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Post Finasteride Syndrome: A Broad Overview Of This Devastating Disease

Discussion in 'Men's General Hair Loss Discussions' started by ZZmop, Jul 16, 2019.

  1. heyhey

    heyhey Established Member My Regimen

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    Why do you think DHT is a important hormone? it is a hormone that is used by the body mainly during puberty and childhood, later on in life its basically just a trash hormone. Researchers have not found one vital important role of DHT in the adult male body.

    And why wouldnt i keep taking finasteride? i have not experienced a single side effect except great hair.
     
  2. INT

    INT Senior Member

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    Finasteride reduces 5 AR which has neurological functions
     
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  3. INT

    INT Senior Member

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    Ever heard of Vioxx? Another medicine from Merck. 1000s of subjects showed that it was a totally safe medicine. Until it wasn't... And people started dying.

    I am a published researcher myself and I can tell you; the scientific method is probably the best thing we have at the moment, but is far FAR from being flawless and should always ALWAYS continue to be approached with a critical mind.
     
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  4. heyhey

    heyhey Established Member My Regimen

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    The difference is that it was proved to have long term usage risks easily after just 5 years on the market. Finasteride have not shown any such evidence after over 20 years on the market (even longer for prostate issues).

    The thing that drives this is that people read horror stories online and suddenly they experience a very strong placebo effect while starting the drug. The later studies have shown this to be very true since the placebo group have almost the same percentage of sides as the finasteride group. You have people on the internet claiming to have becomed pfs zombies by eating one finasteride pill.....
     
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  5. heyhey

    heyhey Established Member My Regimen

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    Just because something is found in the brain does not mean it have a vital positive function there. There are a people in the dominican republic who lack any 5 AR at all in their body. They dont have any neurological problems, the only difference between them and us is that they dont experience a good sexual organ development in their puberty and they have great hair. Which further confirms that DHT have a very very limited role in males outside of sexual development during childhood.
     
  6. Armando Jose

    Armando Jose Senior Member My Regimen

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    I think that most people are good guys,....
    Taking in account that finas dont make miracles in common hair loss,
     
  7. Armando Jose

    Armando Jose Senior Member My Regimen

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    IMHO its a lie, impossible for life if you have not any of the 3 types of 5AR´s, no compatible with life,

    Have you any study?
     
  8. BadInvertor

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    Omfg it's like you guys have not heard of Google.

    "Children with the condition are genetically male, meaning they have one X and one Y chromosome. However, as they develop in the womb, a genetic mutation prevents their bodies from converting the male hormone testosterone into a hormone called dihydrotestosterone, or DHT. Because DHT is responsible for the development of male sex organs, the lack of DHT means the male organs don't develop properly, according to the National Institutes of Health.

    When children with the condition are born, their external genitals look female, or in some cases, appear ambiguous, the NIH says. But during puberty, Guevedoces, like typical males, experience an increase in testosterone. The body appears to respond to these higher levels of testosterone — the penis and scrotum grow larger, and secondary sex characteristics — such as increased muscle mass and a deep voice — can also appear.

    Men with this condition, officially called 5-alpha reductase deficiency, are usually infertile, and often do not develop much facial or body hair. Although most children with this condition are raised as girls, about half identify themselves as male after puberty, the NIH says. [7 Diseases You Can Learn About From a Genetic Test]"

    https://www.livescience.com/52247-guevedoces-girls-boys.html
     
    #68 BadInvertor, Jul 30, 2019
    Last edited: Jul 30, 2019
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  9. Armando Jose

    Armando Jose Senior Member My Regimen

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    In the study from Imperato don´t talk about which type of 5 AR´s is affected. 1, 2 or 3, or all?
    IMHO Complete Androgen deficiency is not compatible with the human life.

    It is not a white/black issue
    "Currently, approximately 900 different mutations have been associated with AIS according to an AR gene mutations database [12,56]"
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480640/
    Interesting, no any word about the three types of AR.

    And, I am wondering if these pseudohemaphrodytes have sebum in hair scalp?
     
    #69 Armando Jose, Jul 31, 2019
    Last edited: Jul 31, 2019
  10. stachu

    stachu Experienced Member My Regimen

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    Scared of PFS? Eat Dutasteride!

    Buy now! at "www bla bla bla" Promotion ends tommorow!


    :D
     
  11. BadInvertor

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    From what i recall reading somewhere they have 1 and 3 or something like that, missing only the type 2 one.. And from what i recall both finasteride and dutasteride block type 1 also, not just 2 like it's said that finasteride does... dutasteride blocked all 3 of them i think and finasteride just 1 and 2 or something like that, correct me if i am wrong...
     
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  12. Armando Jose

    Armando Jose Senior Member My Regimen

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    Finas block mainly type 2 (if the use is chronic also block type 1), Dutas blocks 1 and 2 types,
     
  13. BadInvertor

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    I saw recently on this site some studies posted by a member that shows finasteride blocks 1 and 2 and dutasteride all 3 of them.. In what manner i can't recall but i will take a look and see if i can find the post !
     
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  14. Pigeon

    Pigeon Senior Member My Regimen

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  15. baba_yaga

    baba_yaga Established Member My Regimen

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    finasteride does have sides, and the studies may have claimed unrealistic numbers. But we shouldnt loose finasteride as a potential option for hair loss treatment. It is the only effective approved treatment for hair loss since ~20 years for fucks sake.
     
  16. Pigeon

    Pigeon Senior Member My Regimen

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    I can agree with the fact that if people are really depressed about their hairloss, fina should still be an option. BUT we need all the real results so people can make an objective decision. Some new long term (2-3+ years) studies are in order.
     
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  17. petersonKj

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    there is many other long term finasteride studies, you just don't like their results
     
  18. Pigeon

    Pigeon Senior Member My Regimen

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    Because they're done by special interest groups like hair transplant surgeons. And we don't know about the quality of those studies.
     
  19. INT

    INT Senior Member

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    Says who. LOL
     
  20. baba_yaga

    baba_yaga Established Member My Regimen

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    Agreed. New studies in the works?
     

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