Do Non-responders Just Have Really High Dht ?

michel sapin

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sure. i am still on propecia even if i don't respond .
the range here in france is 0,40 to 1,38 pg/ml .
when i first started 2 years ago my baseline was 0,56 . then after 6 month i was at 0,27 , then after 1 year i was at 0,14 . then i tried 5 mg propecia for 6 month and i was at 0,13 .
So you can see there is no difference between 1 mg and 5 mg .
SO basically i got all the sides effect from propecia because of the really low dht , but not the positive effect . great !
 

stump

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It makes sense logically that those with higher dht would be better responders. This is because dht levels don't dictate whether a person is bald or not. I believe that there is a dht threshold and if above this, a person starts to bald. So if a person is balding, they would need to lower their dht below this level. This means that this threshold can be anywhere below this person's current level. There are simply more numbers below a high number than there is a low number.

Also, since dht is lowered by a percentage by finasteride, a higher base level would be more of a drastic change in dht level.

It would be interesting to find out if side effects are more common if one goes below the minimum level of dht needed for sexual function or if even drastic changes cause side effects as well. By this I mean going from like 85ng/mL to like 30ng/mL. 30 is still above the minimum commonly cited level of acceptable dht but this is still a huge change in what this hypothetical person's dht once was. Would this huge drop cause side effects? Or are side effects more common in those with moderate dht levels since they would experience a huge drop and potentially below the minimum level? Or do those with low base dht experience more side effects because they were low to begin with?
 

DoctorHouse

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Doctor, unless you have been on finasteride 1mg daily for long term without any breaks and have dropped below baseline then I'm afraid these claims are unsubstantiated. My highly respected doctor in the NYC area who prescribed it to me said this is not the case for his hundreds of patients. Also, the finasteride 5 year and 10 year medical studies also don't show that you will lose ground (at least the vast majority.) Only 10% and 7% dropped below baseline respectively, and it's not like this minority of men went bald. They might have dropped a norwood level or two.

I am quite confused as to why some people on this forum believe this is the case. Maybe a patient's hair will get a bit thinner due to age related thinning while on the drug, but this won't happen until you're an old man if it happens at all. It's not like you're going to go completely bald in areas that you would had you never taken the drug.

Anyway, why should I take the time to argue with some of you guys on this forum? I have a full head of teenage thick hair because of the drug. Best of luck guys.
Been on Propecia for 11 years( don't know if that is long term to you) with no breaks. Still below baseline and my barber just confirmed tonight I am getting worse. But I must be the 10 per cent that dropped a Norwood level on it. But it has helped me maintain a good amount of hair. I hope Follica has some encouraging news for all us.
 

sunchyme1

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Been on Propecia for 11 years( don't know if that is long term to you) with no breaks. Still below baseline and my barber just confirmed tonight I am getting worse. But I must be the 10 per cent that dropped a Norwood level on it. But it has helped me maintain a good amount of hair. I hope Follica has some encouraging news for all us.

11 f*****g years? jesus christ

does your dick still work?
 

DoctorHouse

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DoctorHouse

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i cringe at you long term guys taking this stuff. i cant be arsed to go around bashing finasteride, but it cannot be healthy taking this stuff for so long
What about all the men that take Proscar at 5mg and Avodart for the rest of their life? They seem fine.
 

hairblues

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i cringe at you long term guys taking this stuff. i cant be arsed to go around bashing finasteride, but it cannot be healthy taking this stuff for so long

for what scientific reason?

I would think its just not good if not fully matured. Not after men start to age (25?)
 

jetlife1

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At least you can admit that it is a small percentage @DoctorHouse

What Norwood were you upon starting and what are you now? Also, any chance you can share pics? Like several users claiming about it losing its effect on this forum, maybe you're not as bad as you think.
 

kj6723

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i cringe at you long term guys taking this stuff. i cant be arsed to go around bashing finasteride, but it cannot be healthy taking this stuff for so long

for what scientific reason?

I would think its just not good if not fully matured. Not after men start to age (25?)

This is bro-sciency on my part, but if your hormones are at a level where you're experiencing no adverse reactions, and you keep them there(by taking the same dosage indefinitely), is this really that big a risk? Seems to me you're body would basically be in a state of homeostasis
 

DoctorHouse

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At least you can admit that it is a small percentage @DoctorHouse

What Norwood were you upon starting and what are you now? Also, any chance you can share pics? Like several users claiming about it losing its effect on this forum, maybe you're not as bad as you think.
Not going to share any photos. However, I started at around a NW1.5 with relatively thicker hair and now close to a NW2A with diffuse thinning all over including the donor/crown. Temple points thinning too.
 

sunchyme1

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for what scientific reason?

I would think its just not good if not fully matured. Not after men start to age (25?)

your lowering a hormone that makes you a man. you see that thread today about a guy stopping finasteride after 10 years of use? his test levels are that of 50 year old man. and has all the other effects of low dht low test etc. ive read countless of threads like this over the years.

its the older guys who cant really feel it because their hormones are already in decline. its only ofter stopping the drug so they realize whats going on. the weight gain, depression, tiredness etc. all of that sh*t gets better. they think its just age but its not

look i cant be arsed to go around bashing finasteride, if you feel fine then good for u, but after what i went through for only a year im super f*****g wary now about my health.

id rather go the opposite way as i get older and try to boost all my manly hormones. so i keep in shape better, feel better, look better. all of the good stuff. i dont wana suppress anything
 

sunchyme1

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This is bro-sciency on my part, but if your hormones are at a level where you're experiencing no adverse reactions, and you keep them there(by taking the same dosage indefinitely), is this really that big a risk? Seems to me you're body would basically be in a state of homeostasis

some guys cant tell there getting sides. thats the problem. guys like worm. he used finasteride for years. went away for a couple weeks forgot his finasteride, and felt great. more energy, more motivation etc etc. never went back on it again

i dont wana discourage u. if u feel fine then good for u
 

jetlife1

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Not going to share any photos. However, I started at around a NW1.5 with relatively thicker hair and now close to a NW2A with diffuse thinning all over including the donor/crown. Temple points thinning too.

I mean that's not horrible. Maybe it isn't as bad as you think? Personally, I'm a thick Norwood 1.5 right now.

Hopefully better stuff comes in the future, especially for people like yourself who lose ground on Propecia.
 

Afro_Vacancy

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some guys cant tell there getting sides. thats the problem. guys like worm. he used finasteride for years. went away for a couple weeks forgot his finasteride, and felt great. more energy, more motivation etc etc. never went back on it again

i dont wana discourage u. if u feel fine then good for u

Most likely it.
 

DoctorHouse

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I mean that's not horrible. Maybe it isn't as bad as you think? Personally, I'm a thick Norwood 1.5 right now.

Hopefully better stuff comes in the future, especially for people like yourself who lose ground on Propecia.
I am not saying its horrible. My point was it's no cure and it does not stop hair loss in its track like some people believe. And some people can go below baseline on it. Another poster on here went to Dr Bauman and he claims finasteride can lose its effectiveness and he recommends them switch to dutasteride.
 

sunchyme1

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I am not saying its horrible. My point was it's no cure and it does not stop hair loss in its track like some people believe. And some people can go below baseline on it. Another poster on here went to Dr Bauman and he claims finasteride can lose its effectiveness and he recommends them switch to dutasteride.

Doctor how old r u? hows your weight and energy levels compared to 11 years ago? sex drive? mood?
 
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