe your hair loss is too aggressive.
It won't be long before we get the phase 3 results, we should know more then. I don't think it's a ruse, the patent is written to protect their method, not to hide it. Some people just aren't going to respond. Maybe your levels of sulfotransferase are too low, or maybe your hair loss is too aggressive.
Phase 3 is supposed to start in 2021. That would mean that starting in December 2021 would still be on schedule. Average duration for phase 3 trials is IIRC 24 months. Then results need to be evaluated and analyzed to prepare the FDA application; these data would then be published as well, probably. That's still almost 3 years from now, assuming a start in the second half of 2021 and average phase 3 trial duration.
Phase 3 should be starting any moment. They aren't using a new drug so I suspect it will only be 12 months, but we'll know soon enough. We'll probably find out more when they begin too, so that could be any day now. I think we'll get topline data in early 2022, and we may even find out more about the protocol when they begin the trial. Let's have some optimism on here for once, Follica is moving along quickly unlike other companies.
Will "official" Dr Pen cartridge fit eBay's one? Needles on my replacement cartridge are completely bent, I guess it is dangerous to use them.
NorwoodGuardian
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How bent is it? Can clearly see from naked eyes? I buy from an Australia website but the price is higher.
NorwoodGuardian
Established Member
- Reaction score
- 184
How much per catridge?