Recent content by violetfluff

  1. violetfluff

    Side Effects After 3 Propecia Pills?

    This is bad!...really bad!! The next stage is when the balls shrivel and turn black. Things will only go downhill from here. Have you had kids yet?
  2. violetfluff

    Propecia - 6 Months Shedding - Stop Or Continue?

    I'm afraid 6 months is not enough for many . Shedding can be high but what is the regrowth rate?. I didn't get a visible benefit until after 12 months. Some people are even longer.
  3. violetfluff

    Dutasteride And Finasteride, And Their Structures

    Yeah absolutely! On one diet I was losing at about 7Kg (15lbs)/month and about 10 weeks after starting massive shedding began (worst I've ever had), it took 5-6 months of shedding for it to subside but it grew back i.e. visible density at the scalp started to fill in a couple of months after...
  4. violetfluff

    Dutasteride And Finasteride, And Their Structures

    OK, I see. They wont interact to render either ineffective, I my self am sensitive to Telogen Effluvium from dietary changes.
  5. violetfluff

    Dutasteride And Finasteride, And Their Structures

    In chemistry/biochemistry a small change or 'bump' here or there on a molecule/drug can make a vast difference in how that it interacts with a person's biochemistry. Putting something as small as a methyl group somewhere could make a drug completely inactive or greatly change how the compound is...
  6. violetfluff

    Dutasteride And Finasteride, And Their Structures

    I was just speculating on a possible analog similar to dutasteride, it's not important. That would have to do with some people, supposedly, having a variation in their 5aR enzymes where it might bond more weakly with either finasteride or dutasteride. These compounds mimic testosterone in...
  7. violetfluff

    Dutasteride And Finasteride, And Their Structures

    There is nothing to indicate that they will interfere with each other either chemically or pharmacologically. As an irrelevant side note those two trifluoromethyl groups are often pharmacologically equivalent to bromine substituents so the bromine dutasteride analog (i.e. with a...
  8. violetfluff

    Dutasteride And Finasteride, And Their Structures

    For dutasteride there appears to be at least two biological pathways to eliminate the substance from the body, the first one rapidly clears it with a half-life of 3-9days which occurs for low or acute exposure. Higher doses or more frequent doses are cleared more slowly with a half-life of 3-5...
  9. violetfluff

    Dutasteride And Finasteride, And Their Structures

    I'm not qualified to say but I would guess it has to do with inhibition of hydrolysis of the amide linkage due to to steric hindrance. The tert-butyl group, in the case of finasteride, may be less effective than the p-di(trifluoromethyl)benzene group at blocking the breakage of the amide bond...
  10. violetfluff

    8 Mo Finasteride. Great Results But Shedding More Hair Than Ever.

    A high shed rate associated with male pattern baldness is due to miniaturized hairs with a shorter life cycle i.e. shorter anagen phase which results in a high turn-over rate. The hair may not even appear to thin depending on the regrowth rate and the delay between shedding and re-emergence of regrowing hair. It...
  11. violetfluff

    Thinning? Temporary Shedding? What's Happening? 30yr Old Male

    Not eating properly e.g. skipping 2-3 days/week of food have induced Telogen Effluvium in me in the past, so has dieting on LCHF, so it's quite possible but you appear to have male pattern baldness going on too going by your hair line.
  12. violetfluff

    Ot: We Can Finally Stop Demonizing Butter

    Is it as simple as a calorie is a calorie? "In normal subjects, the fat content of a formula diet in the form of corn oil and olive oil (but with constant carbohydrate and protein intake) was raised continuously up to a daily ingestion of more than 6,800 fat calories. Under normal utilization...
  13. violetfluff

    Finasteride: when will i stop losing short tiny (miniaturized) hair?

    Think about it. If you only maintain then any hair follicles which have been damaged by male pattern baldness wont get any better, or worse. This means they will be stuck in their state i.e. a short anagen phase with consequent high shed rate of such hairs. You should see no improvement in that. Yet with such a...
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