Very Impressive Dermarolling And Minxodil Results - From Tressless

[theGloriousFollicle]

1.5mm is definitely deep enough, if you go too far you can damage the follice.

sauce?

 

[bucksins6x]

sauce?

Barbecue

 

[badhabiz]

Absorption of what? Peptides with heavy molecular weights? I don't think minoxidil has an issue penetrating the scalp.

sulfate minoxidil has
i think depends of the type of minoxidil you want to use
imo

 

[John Difool]

It shouldn't

Molecular Weight: 289.31 g/mol

What makes you say that?

 

[badhabiz]

It shouldn't

Molecular Weight: 289.31 g/mol

What makes you say that?

just a thought

https://www.karger.com/article/FullText/488011

"Studies in vitro with MXS proved that its efficacy is 14 times higher than MX base [4]. However, MXS has a molecular weight of 289.3 g/mol, while MX has 209.3 g/mol, a difference of nearly 40% [6]. As molecular weight is a determinant factor for the degree of transcutaneous penetration, this may present a problem for absorption of topical MXS compared to topical MX [6, 7]."

so im led to think dermarolling is particularly effective with minoxidil sulfate

 

[John Difool]

From the same article you linked two paragraphs down:
However, in addition to the issue of its higher molecular weight, MXS is naturally unstable in aqueous solution, negatively affecting its bioavailability to the hair follicle and increasing its irritation potential to the scalp. Therefore, efficacy of MXS compared to MX base for the treatment of Androgenetic Alopecia may be impaired, and the same efficacy may not be expected as in the original clinical trials with MX base.

 

[badhabiz]

From the same article you linked two paragraphs down:
However, in addition to the issue of its higher molecular weight, MXS is naturally unstable in aqueous solution, negatively affecting its bioavailability to the hair follicle and increasing its irritation potential to the scalp. Therefore, efficacy of MXS compared to MX base for the treatment of Androgenetic Alopecia may be impaired, and the same efficacy may not be expected as in the original clinical trials with MX base.

i dont want to convince you at all, i was just reporting a study, other than users opinions here

 

[John Difool]

Not at all. In fact you re-convinced me not to use MXS. Good job.

 

[rcom440]

Microneedling really does something, not sure whether it is enough to combat in a meaningful way or not. I shed almost a 100 hairs a day but with microneedling the shedding almost completely stops for one day or two after the procedure and then keeps on going as normal. I guess that's worth something though.

In my case shedding pretty much stops for a 3 days after dermarolling with 1.5mm. I don’t think I shed 100 a day. There is definitely something happening now as I see some regrow on my hairline nothing major but it’s a good sign for 2.5 months of dermarolling every 2 weeks. I had quite big shed that slowed down a week ago so I think I will have a nice regrow soon.

 

[Throwaway94]

In my case shedding pretty much stops for a 3 days after dermarolling with 1.5mm. I don’t think I shed 100 a day. There is definitely something happening now as I see some regrow on my hairline nothing major but it’s a good sign for 2.5 months of dermarolling every 2 weeks. I had quite big shed that slowed down a week ago so I think I will have a nice regrow soon.

You two are ridiculous

 

[theGloriousFollicle]

Barbecue

 

[theGloriousFollicle]

1.5mm is definitely deep eneough, if you go too far you can damage the follice.

You're just parroting broscience BS, I'm yet to see a source for this crap

 

[Ludachris Batbak]

Hey guys, can someone post me the comparison post of the Dr Pen Ultima 6 vs Derminator 2 ? I know this post was around here ..maybe 1 year ago.. i ask this because this post mentioned the needle depth of the ultima vs derminator.. on of them needs to be set deeper to get the same depth.

Since I have my new needles, I have the feeling that they do not work properly and the needle length does not match to the depth of the pen.

 

[bucksins6x]

You're just parroting broscience BS, I'm yet to see a source for this crap

 

[joni106]

So to all who do microneedling once a week / two weeks / month,
do you use something topically right after the wounding?
i use castor oil+emu oil. I started 1 moneth ago.

 

[killDHT]

So to all who do microneedling once a week / two weeks / month,
do you use something topically right after the wounding?
i use castor oil+emu oil. I started 1 moneth ago.

castor oil is too big to through your scalp.
Now I am thinking about zine ricinoleic acid.

 

[LowHairLine]

Hey @Ludachris Batbak,

you were one of the good responders - what is your situation now?
Would you mind updating with new pics? Thanks

The reply to gour Qs are below.
Good luck...

A6 Vs D2

Hey guys, can someone post me the comparison post of the Dr Pen Ultima 6 vs Derminator 2 ?

I owned both and did the mini review that I believe you are referring to:
https://www.hairlosstalk.com/intera...-studies-and-such.119653/page-13#post-1777669

i ask this because this post mentioned the needle depth of the ultima vs derminator.. on of them needs to be set deeper to get the same depth.

This only happens if you use A6 cartridges on the D2 or vice-versa -
if you use the originals, it does not apply.

Since I have my new needles, I have the feeling that they do not work properly and the needle length does not match to the depth of the pen.

You can verify the A6 unloaded needling depth as follows:
while it's running, the needles working stroke is visible under a (very) bright (flash)light -
just measure their protruding length from the plastic protector with a caliper / mm paper.

Due to damped-oscillation principles, the skin penetration will be a bit less for sure,
but it's very hard to tell by how much...

 

[newdutuser10]

Does anybody have a personal theory as to why dermarolling every other day is working better for me compared to one a week or biweekly?


Is it just over-absorption of minoxidil?

 

[joni106]

castor oil is too big to through your scalp.
Now I am thinking about zine ricinoleic acid.

Becaus of tahat i mix it with emo oil. looking for mor oil for promotion wnt.
What is zine (k?) ricinoleic acid?

 

[John Difool]

You guys are keyboard challenged.

Zinc ricinoleate is the zinc salt of ricinoleic acid which is obtained from castor oil.