Recent content by GolDRoger

We all know you don't get any pussy, with or without hair. Stop LARPing

I think the biggest worry with PTD-DBM would be increased cancer risk due to increased Wnt pathway signalling... Would I be correct in thinking that? "Since its initial discovery, Wnt signaling has had an association with cancer. When Wnt1 was discovered, it was first identified as a...

Follica is trying to transplant artificially grown stem cells into wounded scalps, right? Choi is trying to grow new follicles, but there is no transplanting involved. A peptide blocks a certain protein interaction that inhibits wound healing (and hair growing) ability, and the body starts...

Thanks for correcting my generalizations. As for CXXC5 possibly being a "bug", I mean that in the context of CXXC5 binding with Dishevelled to inhibit Wnt pathways. CXXC5 binding with Dishevelled and inhibitng Wnt pathways would be a bug if it turned out that Wnt pathway inhibition doesn't have...

Source: http://jem.rupress.org/content/212/7/1061 Source isn't anything new, has been out for 3 months. Also was linked on this thread before iirc. Just wanted to point out how exciting this study is. The same mechanism that regrows hair also boosts wound healing.

I'm pretty sure that this is the one. I think that the peptide will work incredibly well, provided that it has been synthesized and administered properly. What Choi and his team discovered about CXXC5 is remarkable and could be groundbreaking for medicine as a whole, not just for hair loss...

For the people who are taking part in the PTD-DBM experiment, are you guys also using a WNT pathway agonist along with the PTD-DBM peptide? Also, is it safe to use a WNT pathway agonist in the first place?

Take note of the fact that they regrew hair follicles on areas where they first physically destroyed the hair follicles by scarring them. And it worked with human cells and worked well. Thick hair regrowth and lots of new follicle regeneration. That's an incredible result that is all the more...

Stop whining about useless things like trials being done on mice or the fact that new medicine takes years to be approved. EVERY new drug requires years of rigorous testing, first on animals and then on humans, in order to be approved. This study was just published in the Journal of...

It said "prominent sebaceous units suggest an associated component of Androgenetic Alopecia", with the main thing being Telogen Effluvium.

So if I understood your posts in this correctly, your choice to cease using Minoxidil is mostly due to the psychological burden of having to go through massive sheds every 6 months or so, correct? So it's going to be Finasteride that does the bulk of the heavy lifting so to speak, and Minoxidil...

House - I have a question. I'm almost a month in with minoxidil and I'm very unhappy with the shed, as my hair wasn't that bad before starting treatment. I'm contemplating whether to stop Minoxidil and just hop on finasteride, or whether to just ride this shed out. Would love to hear your thoughts on this.

Just got a biopsy done and it shows both Telogen Effluvium as well as "prominent sebaceous units". I'm going through diffuse thinning on the top of my scalp, more in the front of my scalp. Are these "prominent sebaceous units" - enlarged sebaceous glands if I understand them correctly -...

I currently have relatively minor diffuse thinning all over the scalp, as well as the sides. Could the Telogen Effluvium have caused the enlargement of the sebaceous glands? And also, are enlarged sebaceous glands typically a smoking gun for Androgenic Alopecia?

Hi guys, I just got my biopsy results in a while ago. It seems to suggest that I have Telogen Effluvium... but also prominent sebaceous units, which in turn apparently suggests Androgenic Alopecia. My doctor didn't spend much time explaining these results to me and I'm still very confused. So...