Exploring The Hormonal Route. Hair=life.

JaneyElizabeth

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Petition For Hair Rights for All Human Beings

I am going to set up a petition thread whereby we all sign demanding that hair services be covered for everyone, male, female and all transgender individuals. I will work on the legal wording and let' see how many folks we can get to sign and since I am in DC and all, I would look into getting media to the benefits of our worldwide hair-concerned cohort.

Acne's covered; dermatitis too; f*****g tretinoin is covered by insurance.

We demand that hair systems, transplants, medications for XY's, XX's, Inter-sex folks, male, female other regardless of sexual preference or designation, or any other needed services including psycho-therapy be made available at charge of the State in all countries who are signatories to the United Nations.

We can do individual ones for different countries. I do speak Spanish, French, Portugues and Italian, well, I struggle a bit in Italian since it is half French and Half Latin to my ears plus I know enough German to get it done there too. None of us are of low intelligence and we are on here all of the time. Let's do something productive that feeds my ego....<winks> Oops. Strike that part.

Sincerely,

Janey Elizabeth Loeffler, Esq.
Washington DC
Member Maryland and DC Bars


No more whining or moping or incel jokes. Let's start a movement for everybody. Hair is a human right. I feel very strongly about this although I seldom have strong opinions otherwise. We are cooped up. Let's strike a blow for history.
 

JaneyElizabeth

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If we get a mass of signatures then we can request the owner communicate with other hair sites. If folks give me names of hair sites in any of my languages, I will post the petition in those places too.
 

Ephemeral-Kitten

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You will love my post somewhere about the right to puberty blockers because females have biological realities related to transitioning successfully and we aren't going to see any more girls stranded without hair in their teens....

And XY males deserve to have their hair loss viewed as equally dysphoric and have their hair care covered by insurance...
Well, most transsexual women are also XY (some are XX with autosomally activated SRY gene, but that's much more rare).

I don't think the degree of dysphoria from it is quite the same in most cases, however I do agree it is disfiguring and should be covered by insurance.
 

JaneyElizabeth

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Well, most transsexual women are also XY (some are XX with autosomally activated SRY gene, but that's much more rare).

I don't think the degree of dysphoria from it is quite the same in most cases, however I do agree it is disfiguring and should be covered by insurance.
Just posted my Hair is a Human Right of All Petition Thread. I will of course want your input so I don't offend anybody and then we need to find someone else EK to make sure that you don't offend anybody:)
 

JaneyElizabeth

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Well, most transsexual women are also XY (some are XX with autosomally activated SRY gene, but that's much more rare).

I don't think the degree of dysphoria from it is quite the same in most cases, however I do agree it is disfiguring and should be covered by insurance.
Doesn't matter. We aren't fighting over deductibles. This is a socialist human right for all folks without getting into who is more oppressed. You and I both know that there's about 99 percent of things that can suck about being male just like being trans.
 

Ephemeral-Kitten

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Doesn't matter. We aren't fighting over deductibles. This is a socialist human right for all folks without getting into who is more oppressed. You and I both know that there's about 99 percent of things that can suck about being male just like being trans.
Well, my dysphoria regarding bones is similar to with hair, but many cis men tell me only the hair thing bothers them or sometimes not even that. My thoughts on the feelings of cisgender males is purely speculative. But I do support healthcare coverage for hair loss.
 

Ephemeral-Kitten

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Baldness is not associated with any conditions that present immediate danger to life.

Comparing it to cancer is when they start to wonder about our ability to rationally categorize conditions in life. It mostly impacts white and Semites and mixtures of the two not everyone like cancer does. It is not a disease and scarce resources might be taken away from Covid and cancer research and other more immediate dangers. Because wigs always have existed and it can be treated among those who take quick action.

This is another version of a post that someone else just put up.
>covid

It's related to hair loss anyway.

>In the report, the deaths per hundred thousand residences for counties consisting of a majority white, Asian, black, and Hispanic populations was 1.1, 0.4, 6.3, and 0.6, respectively.

>There is undoubtedly a multifactorial etiology to this racial disparity that can include socioeconomic as well as other factors. However, a similar racial bifurcation is evident in conditions influenced by sensitivity to androgens, for example, prostate cancer and androgenetic alopecia.

>Polymorphisms in the length of CAG repeat in exon 1 of the androgen receptor have been shown to correlate with incidence of prostate cancer.

>Binding of SARS‐CoV‐2 to ACE2 is mediated by proteolytic cleavage of a viral surface protein by transmembrane protease, serine 2 (TMPRSS2).7-9 As such, concentrations and activity of both ACE2 and TMPRSS2 in host pneumocytes are crucial to SARS‐CoV‐2 ability to infect a host. Both ACE2 and TMPRSS2 are regulated by the androgen receptor; in fact, the 15‐base‐pair androgen response element is the only known transcription promoter for the TMPRSS2 gene.10-13 Androgen‐mediated expression of ACE2 and TMPRSS2 may explain the gender difference in COVID‐19 disease severity and mortality.

>If androgen sensitivity can be confirmed as a predisposition to SARS‐CoV‐2 disease severity, it could suggest the use of anti‐androgens or androgen‐modulating drugs as a means of treatment, either alone or combined with TMPRSS2 inhibitors. For example, anti‐androgens like bicalutamide and enzalutamide or androgen modulators like finasteride and dutasteride may be beneficial.
 

JaneyElizabeth

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>covid

It's related to hair loss anyway.

>In the report, the deaths per hundred thousand residences for counties consisting of a majority white, Asian, black, and Hispanic populations was 1.1, 0.4, 6.3, and 0.6, respectively.

>There is undoubtedly a multifactorial etiology to this racial disparity that can include socioeconomic as well as other factors. However, a similar racial bifurcation is evident in conditions influenced by sensitivity to androgens, for example, prostate cancer and androgenetic alopecia.

>Polymorphisms in the length of CAG repeat in exon 1 of the androgen receptor have been shown to correlate with incidence of prostate cancer.

>Binding of SARS‐CoV‐2 to ACE2 is mediated by proteolytic cleavage of a viral surface protein by transmembrane protease, serine 2 (TMPRSS2).7-9 As such, concentrations and activity of both ACE2 and TMPRSS2 in host pneumocytes are crucial to SARS‐CoV‐2 ability to infect a host. Both ACE2 and TMPRSS2 are regulated by the androgen receptor; in fact, the 15‐base‐pair androgen response element is the only known transcription promoter for the TMPRSS2 gene.10-13 Androgen‐mediated expression of ACE2 and TMPRSS2 may explain the gender difference in COVID‐19 disease severity and mortality.

>If androgen sensitivity can be confirmed as a predisposition to SARS‐CoV‐2 disease severity, it could suggest the use of anti‐androgens or androgen‐modulating drugs as a means of treatment, either alone or combined with TMPRSS2 inhibitors. For example, anti‐androgens like bicalutamide and enzalutamide or androgen modulators like finasteride and dutasteride may be beneficial.
I am with you but we need to set up document storage so I can go through things one by one plus there must be some other lawyers who are bald and willing to admit it.... Anybody?
 

JaneyElizabeth

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Well, my dysphoria regarding bones is similar to with hair, but many cis men tell me only the hair thing bothers them or sometimes not even that. My thoughts on the feelings of cisgender males is purely speculative. But I do support healthcare coverage for hair loss.
Yeah sis but we aren't on a bone site... :)
 

Ephemeral-Kitten

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He is a mysterious case. Lol. You can tell by his hairline that his aromatization genes are IMPRESSIVE, despite of the aggressive male pattern baldness (early onset).
Ikarus is also a unique case. He had E2 in excess of 250 pg/ml on 2 mg buccally, normally it would take a higher dose like 6 mg to have such an effect on plasma levels at nadir.
 

JaneyElizabeth

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Ikarus is also a unique case. He had E2 in excess of 250 pg/ml on 2 mg buccally, normally it would take a higher dose like 6 mg to have such an effect on plasma levels at nadir.
Sigh. Dude, nobody has the ability to diagnose like that. Let's get you working on something productive. You seem to be a misplaced genius who needs a higher calling while you wait for your meds.... I could use your help and we have Tato to put together mumbo jumbo that impresses the real scientists... Let's get you covered. If Germany isn't covering hair then back to the DDR. Why are the people struggling most on here living in Europe?
 

Ephemeral-Kitten

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Yeah, and because of that I see no reason taking high E, maybe E not at all, because Bica gives you already the E you need...

Am I right!?
No, because without something to replace the blocked androgens at the HPG axis (like estradiol) it will sense the decrease in sex hormones and cause your LH to rise as a consequence which will then cascade into more testosterone and DHT, which can then eventually over power the blockade. There has to be something to bind to the hormone receptors to tell the HPG axis you don't need more sex hormones; it's a bit like an adventure show like Indiana Jones or something, where there's a trap and you need to replace the treasure you're taking with something of a similar size/weight.

Additionally, T, DHT and E2 all down regulate the AR, but androgens that are blocked can't do it, so you'd rely on estrogens to prevent your androgen receptor sensitivity from spiraling out of control.
 
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Ephemeral-Kitten

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But understand that in certain cases your body takes the "necessary" steps to return to homeostasis and you are as I have said an XY your homeostasis is not blocking AR

Your body does this with glucose and its insulin receptor and you develop diabetes, the idea is similar, I want you to note that you don't need a cancer for your body to make adaptations.
It doesn't really have to do with chromosomes. At least not the Y chromosome; the androgen receptor is X-linked.

However, without a primary sex hormone to bind to the ARs, they will become hypersensitive in an effort to maintain homeostasis, you're right about that, it's just not linked to birth sex. In the case of females there is usually some other endogenous sex hormones that will prevent the receptor density from going too far, notably estradiol.
 

Pls_NW-1

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I am quite afraid, I read studies and anecdotal reports that Bica does not upregulate androgen receptors, nevertheless, they will get anyways flooded by Bica molecules. After stopping, yes, you will experience steroid-like symptomes.

I also want to say that I don't want to swap my T : E ratio from T to E, want to stay a man, am not transgender. Because of that I refuse to take E, hope you understand what I mean.

If I would take E + bica, I will surely change a lot, I dont want that, it's like gender dysphoria, you guys experience, before transitioning.

All in all, I think Bica will be enough, it's only silencing androgen signaling through corepressors and not androgen activation for bones, muscles, etc.
And the aromatized E will as well be enough, for sure, cause chemically, the dominant hormone is anyways, T, still.

We just need the appropriate dosage, adjusted to our T levels.
 

Pls_NW-1

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I still try to figure out how to get rid of dandruff!? Or inflammation... :( can't get anywhere viable informations.
 

Yar

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Прогестерон не принес мне никакой пользы, и я принимал его в рецептурных дозах.

Ничто так не способствует росту волос, как эстроген, да, другие гормоны должны быть в равновесии, но если серьезно, если это проблема, продолжайте наносить эстроген местно и принимайте экзогенный прегненолон.

Прогестерон напрямую конкурирует с эстрогеном и останавливает рост волос, который вы получаете от E2, ТОЧНО так же, как когда женщины испытывают преобладание прогестерона, их кожа превращается в дерьмо, и они действуют психотически.
It's not like that,it's just the opposite
 

tato123

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If it weren't for high gynecomastia I would go on bicalutamide today.

I have a predisposition for gyno, the women in my family have full breasts and my father has a lot of breasts because he is obese, but he has gynecomastia, his chest halos are giant.

So it is certain that bicalutamide will give me a very beautiful pair of breasts.

My fear is not being a controllable gyno.

Bicalutamide is a 90% chance of gyno.

If I was sure it would be a mild or moderate gynocomastia I would take it without any problems, my fear is losing control since bicalutamide is for the rest of my life, the most positive point of bicalutamide is the preservation of the HPT axis in my opinion.


All effective protocols tend to kill our fertility, but bicalutamide is "safe" in that sense.

My fear is to develop massive breasts fast .

I do not care for mild and moderate feminization I am a short 175cm man, I look good with feminine features and so I have done, but I do not seek full breasts , despite accepting some level of gyno

I read some studies that 100% of transsexuals treated with Bicalutamide developed full breasts.

The half-life of bicalutamide is 5-7 days if I'm not mistaken.

I think if it would be feasible to give intervals of 2 days or 1 day between doses of 50mg

It would decrease the risk of gyno but it would also decrease serum levels of bicalutamide, that is, it would not actually increase that much.

I see people making dutasteride once a week together with finasteride every day, I wonder if it is possible to do something with bicalutamide in this regard, but not like that, it is something to mature in the mind





How are things out there @Almas
 

Pls_NW-1

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If it weren't for high gynecomastia I would go on bicalutamide today.

I have a predisposition for gyno, the women in my family have full breasts and my father has a lot of breasts because he is obese, but he has gynecomastia, his chest halos are giant.

So it is certain that bicalutamide will give me a very beautiful pair of breasts.

My fear is not being a controllable gyno.

Bicalutamide is a 90% chance of gyno.

If I was sure it would be a mild or moderate gynocomastia I would take it without any problems, my fear is losing control since bicalutamide is for the rest of my life, the most positive point of bicalutamide is the preservation of the HPT axis in my opinion.


All effective protocols tend to kill our fertility, but bicalutamide is "safe" in that sense.

My fear is to develop massive breasts fast .

I do not care for mild and moderate feminization I am a short 175cm man, I look good with feminine features and so I have done, but I do not seek full breasts , despite accepting some level of gyno

I read some studies that 100% of transsexuals treated with Bicalutamide developed full breasts.

The half-life of bicalutamide is 5-7 days if I'm not mistaken.

I think if it would be feasible to give intervals of 2 days or 1 day between doses of 50mg

It would decrease the risk of gyno but it would also decrease serum levels of bicalutamide, that is, it would not actually increase that much.

I see people making dutasteride once a week together with finasteride every day, I wonder if it is possible to do something with bicalutamide in this regard, but not like that, it is something to mature in the mind





How are things out there @Almas
You need to take bica every day, so it can build up in your system. The AR's need to be flooded. You will have to contain at the end of the week: 350+mg Bica in your body.

As for gyno: I think starting raloxifene within Bica together would be good. But I am not sure if it is bad for the hair...

What about gyno surgery!? Can it be permanent!? What will the chest look like? :(
 

tato123

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You need to take bica every day, so it can build up in your system. The AR's need to be flooded. You will have to contain at the end of the week: 350+mg Bica in your body.

As for gyno: I think starting raloxifene within Bica together would be good. But I am not sure if it is bad for the hair...

What about gyno surgery!? Can it be permanent!? What will the chest look like? :(
Thanks for the information , I didn't know that 350mg was needed for the drug to be effective.

If I am not mistaken, Raloxifene competes with the estrogen receptor, this will end your hair, I think it is not a good one, every medicine for gyno control and fertility is terrible for the hair.

The problem with gyno is when I can do the surgery, I need time I am in a phase of life now that I cannot stop 30 days to operate the breasts, it is a serious thing although simple, I could expect surgery without problems with small breasts , now waiting for surgery with full breasts is a problem.

Damn this is torture.

The apparent elixir comes with giant AR sensitivity and strong breasts too, the only problems with this drug.

I will wait for our friends and see their results.

Does anyone know how EIN's breasts looked?
 
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