The Cb (breezula [clascoterone]) Community Thread | Page 65 | HairLossTalk Forums

The Cb (breezula [clascoterone]) Community Thread

Discussion in 'New Research, Studies, and Technologies' started by Screeech, Jun 25, 2019.

  1. NotInmywatch

    NotInmywatch Experienced Member My Regimen

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    cb none
    finasteride: penis constant pain, noticeable reduction in girth, watery semen, testicles contracted at maximum and up to the pelvic region, no morning wood

    I don't think that finasteride is a poison per se. BUT if you don't have optimal nutrition, with constant intake of testosterone boosting food and supplements, you could get yourself in some serious trouble.
     
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  2. John Difool

    John Difool Senior Member My Regimen

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    Any sides from broccoli?
     
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  3. karatekid

    karatekid Experienced Member My Regimen

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    Ye he started to piss from his left ear
     
  4. blub10

    blub10 Established Member My Regimen

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    Well you had then weak finasteride sides, if they could be tackeled so easily then the PFS Flrum would be already dead. But thx for the review
     
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  5. tomJ

    tomJ Senior Member My Regimen

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    Thanks for replying...can youbtell us how you made your cb? What did you minoxidil it with and what ratio? How long did it take for the cb to start to slow down the shedding? Was it immediate? Was your scalp less oily on cb and if so how long did it take for that to occur? Thanks again
     
  6. tomJ

    tomJ Senior Member My Regimen

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    Anyone else have cb experience?
     
  7. bucksins6x

    bucksins6x Established Member My Regimen

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    From what I’ve heard. It only works for a year max and that’s at a high dose. Maybe I’m wrong
     
  8. tomJ

    tomJ Senior Member My Regimen

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    Thanks for responding. We will see if others chime in?
     
  9. tomJ

    tomJ Senior Member My Regimen

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    Any results?
     
  10. Jim lahey

    Jim lahey Established Member My Regimen

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    Where'd you hear that from
     
  11. John Difool

    John Difool Senior Member My Regimen

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    It's not specifically CB that stops working over time. It's more the fact that any topical AA will need a higher dosage after some time to keep working. Even RU will. The issue with CB is that you already start at 7.5% which is a high dosage and cost more than RU at 5%. With the price of RU no prob doubling the dosage overtime. CB is much less affordable in that case and for the extra cost it has yet to demonstrate a better maintenance factor than other AA.

    I like RU. I call it the topical Bicalutamide.
     
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  12. Dimitri001

    Dimitri001 Established Member My Regimen

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    The graph on page 62 of this thread shows it.

    I wonder whether cycling off and back on it might not help, as someone suggested.
     
  13. John Difool

    John Difool Senior Member My Regimen

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    Cycling off will lose the maintenance that you will need to recover by cycling in and as we know it's harder each time. If it was that simple folks on Fina would do the same over a decade but that's not how it works.
     
  14. Dimitri001

    Dimitri001 Established Member My Regimen

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    Who knows, maybe what you lose while off it is less than you gain while on it. If you look at the graph, they weren't just maintaining, they were gaining. Say you go off 6 months in, when you've hit peak and then you go on some time later... who knows.

    In fact, and I have no idea how these things work, so I may be talking nonsense, but if the idea is that the androgen receptor becomes desensitized to the effect of CB, what if you were to go off CB right before that desensitization happens? We see in the graph that up to month 6 it's a steady gain and then it drops off after that. So what if you were to briefly go off it before this. Would the desensitization not happen and you can go back on it quickly?

    Well, fina works through a different mechanism so the problem we're talking about here doesn't even enter into the equation with fina.
     
    #1294 Dimitri001, Jul 16, 2020
    Last edited: Jul 16, 2020
  15. John Difool

    John Difool Senior Member My Regimen

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    I think they were gaining compare to people who were losing hair on placebo not gaining from baseline.

    Of course it does. Building resistance to drugs is what makes a treatment very difficult to continue over time. There is a time bounded limit for any treatment and less effectiveness after some time. I have personal experience with this unfortunately.
     
  16. Dimitri001

    Dimitri001 Established Member My Regimen

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    No, the 0 in the graph is the baseline. Placebo is on the far right
     
  17. John Difool

    John Difool Senior Member My Regimen

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    Let's see what phase 3 brings us
     
  18. pegasus2

    pegasus2 Senior Member My Regimen

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    If you're using it as a monotherapy cycling is pointless. If you cycle off topical AA's you need to be on finasteride
     
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  19. Dimitri001

    Dimitri001 Established Member My Regimen

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    Why? If you're on it for 6 months and get the gains the graph shows, then you go off for a month and go back on, at the end of 7 months you may still be at a net gain, no?
     
  20. pegasus2

    pegasus2 Senior Member My Regimen

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    Consider that studies show minoxidil gains are significantly lost in one month. I see no reason to believe this would be any different, and would one month off of it be enough? I think those looking for a miracle without the potential for side effects better shave their heads and start saving for Tsuji.
     

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