Verteporfin drug induced scarless healing with new hair follicles on mice. This new founding can be really big

[hairlossisevil]

That’s not hair. They didn’t shave any of the pigs POD. All wounds contract themselves.

You do that on a human and you get a perfect rectangle of nothing but scar tissue.

 

[pegasus2]

Every scientist wants to hype their findings so they can get more funding. Always take it with a grain of salt

 

[FollicleGuardian]

You do that on a human and you get a perfect rectangle of nothing but scar tissue.

You really don’t if there is mechanical stretching. Look at FUT scars.

 

[FollicleGuardian]

FUTs are stitched up

There’s a reason for it. To not get stretches. There’s always tension. In these pigs there’s a lot of it.

 

[FollicleGuardian]

I'm going to say this one more time because I care about you bro. You gotta stop coping. It's not healthy. Maybe we can do an intervention for you on discord

Haha bro lmao <3

 

[Diffused_confidence]

They were much bigger excisions than what's remaining bald

I think that may be due to the wound being deeper in some areas. There is a diagram of the wounds and the outer layer doesn't go into the dermis it seems. Maybe that's why there is some regrowth around the border?

 

[-specter-]

I believe that at this point the only answer can come by testing the procedure on humans and seeing what happens. I have enough faith in this theory because as I said in the past I know of people who have been "treated" with herbal concoctions in Sardinia who have experienced healing from burns and wounds with a lot of hair regrowth. Now we have never managed to deal with it with the pharmaceutical companies, but if a farmer in a remote place has succeeded, I do not see why the product of serious scientific research cannot work.

 

[surfer9]

So I assume this will potentially help regrow extracted follicles/hairs.... correct?

We are not hoping we can wound a NW6 bald head, inject this drug and see healing and regrowth of a head of hair, are we?....

 

[Diffused_confidence]

So I assume this will potentially help regrow extracted follicles/hairs.... correct?

We are not hoping we can wound a NW6 bald head, inject this drug and see healing and regrowth of a head of hair, are we?....

Correct

 

[Diffused_confidence]

Found this video that is related. Can give an idea on how this would work in theory.

 

[Roeysdomi]

Found this video that is related. Can give an idea on how this would work in theory.

Lol i post that video on reddit its turn out the dr Maksim is working on a way to regenrate hair follicols by curing scars.

 

[Diffused_confidence]

OK so I read through the study. It's a dud guys. The depth of the wounds are .07 inches ~ 1.75mm and an FUT is much deeper as terminal hairs tend to go about 7mm deep. So I doubt this is going to regenerate terminal hairs but possibly velius hairs? Either way it isn't an answer to unlimited donor supply.

 

[Roeysdomi]

Found this video that is related. Can give an idea on how this would work in theory.

Smi

OK so I read through the study. It's a dud guys. The depth of the wounds are .07 inches ~ 1.75mm and an FUT is much deeper as terminal hairs tend to go about 7mm deep. So I doubt this is going to regenerate terminal hairs but possibly velius hairs? Either way it isn't an answer to unlimited donor supply.

dosent really matter if you can genrate full recovery of skin then at the end foliicels spouse to generate

 

[Diffused_confidence]

Smi

dosent really matter if you can genrate full recovery of skin then at the end foliicels spouse to generate

But can it recover at the level of subcutaneous tissue? So far they only proven recovery of sweat glands and reduction of scars on the surface. But regenerating terminal hairs? I doubt it.

This is a diagram of a terminal hair follicle. The hair lies at the top layer of subcutaneous tissue which is about 4mm deep.

 

[coolio]

That's what guys on these forums tend to miss about skin-healing progress. Regrowing skin tissue is not the same thing as creating or restoring terminal hairs.

If you lose an arm, covering the stump wound with skin is one thing. Regrowing the lost arm is something else.

 

[Diffused_confidence]

That's what guys on these forums tend to miss about skin-healing progress. Regrowing skin tissue is not the same thing as creating or restoring terminal hairs.

If you lose an arm, covering the stump wound with skin is one thing. Regrowing the lost arm is something else.

Don't get me wrong, I do hope this helps with scarring because that's the biggest reason why Norwood 3 candidates avoid transplants because they know down the road you will have to shave anyway but have scars.

If this recreated sweat glands and prevented the noticeable surface lumps from scarring then I probably would get a hair transplants down the road.

 

[glammetal]

Guys this video is publiclshed on September of 2020.They they mention that they plan to finish their phase 3 trial in about a year. So by now they should finish their phase 3 trial. However when I go at their site about this treatment it show "error 404".Does anybody know anything more about the time this will be released?

 

[DuncanOP]

That's what guys on these forums tend to miss about skin-healing progress. Regrowing skin tissue is not the same thing as creating or restoring terminal hairs.

If you lose an arm, covering the stump wound with skin is one thing. Regrowing the lost arm is something else.

But the study with pigs are related to recover of hair follicles too. Not just the regrowth skin tissue.

OK so I read through the study. It's a dud guys. The depth of the wounds are .07 inches ~ 1.75mm and an FUT is much deeper as terminal hairs tend to go about 7mm deep. So I doubt this is going to regenerate terminal hairs but possibly velius hairs? Either way it isn't an answer to unlimited donor supply.

Can you link where is was said with the study, please?

 

[Diffused_confidence]

But the study with pigs are related to recover of hair follicles too. Not just the regrowth skin tissue.


Can you link where is was said with the study, please?

Disrupting biological sensors of force promotes tissue regeneration in large organisms - Nature Communications

Humans and other large mammals heal wounds by forming fibrotic scar tissue with diminished function. Here, the authors show that disrupting mechanotransduction through the focal adhesion kinase pathway in large animals accelerates healing, prevents fibrosis, and enhances skin regeneration.

www.nature.com

Search for 0.07 and you'll find the part I'm referring to.

 

[KNemo]

OK so I read through the study. It's a dud guys. The depth of the wounds are .07 inches ~ 1.75mm and an FUT is much deeper as terminal hairs tend to go about 7mm deep. So I doubt this is going to regenerate terminal hairs but possibly velius hairs? Either way it isn't an answer to unlimited donor supply.

Vellus hairs are shallow while terminal hairs are deep, but the thing is normal hairs essentially goes from almost vellus to the deep large sexy hairs we all want so much. As long as regenerated hairs are of the normal type I don't see a reason for new hairs not being able to grow down.

Also there's proximity effects so the depth of the wound doesn't hinder changes deeper down.