Complete Crown Regrowth - Topical Dutasteride

hailbrotzu

Established Member
My Regimen
I made a DHT Blood Test yesterday. If my levels are in the norm I will maybe test the topical Duta 0.1% from Pharmacia Parati since I am scared from this sh*t due to my topical finasteride experience

For the record: I checked my DHT on 1% Topical Finasteride from Pharmacia Parati and my DHT was as low as on 1mg oral Finasteride!

Did anyone test 5-10% Urea or Ceramide creme for improving your skin barrier so that less topical will be absorbed into the blood stream?

I would be willing to try Urea for this. I am also wondering if microneedling overtime could damage the skin barrier. Would you have to continually use urea?
 

Mustang

Established Member
My Regimen
Topical finasteride will penetrate
Topical dutasteride won't. At least not even close
I used 50MG, Yes. FIFTY!, 100 times the oral dose and still had more DHT than with oral finasteride.
 

ButWhyTho

Established Member
My Regimen
Could you share more pictures of your progression? I think you stated you've been experiencing hair loss for the last decade or so. I would really appreciate a linear progression of your hair gain specially since the surgical interventions likely had a drastic effect. Also do you believe someone else could achieve similar results without FUE and only topical duta?
 

pegasus2

Senior Member
My Regimen
Could you share more pictures of your progression? I think you stated you've been experiencing hair loss for the last decade or so. I would really appreciate a linear progression of your hair gain specially since the surgical interventions likely had a drastic effect. Also do you believe someone else could achieve similar results without FUE and only topical duta?

No. His regrowth has been entirely due to FUE. Since his last operation his crown is exactly the same, except it's parted differently in his after picture. If you look closely you can see the thin spot is still there in the same place. This is the worst success thread on here.
 

Pigeon

Senior Member
My Regimen
No. His regrowth has been entirely due to FUE. Since his last operation his crown is exactly the same, except it's parted differently in his after picture. If you look closely you can see the thin spot is still there in the same place. This is the worst success thread on here.
Lol, let Mustang answer that.
 

pegasus2

Senior Member
My Regimen
Lol, let Mustang answer that.
Mustang is deranged and retarded. I'm sure he'll respond with some nonsense that I won't even bother reading. Somebody had to call out this delusional thread. The guy thinks his special formulation works because it's "Liposomal", but he doesn't even know what that means. Buzzwords like that are mostly used to scam people out of their money.
 

Pigeon

Senior Member
My Regimen
Mustang is deranged and retarded. I'm sure he'll respond with some nonsense that I won't even bother reading. Somebody had to call out this delusional thread. The guy thinks his special formulation works because it's "Liposomal", but he doesn't even know what that means. Buzzwords like that are mostly used to scam people out of their money.
Lol, what did he do to you? So far his claims seem legit, why would he lie anyway? And Lupunzula claims the same about topical duta:

https://fuehairdoctor.co.uk/topical-dutasteride-dr-lupanzula
 

blub10

Established Member
My Regimen
Pegasus stop spreading wrong info and attacking Mustang. Mustang did great with his contribution to this forum by sharing for the first time a FUE scar repair!

Lupanzula is not selling nor producing topical dutasteride, its Pharmacia Parati. Moreover I did a consulting with him in Nov. 2018 and back then he recommended topical finasteride, also from Parati. His post on Dutasteride is way older

I guess Ceramides and Urea has to be used continuously since anything that contains alcohol will damage the skin barrier, also micro needling!

My minoxidil side effects also started after 8 weeks of use which I attribute to an damaged skin barrier due to the containing alcohol with damage the skin. This also the reason why people claim minoxidil makes their skin look older, it's the alcohol not the minoxidil!!
 

SausageDawg

Established Member
My Regimen
Mustang is deranged and retarded. I'm sure he'll respond with some nonsense that I won't even bother reading. Somebody had to call out this delusional thread. The guy thinks his special formulation works because it's "Liposomal", but he doesn't even know what that means. Buzzwords like that are mostly used to scam people out of their money.

Okay so you may think his regrowth is from the FUE but what about him anecdotally stating that he has no more hair loss? Maybe regrowth is far fetched but it could maintain! Or are you of the opinion topical dutasteride does not work AT ALL? :)
 

pegasus2

Senior Member
My Regimen
Okay so you may think his regrowth is from the FUE but what about him anecdotally stating that he has no more hair loss? Maybe regrowth is far fetched but it could maintain! Or are you of the opinion topical dutasteride does not work AT ALL? :)

After all of his hair transplants does he even have any native hair left on the top of his head? Likely is only the strongest strands that you would see him hanging onto into old age regardless. I'm of the opinion that we don't know if it works, asks this case just isn't very solid evidenc. I use topical dutasteride, but I'm not banking on it, I use oral too.



It would be naive to think Lupunzula doesn't get a kickback on the topical dutasteride he prescribes.

Minoxidil causes skin problems because of the up regulation of pgf2a.
 

dgadgdea

Member
My Regimen
Now we're getting somewhere gents -- enjoying the exchange.

For my part I'm desperate enough to try. If there's a chance at crown regrowth without finasteride sides I'll give it a shot.

First question: do any of you that are more knowledgeable about skin layers, molecular weight, daltons, etc. have an opinion about the underlying theory that a topical dutasteride will somehow not be absorbed systemically the way topical finasteride is?

I received this topical dutasteride, lipsomal at 0.5%. I’m planning to wait a total of 4 weeks after taking my last finasteride dose to confirm that side effects subside (has worked in the past) then get detailed lab work to get a sense of baseline T, DHT, and everything else.

Second question: Having looked at a lot of dutasteride experiences on here, a significant number of people seem to think that dutasteride is effective on the crown but ineffective or possibly even damaging on the hairline. The thought occurred to me to begin by just applying to the crown and not the hairline. What do we know about the whole “dutasteride shreds the hairline” thing? Wives tale? Valid concern?

I was also planning to continue microneedling weekly or biweekly at ~1-1.5mm, but would make sure to wait ~3 days after topical dutasteride application. Bad idea? I’m hoping this will not increase systemic absorption but I’m in broscience territory here.

Appreciate any thoughts/theories.
 

Pigeon

Senior Member
My Regimen
Now we're getting somewhere gents -- enjoying the exchange.

For my part I'm desperate enough to try. If there's a chance at crown regrowth without finasteride sides I'll give it a shot.

First question: do any of you that are more knowledgeable about skin layers, molecular weight, daltons, etc. have an opinion about the underlying theory that a topical dutasteride will somehow not be absorbed systemically the way topical finasteride is?

I received this topical dutasteride, lipsomal at 0.5%. I’m planning to wait a total of 4 weeks after taking my last finasteride dose to confirm that side effects subside (has worked in the past) then get detailed lab work to get a sense of baseline T, DHT, and everything else.

Second question: Having looked at a lot of dutasteride experiences on here, a significant number of people seem to think that dutasteride is effective on the crown but ineffective or possibly even damaging on the hairline. The thought occurred to me to begin by just applying to the crown and not the hairline. What do we know about the whole “dutasteride shreds the hairline” thing? Wives tale? Valid concern?

I was also planning to continue microneedling weekly or biweekly at ~1-1.5mm, but would make sure to wait ~3 days after topical dutasteride application. Bad idea? I’m hoping this will not increase systemic absorption but I’m in broscience territory here.

Appreciate any thoughts/theories.
Be sure to quit needling if you go on topical duta.
 

blub10

Established Member
My Regimen
I did some research here on the forum. One member claimed to have stronger side effects in topical Duta than on low dose oral finsteride. So far only Mustang claims having less side effects which is not too much of an evidence, especially without good photos, nevertheless I really like his Scar Repair thread

@Pegasus, there are studies on alcohol causing skin aging. Is your claim of PGA backed up by any scientific paper?

Furthermore Mustang does not tell which Doctor or pharmacy did produce it and doesn't want to disclose the formula. From I heard it's from Dr. Mw*mba, not Lupanzula. 30ml finasteride ordered directly at Parati costs about 30 Euro + shipping ; Duta 50Euro + Shipping. I do not believe that both of these surgeons do get any mentionable commission that interests a surgeon (maybe 10 Euro per monthly order if at all)

But needless to say, I also had a consultation with Dr. Mw*mba. He is nice guy and took his time but but he tried to cross sell things which other reputable surgeons in Europe and Asia told me it is a waste of money such as "Whey Help Hair Protein", Prp with Acell and Hylauronic Acid, Shampoos of a certain brand, Laser Caps (I can even back this up with a proposal). So you never know

Nevertheless 50% DHT suppression from Mustang is quite a lot, but he uses a very high dose topical duta and claims the best regrowth ever. From my topical Fina Experience and study of oral Fina it makes almost no difference if someone takes 0.25mg oral finasteride compared to 1mg finasteride or 1% topical finasteride to 0.05% topical finasteride. I have a high suspicion that the same will occur to topical Duta
 
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blub10

Established Member
My Regimen
@dgadgdea

Before starting get 5 - 10% Urea cream with Ceramides. This will improve your skin barrier which could lead to less systemic absorption

And stop needling in the beginning

If you have no sides for several weeks stop the urea and ceramide creams, if still no sides start needling

All in all count your hairloss in the sink if you wash it
 

Stating facts

Member
My Regimen
Now we're getting somewhere gents -- enjoying the exchange.

For my part I'm desperate enough to try. If there's a chance at crown regrowth without finasteride sides I'll give it a shot.

First question: do any of you that are more knowledgeable about skin layers, molecular weight, daltons, etc. have an opinion about the underlying theory that a topical dutasteride will somehow not be absorbed systemically the way topical finasteride is?

I received this topical dutasteride, lipsomal at 0.5%. I’m planning to wait a total of 4 weeks after taking my last finasteride dose to confirm that side effects subside (has worked in the past) then get detailed lab work to get a sense of baseline T, DHT, and everything else.

Second question: Having looked at a lot of dutasteride experiences on here, a significant number of people seem to think that dutasteride is effective on the crown but ineffective or possibly even damaging on the hairline. The thought occurred to me to begin by just applying to the crown and not the hairline. What do we know about the whole “dutasteride shreds the hairline” thing? Wives tale? Valid concern?

I was also planning to continue microneedling weekly or biweekly at ~1-1.5mm, but would make sure to wait ~3 days after topical dutasteride application. Bad idea? I’m hoping this will not increase systemic absorption but I’m in broscience territory here.

Appreciate any thoughts/theories.

How about applying topical finasteride all other days of week or maybe less, and applying topical duta once? (which is also normal oral course for few people who can bear sides) People have claimed success on hairline with topical fina. For ex. see this guy using topical finasteride and min with needling for 10 months
 

Orwell

Member
My Regimen
I did some research here on the forum. One member claimed to have stronger side effects in topical Duta than on low dose oral finsteride. So far only Mustang claims having less side effects which is not too much of an evidence, especially without good photos, nevertheless I really like his Scar Repair thread

@Pegasus, there are studies on alcohol causing skin aging. Is your claim of PGA backed up by any scientific paper?

Furthermore Mustang does not tell which Doctor or pharmacy did produce it and doesn't want to disclose the formula. From I heard it's from Dr. Mw*mba, not Lupanzula. 30ml finasteride ordered directly at Parati costs about 30 Euro + shipping ; Duta 50Euro + Shipping. I do not believe that both of these surgeons do get any mentionable commission that interests a surgeon (maybe 10 Euro per monthly order if at all)

But needless to say, I also had a consultation with Dr. Mw*mba. He is nice guy and took his time but but he tried to cross sell things which other reputable surgeons in Europe and Asia told me it is a waste of money such as "Whey Help Hair Protein", Prp with Acell and Hylauronic Acid, Shampoos of a certain brand, Laser Caps (I can even back this up with a proposal). So you never know

Nevertheless 50% DHT suppression from Mustang is quite a lot, but he uses a very high dose topical duta and claims the best regrowth ever. From my topical Fina Experience and study of oral Fina it makes almost no difference if someone takes 0.25mg oral finasteride compared to 1mg finasteride or 1% topical finasteride to 0.05% topical finasteride. I have a high suspicion that the same will occur to topical Duta
I had the same experience with Dr Mwamba and his upselling of products, but he did agree to prescribe topical duta. I also thought he was pretty nice.

Overall, Mwamba said that he was not sure about the best dosing schedule, and that while dosing every 10 days or so has worked for one patient (I.e., Mustang) it wouldn't necessarily work for everyone. Dr Mwamba advised me to start off by applying every 4 or 5 days and see how I get on.

Unfortunately, he said he thought I was more likely than not to have side effects as I experienced them with topical finasteride, but that I could try topical duta and stop if necessary. This now leaves me with a decision to make.
 

Lurker85

Established Member
My Regimen
Be sure to quit needling if you go on topical duta.

What would be the difference between taking oral dutasteride and needling and applying topical dutasteride?

I'm using RU58841 and apply minoxidil + lclt 4 hours after RU application with light needling. I've been considering making a minoxidil + RU mixture to cut down on application time, but very on the fence about needling before using RU.
 
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