That's a side point, I think. If I understood correctly, you were originally suggesting that the next hairloss drug will be a drug developed for other diseases but one that just so happens to grow hair as a side effect; at the point of this serendipitous discovery, the drug is rebranded or otherwise used off label for hair growth. And you have correctly recognized that that was exactly the case with minoxidil, but I disagree with your placement of finasteride in the same category. As I mentioned earlier, a 5ARI's consequence on both hair and prostate growth were very well elucidated due to the studies on the 5AR-deficient population in the Caribbean. Hair growth was always expected and it is therefore not surprising that Propecia was released a mere 5 years after Proscar. In this case, the brief period of off label use prior to the release of Propecia is due to jumping the gun and off label use of Proscar currently is only done for obtaining finasteride at a lower price. So, the mere fact that Proscar was (and is) used off label offers no insight into the difficulty of finding a hairloss cure, the manner in which that discovery is made, or the field in which it is made (there are clearly non small molecule approaches such as autologous cell transplantation that show promising, if not more elegant means to cure hairloss; biopharmaceuticals are an emerging important class of drugs that do not fall into the small molecule category). And so I reject your claim about how the next hairloss drug will arrive to the general public.