Exploring The Hormonal Route. Hair=life.

[Get my hair back]

Okay. Can you track the level of PRL or density of PRLR in the skin, without biopsy?

 

[Get my hair back]

The standard pattern of alopecia is not just T and DHT.

 

[SavingMyHair]

The standard pattern of alopecia is not just T and DHT.

I know but my case is weird. I recovered all my hair once on dutas + minoxidil, but after a while dutas stopped work and my dht was high even on dutas.

 

[Get my hair back]

What are you doing now to suppress DHT?

 

[SavingMyHair]

What are you doing now to suppress DHT?

Estradiol injections, dutasteride and bicalutamide

 

[Get my hair back]

Estradiol injections, dutasteride and bicalutamide

And the tests systemic DHT decreased?

 

[Get my hair back]

We need to pressurize DHT not only in the periphyric tissues, but also systemically.

 

[SavingMyHair]

And the tests systemic DHT decreased?

I dont know now. When I had 1011 T induced by dutas and before HRT, my DHT was 59 ng/dl. After starting HRT with CPA + shitty e2 spray (180 ng/dl T and 20 pg/ml e2) my DHT decreased to 39 ng/dl(still high). Now with injections plus bicalutamide im pretty sure those level has to be even lower, because everything changed: less body odor, very slow growth and less body hair/beard growth, no oily skin, no sperm at all etc. With that and low 3 a diol g, I can guess my DHT is under 10 ng/dl now.

 

[SavingMyHair]

We need to pressurize DHT not only in the periphyric tissues, but also systemically.

Yeah but peripheral could be even more important. The user @GRme11 is one of the best examples. When he recovered his hair, he had high DHT levels but his 3a diol g was low, so he recovered his hair. Now his 3 a diol g spiked and he is losing his hair very very fast and aggressively.

 

[Get my hair back]

Absolutely. But Androgenetic Alopecia on systemic 10% DHT can progress, with high receptor sensitivity.
People with 5AP deficiency don't get baldness.

 

[dar3k]

Hi, maybe some of you guys remember me… So I decided to give a try to HRT to save/reverse my hairloss. Unfortunately NOTHING works on me.

I have been on 50mg bicalutamide ed + 4 mg estradiol + 10mg oral minoxidil ed + 0.5mg dutasteride ed + 1mg finasteride ed + 150mg RU58841 + 20mg Pyrilutamide (2 x 10mg) + Topical minoxidil 2 x day + Rosemary Oil ed

My blood test after 1 month on HRT:
T: 1.5nmol/l
E2: 239 pg/ml
DHT: 39pg/ml

After 3 months:
T: 0.9nmol/l
E2: 289pg/ml
DHT: 26pg/ml

After 6 months:
T: 0.6nmol/l
E2: 233pg/ml
DHT: undetectable

I also did a blood test for thyroid tsh, ft3, ft4, ferritin, iron, b12, prolactin and everything was fine.


It slowed down a bit my hair loss but after 8 months my hairs are thinner. My crown is much thinner, still receeding, temple peaks literally disapeared, my hairs are still miniaturizing.

All I want to say to you guys, HRT - even with proper female levels, even with undetectable DHT values is not guarantee to hairloss. As you can see for example on Reddit /femalehairloss a lot of women with normal female hormone levels are going bald too. They have diffuse thinning/female pattern baldness/receeding hairlines etc.

If you want to try HRT/pyrilutamide/RU etc. of course you can do it, but remember that there is no GUARANTEE to stop/reverse hairloss.

 

[Get my hair back]

It is possible that the PRL/PRLR in the skin is off the charts and any method, even HRT, will be powerless.
And maybe it is something autoimmune, have you tried topical immunosuppressants?

 

[SavingMyHair]

It is possible that the PRL/PRLR in the skin is off the charts and any method, even HRT, will be powerless.
And maybe it is something autoimmune, have you tried topical immunosuppressants?

I also use cloboetasol propinoate topically and is not working, not even for the scalp tenderness

 

[Get my hair back]

Maybe Clobetasol Propionate? If so, this glucocorticoid has no immunosuppressive properties.

 

[SavingMyHair]

Maybe Clobetasol Propionate? If so, this glucocorticoid has no immunosuppressive properties.

I even used oral betamethasone last summer and scalp tenderness never stopped.

 

[Fvgwnx]

T level?

I understand that 1 bottle of EE is enough for a year? o_0 how much did the shipping cost?

 

[SavingMyHair]

I understand that 1 bottle of EE is enough for a year? o_0 how much did the shipping cost?

OElabs shipment is 7€, at least for Europe, but you need to buy 2 vial minimum.

 

[Fvgwnx]

OElabs shipment is 7€, at least for Europe, but you need to buy 2 vial minimum.

I want to order from noirelabs.net. you can buy one there.

 

[Fvgwnx]

ЛИ

OElabs shipment is 7€, at least for Europe, but you need to buy 2 vial minimum.

they pay in bitcoins, but is there where you can pay by bank transfer?

 

[SavingMyHair]

ЛИ

they pay in bitcoins, but is there where you can pay by bank transfer?

AFAIK, no.