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It needed for me only a couple of years (2-5 years).
Stemson is going to use minipigs in the next stage of their hair cloning research
- Thread starter werefckd
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inmyhead
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17 year old and already senior member on hair loss talk with 1.7k messages lol.... Sad
What are you taking? I'm guessing no finasteride yet right?
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I do, read my regimen.
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I tried to analyze yesterday a few interviews of them and Alexey said in one to the Interviewer that it needs to be re-done every 10-15 years, because the hair loss (may) continue. Not sure if he is reffering to the native follicles, which are susceptible to hormones (especially androgens), or the de novo follicles -> the Fortunis guy said that the follicles wouldn't bald again, and would stay most likely permanent, and if this is true then we know to what Dr. Alexey Terskikh was reffering to... (We shouldn't forget that the investor company can make any claim they want) the fact that the native hair continues to fall out (till it reaches the NW7/occipital area), but the new follicles would just then replace every 10-15 years those bald/thinning areas.
If this is true, then thats another breakthrough; achieving the same gene expression of the follicles like the occipital one's have. This would be highly effective for Androgenetic Alopecia.
But it's still up in the horizon, if all this even works on humans, and I can't find any evidence in their papers that they try to make them hormone-insensible.
Another thing I found is, that Antonella Pinto said in the showcase of their tech on a congress in 2019... that they achieved; "some hair to grow out", of the mice. *ONLY SOME*...
I wonder what's the succes rate of the follicles, surviving, cycling and behaving like a healthy one...
If Tsuji's succes rate is translateable to Stemson's method, this would be outrageous.
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Ni
But by Alexey's answer; "making a lifelong unlimited supply of follicles", I understand that they think; the de novo follicles indeed continue to miniaturize due to Androgenetic Alopecia.
Nice find! A shame all those Interviewers never ask what the stemson team thinks of their approach in terms of Androgenetic Alopecia.Medical Research: What should clinicians and patients take away from your report?
Dr. Terskikh: We are still at early stages. Our next steps are to optimize the cell preparation procedure. And most importantly, we need to perform transplantation experiments using human skin (human volunteers) to assure the clinical usefulness of this procedure.
Lab Turns Stem Cells Into Hair Bulbs That Grow Hair
MedicalResearch.com Interview with: Alexey Terskikh, Ph.D. Associate Professor Department of Developmental and Stem Cell Biology Sanford-Burnham Medical Resmedicalresearch.com
Interview from 2021.
But by Alexey's answer; "making a lifelong unlimited supply of follicles", I understand that they think; the de novo follicles indeed continue to miniaturize due to Androgenetic Alopecia.
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It sounds like they are still trying to understand the differentiation mechanism using neural crest cells, and finding the most efficient ways to produce/store in vitro hair follicle.Medical Research: What should clinicians and patients take away from your report?
Dr. Terskikh: We are still at early stages. Our next steps are to optimize the cell preparation procedure. And most importantly, we need to perform transplantation experiments using human skin (human volunteers) to assure the clinical usefulness of this procedure.
Lab Turns Stem Cells Into Hair Bulbs That Grow Hair
MedicalResearch.com Interview with: Alexey Terskikh, Ph.D. Associate Professor Department of Developmental and Stem Cell Biology Sanford-Burnham Medical Res
Interview from 2021.
That's from January 2015: "MedicalResearch.com Interview with, & Alexey Terskikh, Ph.D. (2015). Lab Turns Stem Cells Into Hair Bulbs That Grow Hair MedicalResearch.com"Medical Research: What should clinicians and patients take away from your report?
Dr. Terskikh: We are still at early stages. Our next steps are to optimize the cell preparation procedure. And most importantly, we need to perform transplantation experiments using human skin (human volunteers) to assure the clinical usefulness of this procedure.
Lab Turns Stem Cells Into Hair Bulbs That Grow Hair
MedicalResearch.com Interview with: Alexey Terskikh, Ph.D. Associate Professor Department of Developmental and Stem Cell Biology Sanford-Burnham Medical Res
Interview from 2021.
Yeah, I was going to say, they already passed the cell preparation step years ago.
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"Hot off the press as of today in Current Protocols. A great collaboration between Cellino and Stemson Therapeutics to capture the incredible work happening in this industry, and looking forward to what's next."
www.linkedin.com
The guy on here who predicted their collaboration is such a freak lmao, good prediction, you were right!
Was it @werefckd ?
Cellino on LinkedIn: Please read: "Autologous Induced Pluripotent Stem Cell–Based Cell…
Please read: "Autologous Induced Pluripotent Stem Cell–Based Cell Therapies: Promise, Progress, and Challenges" written by Marinna Madrid, PhD, Cenk Sumen…
The guy on here who predicted their collaboration is such a freak lmao, good prediction, you were right!
Was it @werefckd ?
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Isn't that basically a study on the current state where an employee of Stemson was involved? I mean it surely means they are in contact but doesn't look like much more. It's always good to see any kind of update though.
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What does preparing for IND mean? It says that under the stage for stemsontx"Hot off the press as of today in Current Protocols. A great collaboration between Cellino and Stemson Therapeutics to capture the incredible work happening in this industry, and looking forward to what's next."
Cellino on LinkedIn: Please read: "Autologous Induced Pluripotent Stem Cell–Based Cell…
Please read: "Autologous Induced Pluripotent Stem Cell–Based Cell Therapies: Promise, Progress, and Challenges" written by Marinna Madrid, PhD, Cenk Sumen…
The guy on here who predicted their collaboration is such a freak lmao, good prediction, you were right!
Was it @werefckd ?
“Mouse studies published, preparing for IND”
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No. This clearly shows us that Stemson collabroates now with Cellino. Cellini developed a technology to multiplay iPSc and many other cells for a little price in a short period of time. This is a huge step for me! It would lower the cost a bunch if I had to guess.
Also, is it true that they can take skin samples from the occipital area!?
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The IND application is submitted by the company or research group responsible for developing the drug to the FDA. The FDA reviews IND applications and decides whether they are safe for companies to progress to the clinical trial stage.
But basically every company is doing that, doesn't mean much..
But basically every company is doing that, doesn't mean much..
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Oh, so "investigational new drug"? Lol. FDA will do sh*t for them... F