UV Spectrophotometer Results:

CCS

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edited most recently:

I just looked at the graphs again.

The only dutasteride graphs that are reliable are the last dutas one (which is two pills I bought), the elite net (1 pill), and the avodart one (two pills).

The rest have too much noise to mean anything.

As for these three, they all have a saddle that starts around 250 nm, climbs a bit by 260 nm, and drops halfway by 270 nm. None of the finasteride graphs have this. That conclusively proves that the dutasteride pills do not contain finasteride.

Also, the saddle seems to be about 40% as high as the peak at 230-240 nm. They all have this peak. Both of these peaks are proportional in these three samples and are proportional to the dose, with the 1, 2, and 3 pills. That is very promising for the dutas and elitenet avodart.

Also, with the finasteride, I looked at the doses of my proscar and the hight of the main peak after shaving off spikes, and if you divide the dose by 2, you get the abs for the tall peak. It is proportional. I looked at the other finasteride graphs and they are all proportional too.

the finasteride graphs also have a low at 300 nm, about 1/3 as high as the left peak. Though there are spikes, the fincar the dash gave me is clearly real.

Well, UV is never conclusive, but the UV spectrum supports that the fincar is real.

As for the finpecia, one of them is too jagged to be used. I am bothered that the one tittled "beaner 2" has a low that is about 3/4 has high as the left shaved peak, instead of 1/3 as high. If you look way off to the right, where I cut off the graph, the absorbance rises steadily. It goes higher than that. That is because of all the white stuff. Further to the right is the visual spectrum, which starts at about 350. I wonder if some of the particulates in solution are scattering or reflecting some of the right side UV light, and the low dose finpecia has a small magnitute compared to it.
If this is the case, there should be as much or more absorption than the 2.5 mg proscar, which has 1/4 as much filler. Looking at the graphs, this is the case. The finpecia saddle is at 1.2 at the 300 nm. The proscar 2.5 mg is at 0.7. So the filler could be scattering the light.

UV light enters the tip through one fiber optic, is shined through the liquid, and enters the other fiber optic at the other end, about 1 cm away. Only aromatic compound absorb UV light, but the white particulates might scatter it. So since the finpecia has more "absorbance", it could be scattering. Since the proscar has a smoother graph, i would say it is dependable, and that if the finpecia had had a proportionately lower abs, we would know it is fake. But it is the other way around, so it could be the filler.

what is really intersting is that the blank had a few spikes of only 0.1, much smaller than the spikes on the meds. even if there were impurities, they would have round spectra too. i don't know why the meds have so many huge spikes.

I'm going to continue taking my dutas. but i think jayman is better off taking avodart instead of proscar as a back up since the price is similar and the avodart will complement the dutas, whereas the finasteride will not, if the the dutas is real.

editted more recently:

I was wrong about the dutas being fake. The difference is the large noise spikes. That means the tests are inconclusive, though in the last dutas test, and the elitenet test, the spikes were small enough to see that the graph looks like the avodart spectrum. however, aside from the hump at 270 nm, avodart looks relatively similar to finasteride, and the UV can only catch some fakes, but is not good enough to prove that a drug is real. The good news is the pills have aromatic compounds in them with the right absorbance level, which shows that whatever they are, they are not just filler.

I suspect they are real, but still want to do more tests, and see if i can do the UV again with less noise somehow, since i did get lucky with the dutas the second time.

Editted: after looking the graphs over at my leasure, i think the big spikes are just noise. dutasteride and finasteride have peaks at 240 nm on these graphs, but the dutasteride seems to have another peak at 270 nm, and it looks like the dutas does not have one there. As much noise as there is, and with the possibility of aromatic inactive ingredient, this evidence is not compelling.

Also, i must point out that these pills are not blanks. They do have some kind of steroidal compound in them that looks similar to finasteride. I need to check the IR next, for the dutasteride's fluorine bonds.

Also, the dutas in the last graph looks about right. The duprost has too much noise to tell in that graph. Maybe i can scan it again.

I'm surprised that the 270 peak is smaller instead of larger than the 240 peak.

the avodart was 2 pills, and one of the dutas was 3 pills and the other 2 pills. i think aplunk1's dutas is the one with 3 pills. The 4th got wasted in some water, and would not dissolve properly. It just made a clowd of droplets.
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A guy on here I trust mailed me avodart, which he says he got from a US pharmacy. I'll ask him if I may disclose his username.

I tested the other dutasteride capsules agaist it. Elitenetpharmacy seems to match it. The others have too much noise to tell, though one of the dutas ones I redid does look like the avodart.

I forgot what the Duprost results were, but their spectrum are saved in excell. I will post them soon when I figure out how.

As for all the finasteride pills, they all had the right spectrum, even the one from a guy who doubted his.

I did not have time to look at how much is in there, but I ground up a full proscar, half a proscar, and 3/4 proscar, and can look at their absorption to measure the others. I'll report that later. I have to give a report to my professor in 90 minutes.

The dutas was from inhousepharmacy that I bought and also from Aplunk1. All the other pills were from people I trust. I trust the guy who sent me the Avodart, but I am going to check the IR spectrum for fluorine soon, just to be safe. I'm glad I did not stock up on dutas before doing the test.

I tested everything twice, repeating the cycle, and even tested the blank twice, and tested the dutas 4 times. I'll look more closely at the saved results and hopefully find a mistake, but the UV Spectrophotometer is very good.
 
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crap. does this mean my dutas is probably n ot real? when you said elitenetpharmacy seems to match it what did you mean? their dutas does or their avodart does?
 

Aplunk1

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Thanks College!

Do you feel that there is any legitimacy in the dutasteride?

I understand that Indian law provides that the generic chemicals CAN be created, but by different processes.

I wonder if this may have skewed any generic dutasteride results.

As for Avodart, I have a new batch of Avodart. If you'd like a few sample pills (just in case you decide to do another test), you are more than welcome to have some.

Thanks again, College.

I guess, given all this, that Dutas should be avoided.

Oh, and College, I've called local pharmacies, and Costco was the cheapest for Avodart w/o insurance. Check it out.
 

chino20

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Hey man, thanks alot for doing the tests! Did you happen to check finpecia at all? Or anything made by cipla?

That's a shame about the dutas though :-x
 
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Aplunk1 said:
I understand that Indian law provides that the generic chemicals CAN be created, but by different processes.

I wonder if this may have skewed any generic dutasteride results.

i wonder this too. i find it very hard to believe that dr reddy's a publicly traded company in the US would put out a fake drug. my pictures of my blister packs and my pills EXACTLY match pictures of those on google. in addition there are many on here who have found success with dutas.

aplunk what would you say the avg price in the us for a year's supply of avodart from a us pharmacy is?

thanks.
 

Aplunk1

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JayMan said:
aplunk what would you say the avg price in the us for a year's supply of avodart from a us pharmacy is?

With or without insurance?

Without insurance, I wouldn't pay over $970 for 360 pills. Walgreens, Rite-Aid, and a few others overcharge their prescriptions. Food-4-Less, Wal-Mart, and Costco sell Avodart cheaper.

With insurance, you can expect to pay about $10-$40 per 90-day supply...

Yearly Cost of Avodart:

So, without insurance: About $950
With insurance: $40-$160


That's outrageous, given that the actual product value is maybe only a few cents per capsule.

Yearly Cost of Propecia:

About $600 per year.
 
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so your insurance covers yours?

waht do you think about my comments above aplunk about my inhouse dutas looking exactly like pictures of dutas on google? it would have to be a hell of a forging job.

college said above that dutas resembled finasteride to him? if someone was going to fake a drug why would they do that instead of just putting in dutas?
 
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i just ordered a medicalwellnesscenter script just in case

it will be interesting to see if my insurance company approves coverage for avodart. the pharmacy will check it against the list and i think it's 50/50 i get 75% of it paid for.
 

BubblyToes

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So the $75 worth of Dutas I purchased from inhousepharmacy.com and recieved last week are worthless? Damn, that's just great. I'm glad I got my Proscar prescription re-filled.
 

Felk

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collegechemistrystudent said:
A guy on here I trust mailed me avodart, which he says he got from a US pharmacy. I'll ask him if I may disclose his username.

I tested the other dutasteride capsules agaist it. Elitenetpharmacy seems to match it. Dutas did not, at all. Dutas spectrum looks more like finasteride's, but without the right side, which I think is the white powder in the 70% isopropyl alcohol.

I forgot what the Duprost results were, but their spectrum are saved in excell. I will post them soon when I figure out how.

As for all the finasteride pills, they all had the right spectrum, even the one from a guy who doubted his.

I did not have time to look at how much is in there, but I ground up a full proscar, half a proscar, and 3/4 proscar, and can look at their absorption to measure the others. I'll report that later. I have to give a report to my professor in 90 minutes.

The dutas was from inhousepharmacy that I bought and also from Aplunk1. All the other pills were from people I trust. I trust the guy who sent me the Avodart, but I am going to check the IR spectrum for fluorine soon, just to be safe. I'm glad I did not stock up on dutas before doing the test.

Since I know some fakes are in the system, and just need to varify that it is the dutas, I plan to buy my Avodart at walgreens if I can from now on. This is bull $#iT.

I tested everything twice, repeating the cycle, and even tested the blank twice, and tested the dutas 4 times. I'll look more closely at the saved results and hopefully find a mistake, but the UV Spectrophotometer is very good.

So Elitenet avodart is the real deal? I sent a sample of their Proscar to Powersam (who's used proscar before) and he says even though its packaged as proscar it's definately not merck proscar - weird lettering on blister pack, spelling mistakes on the leaflet, etc...
 

Cassin

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collegechemistrystudent

With all due respect, what exact qualifications do you have to be testing these chemicals besides your own confidence?

No offense, but if your throwing this out I think it's only fair that you explain your qualifications.
 
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dr reddy's and cipla and ranbaxy have to use different methods to make the dutasteride. indian law recognizes the patent on the procedure to make the drug but not the drug itself. so if the drug is of slightly different composition then that could affect the results.

Inhouse is a very reputable pharmacy and Dr Reddy's is a very reputable manufacturer. It seems like a pretty solid supply chain to me don't you think?
 

Cassin

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JayMan said:
dr reddy's and cipla and ranbaxy have to use different methods to make the dutasteride. indian law recognizes the patent on the procedure to make the drug but not the drug itself. so if the drug is of slightly different composition then that could affect the results.

Inhouse is a very reputable pharmacy and Dr Reddy's is a very reputable manufacturer. It seems like a pretty solid supply chain to me don't you think?

JayMan...we're starting to agree more and more. Most companies are in the business of making money the honest way and until CCS makes it clear how he is qualified with evidence, I would ignore his post.
 
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Cassin I've spoken with InHouse a couple of times in the past hour to a manager there and they have informed me that they buy from a wholesaler in India and the wholesaler has a DIRECT link to Dr. Reddy's. The manager was unaware of how UV spectroscopy works but he assured me that the Dutas would work exactly the same as the Avodart. I even asked him straight out if I should buy the Avodartt instead which is the more expensive drug and he stated that that would be stupid because I can save so much money with the Indian generic Dutas. He then offered to e-mail me some info about the quality of Dr Reddy's products and all the great work they've done with AIDS generics.

I am now a bit reassured about Dutas's quality.
 

hairwegoagain

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Moral of the story:


1) Don't take medical advice from someone who hasn't even passed the first two years of undergrad

2) Don't buy drugs from a filthy 3rd world society that wipes its *** with its bare left hand.

Cassin - in what area of the metroplex do you live?
 

Cassin

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hairwegoagain said:
Moral of the story - don't buy drugs from a filthy 3rd world society that wipes its *** with its bare left hand.

I don't mean to keep harping on this, but I simply cannot accept the results of one guy in college. I am sure CCS means well..........

hairwegoagain said:
Cassin - in what area of the metroplex do you live?

N-Dallas.

/P1
 
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"In fighting AIDS, Brazil's generics makers have gotten much ink. But according to data from IMS Health Global Services, India's active pharmaceutical sales by volume are about triple Brazil's. India gets efficiencies from huge volume. Quality is high; more than 25 of the country's drug plants have been inspected and approved by the U.S. Food & Drug Administration (FDA). The country's chemists are innovative. "


http://www.forbes.com/global/2001/1210/026_2.html

"Dr. Reddy's shipments of generics to the U.S. should zoom to at least $65 million this year, from $5 million last year. Next year: $100 million. The company ships active ingredients in bulk to such generics heavies as Teva and Ivax. A dozen more of Dr. Reddy's generic applications have received FDA approval.

The Indian leader in the U.S. generics market is Ranbaxy Laboratories in New Delhi. Merrill Lynch estimates that Ranbaxy's U.S. revenues will quadruple from last year to $269 million by 2003. Ranbaxy also proved its R&D skills by licensing a one-a-day Cipro delivery system to Bayer, on which it will earn $65 million in licensing fees. "



I honestly think that for every 1 person online who posts about how their Dutas didn't work there are probably 20 who are using it for hair loss who have seen great results from it. There are plenty on here who use it for Inhouse who swear by it.

Now college did say in the first post that the dutas looked similar to finasteride. we should be clear about whether or not it is finasteride or dutasteride or just a total fake sugar pill.
 

hairwegoagain

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Cassin said:
N-Dallas.

/P1


Very good, Las Colinas area here. Born and raised in N. Dallas.
 
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