@Trichosan I already asked you to help us out and translate the article but you don’t answer. This is sad.
Why your wife can’t read the whole article and collect and summarize the interesting facts(we don’t need a translation of every scientific sentence or other blablabla - only filtering important business facts. That should take 10 minutes work for her)
Is there some informations given:
- when will the human trials start?
- about commercial plans?
I would be glad if you answer us...
Ok, so i used a different translation tool and here is what i got. It translates some of the parts DeepL missed out on giving us a few more details, but it makes less sense overall.
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Leader in "hair and tooth regeneration". clinical research on regenerative medicine to regenerate human organs will begin soon. The target is the hair and teeth. Jartcosm Asako Tsukazaki, LN Oka Studio Takashi Tsuji, Takashi, Team Leader, Center for Frontier Biosciences, RIKEN Transplant. Unlike AS Ruruya, it is a new approach based on the latest regenerative medicine. Takashi Tsuji will lead the organ guidance research team at the Center for Biological Function Sciences (Koreto City) of RIKEN. As researchers in Japan and overseas are trying to overcome the barriers the practical application barriers of regenerative medicine, Tsuji's research has great potential for widespread application, and is attracting attention. What makes Tsuji unique is that it is not the reason why researchers have long been a faculty member of RIKEN's team, but have been working in the states for the academic year. I am from a national university in a rural area and have no experience studying abroad. He quit his job as a researcher at a pharmaceutical company and went on to a doctoral course at the graduate school, but was frustrated. Good news for men with different hair. Using the technology of regenerative medicine, he got a job at a Fusafuno pharmaceutical company, but the drug candidate he had been studying was discontinued. It's a life of a researcher with a new twist. In 1962, I was born in Mino City, Gifu Prefecture. The organisation will soon start a clinical study to regenerate hair follicles, 10 kilometers away from the city center. This is the world's first regenerative medicine for body organs. The cells that are the origin of the collected hair are cultivated, and a large number of times are increased (organ root line that creates hair).
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Tsuji, helped his family business from the 4th grade. The store was a sales shop, so my job was to collect money. My father, who did not attend ordinary high school, wanted us to study hard and live better lives. Tsuji had a vague idea that he wanted to become a doctor and to serve his country. JPS was a researcher of cancer cells. After the second year of the master's program, he became a researcher at the Central Research Center, which was transferred to Yamanouchi Pharmaceutical (now Astellas Pharma), aiming to contribute to society through medicine, and was thoroughly trained from research manners to how to write reports. After that, Yoshiyoshi Furuichi, who will be the executive officer, argued that "it will not be successful unless we develop a country that can only work on the task in front of us and do research to become the next seed of rice." Science that only comes to you. At the time when it became known that the ES master drug article by S°4 Udo DNA was cut off after leaving the school, the outbreak educator Setsuto Okada's "Life in the test tube" was recommended by the teacher. I read and entered the Faculty of Science, Niigata University, which chose the path of biology, but there is no latest lecture on genetics and molecular biology, and practical training is also a high school lesson such as sketching onion epidermal cells. After spending some time reading a technical book, when I was in the 4th grade, I met Soumi Ii, who I started as a professor from the Tokyo Metropolitan Institute of Clinical Medicine, and knowledge of chemistry is indispensable in a bio-pharmaceutical company. It was a complex that I was from the department of biology and ignorant in chemistry, but I told myself that "I honestly know that I do not know what I do not know, and learn in the field," I absorbed myself in research. After 3 years, I could see the surroundings. Good work requires a research philosophy. I want to do science that is not JA to my society," and think of obtaining a PhD. I was advised to study abroad at company expenses, but I retired to cut off my way out. The doctoral course was Shunichi Nakamura of Kyushu University.
The up-and-coming S Kankyo that discovered the breeding factor "HGF" was also attractive. Tsuji was a little shy at first, but he is also an older person, and eventually he was assigned to the practice of running the laboratory. The experience of working people came by researching graduate and undergraduate students, allocating and teaching joint research with medical schools and companies. The laboratory was full of tension and finger-Spartan, reflecting Professor Nakamura's aggressive personality. Tsuji discovered the gene for HGF and realized how interesting the research was. It was also attractive to send Shimori to the world. Regulatory figure that suppresses hepatocyte proliferation SS Discovered in the second year given a national theme. The paper was published as the first author in a leading scientific journal. He continues his research on holidays and late at night, becoming a laboratory. I felt the distance between the laboratory management and the research policy of P Nmura. I intended to do my best, but is it the limit? The future as a researcher who gave up his PhD and left the laboratory with disappointment broke off, and the . After going around Japan's Marine Research career route with the help of my fellow lab members, I finally returned to my alma mater Niigata University. Kazuhiro Mori, the successor to Mitsui, accepted me as a research student. Financially, the junior female at Kyushu University, who I was dating with, gave me the Fukuoka S next day. When I was in my second year in Niigata, I married this woman. Mori's research theme was cells of blood cells, especially hematopoiesis. If you look at how blood cells are created from stem cells in an environment that mimics the environment of bone marrow, you can see the origin of the life-rich wealth S. After this experience, in the 3rd year of the Ph.D.
After the doctoral course, he started working for Japan Tobacco Inc. (JT) in the year, when he started to use stem cells for treatment, that is, regenerative medicine as his lifework. I was assigned. Therefore, I quickly got along with Yasuhiro Kajiwara (now a professor at Osaka University) who joined the company one year earlier. According to Kajiwara, who is three years younger, Tsuji felt he was older. Although the common points are also emphasized, JT has written two hematopoietic stem Cells papers, which has become popular.. At the University of Science, I was also in charge of lectures for non-specialized subjects such as pharmacology and physiology for undergraduate students. In my private school, I was blessed with research funds and the students were serious. However, there are many people who think that almost 0 people a year in the laboratory|S will be able to do S without having to supervise more than 0 students if the graduate school is included in the distribution.” In my research, I was in contact with Otsuka Kagaku, a colleague from the JT era, who is a sponsor of JS Tsunagata S, who has made an important encounter with S. Kajiwara, who specializes in glycoengineering, made a joint research with Otsuka Chemical Co., Ltd. For the biological evaluation of the fungus that was synthesized by Kajiwara and bound to a sugar chain, Tsuji became Gangawa and RriA, and the first endowment course at Science University was set up at Otsuka Chemical. If hematopoietic stem cells that Niigata University had been working on could be made into a cell drug, it would be a therapeutic drug for leukaemia. However, the upper management of the company was transferred to the University management, where it was decided that the development would be postponed due to the risk of infection of humans and non-S-like artifacts.
I was not absorbed in research and education. I felt enthusiastic and exhausted in the Kyushu University Sulta style laboratory, but I faced the pressure from the height of PARAJm to become a leader and the difficulty of running a laboratory with many men J ° "When I went to the ED field, I felt painful about Professor Nakamura's feelings of mission and loneliness. I went fishing in the direction of Izu, and bloomed for fishing and research discussions. A year later, Kajiwara moved to Yokohama City University by moving to the JT Pharmaceutical Research Institute (Yokohama City), but the exchange Tsuji was disappointed with the newborn baby's winning zone.Tsuji sent JT who worked for 7 years. I wanted to get a job from the university.” J Ji S, Toki University of Science received a recruitment of faculty members for regenerative medicine and became an assistant professor in 2001. In the field of regenerative medicine, where patents are the specialty of companies rather than papers, the aim was to regenerate a three-dimensional device. Large and complicated organs such as the liver and kidneys are highly difficult. If organs are created according to the same biological principle and teeth that do not come to life closely to the gyrus in the body surface (the blood of the crotch) and hair blood stem cells proliferate in vitro, If you can help the teacher, you can easily set up an experimental model
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He had neither knowledge of tooth development nor research experience. In the second year, Kazuhiro Eto, who was the vice president of the Tokyo Medical and Dental University, introduced Professor Shohei Kasugai of the Department of Implantology. Kasugai, who was consulted by Tsuji, said, "I wouldn't be able to get S with a cloud-grabbing distance." In 8 years, when this tooth seed was transplanted into an adult mouse, the tooth with blood vessels and nerves regenerated. In 19 years, when it was planted on the part where the tooth of an adult mouse was missing, the tooth grew in about a month more S. Succeeded in completely regenerating teeth that can be engaged and feel pain. Kasugai hates Tsuji's sense of research. 2 years 2 also succeeded in hair regeneration from the SA shape. Hair grows at regular intervals, so in adult teeth, which can form only two types of stem cells required for organ regeneration, tooth seeds can be made only from the history of milk teeth or permanent teeth. In order for adults who have lost teeth to regenerate teeth, they must search for stem cells that become teeth, which is a barrier to practical use. %% of the time, Tsuji received the support of Otsuka Chemical and founded a venture company, Organ Tech Heroes. In order to put Tsuji's technology into practical use, it is required that JSV S patents, which are the organ primordial method, have been collected. I received a pre-application transfer of a patent from the University of Science and needed a box (company) to keep stock.
AJ Tsuji learned the principle of tooth generation and exchanged opinions, and he said, “Tooth seeds” I am convinced that it will be regenerated from "°". Totototo grows and regenerates the original material (seeds) that is the basis of separation. Organisms are regenerated and the sensitivity of Pukor AK research is clear. In the development stage, the fetus AJ, which is a developing stage, is made up of stem cells that form the necessary organ seeds and grows into organs. Tsuji extracted the tooth history, which was determined to become a tooth in the future, from the fetus of a mouse and separated into epithelial stem cells and mesenchymal stem cells. These two types of stem cells were made into a high-density two-layer structure to regenerate "tooth seeds". This method was named “Organ Primitive streak Method”, and it led to the success of organ regeneration thereafter. The company was established for the first time as a 1008 subsidiary of Otsuka Chemical. Regarding the provision of R&D funds, Sadanobu Tobe (currently Otsuka Foods Director), who was the president of Otsuka Chemical, had a strong opinion. Tobe is overwhelmed by Tsuji's hot valve that he met for the first time.
“I can understand the words of the manager, and I have a sense and idea about the seeds that a company wants. It may be an appropriate role if it is a bridge with a company.” Since he was a company with good presentations, Tsuji has been able to persuade his boss in the words of the owner to hang his heart. With H as KAN, we thoroughly implement business manners such as greetings, compliance with promises, and tidying up. From the belief that a person is a researcher and is a member of society in R. Mayumi Murofushi, an assistant at RIKEN, was a student at the University of Science, saying, "Many people are unable to greet people, and many of them (in Tsuji's belief) can feel empathy invited to RIKEN. Sasai's death and death after academia, Tsuji joined RIKEN in April 1st, but Sasai lost his life in the month of this year as he was blamed for research fraud over STAP cells. Although Tsuji's morale of the best leader P was lost, and Tsuji tended to be a while ago, the mission entrusted by industry-academia collaboration S'J R R Sasai was completed in 5 years. RJA is attracting companies to the "Integrated Collaboration Innovative Am Building" The two companies gathered only through joint research with Tsuji, and the external funds acquired by S reached 10% of the total joint research expenses that RIKEN received from the companies. .. It is also an initiative aimed at the pre-war RIKEN that can be operated independently. Aiming at the practical application of regenerative medicine for hair follicles RIKEN and Organ Co., Ltd., which has been approved as an e-love launcher that applies the seeds, formed a tie-up with Tsuji, who resonated with R°moriism at Kyozeto. , Won the contract directly with the founder, Kazuo Inamori, and won the contract. Pioneered the world's first artificial skin for evaluating functionality. As the trend of banning animal experiments progresses, it is drawing attention as the next-generation artificial skin. "Hair Diagnosis" is aimed at commercialization of the law. RIKEN promotes advanced research, 20 organizations such as organ Co., Ltd., which originates in collaboration with private companies, and Yahoo established Consortium A, and joint research has started. About 100 hair follicles collected from 1 scalp.
Cultivate to produce more than 5,000 hair follicles, equivalent to 10,000 hairs. In an experiment in which this was transplanted to a mouse, hair was regenerated and regenerated for a lifetime. There are great expectations not only for androgen alopecia but also for treatment of intractable alopecia such as congenital alopecia. On the other hand, for the regeneration of teeth, we are developing a next-generation "hybrid implant" with Kasugai of Tokyo Medical and Dental University and Masamitsu Oshima, an associate professor of Tokushima University who is a disciple of Tsuji. Treatment, which connects artificial teeth to alveolar bone to compensate for tooth loss, is widely used, but it cannot be said to be a cure. The artificial tooth is connected to the alveolar bone through the human HS periodontal ligament to reproduce the same physiological function as a natural tooth. Artificial teeth do not become caries and have the advantage of organ regeneration while strengthening their functions. It has been successful in experiments on dogs with strong success, and is aiming for early commercialisation. Tsuji, who is particular about useful research, has consistently pursued social implementation. "Innovation from innovative basic research will lead to the development of health and medical care in Japan and the promotion of Japanese industry. Its realization is its mission." There is a total of endless dreams = honorifics omitted. After working as a reporter for the Yomiuri Shimbun, Asako Tsukazaki became independent. Many authors in the medical field. Master of Science, University of Tsukuba and Tokyo Medical and Dental University. Leading authors: "Japanese medicine that saved the world" "Japanese scientists who challenged new drugs"
