Samumed Sm04554 Results Normalized To Baseline

franzliszt

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I don't see this as a stand alone treatment, when combined with other meds the result will likely be better than the phase 3 results. I'm not looking for a miracle cure, just a minoxidil alternative, that hopefully won't make me feel 10 years older.
 

Pigeon

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I don't see this as a stand alone treatment, when combined with other meds the result will likely be better than the phase 3 results. I'm not looking for a miracle cure, just a minoxidil alternative, that hopefully won't make me feel 10 years older.
Sure, if this will only give maintenance and maybe a little regrowth without any (serious) side effects, I would consider this a huge success.
 

Anatman

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I don't see this as a stand alone treatment, when combined with other meds the result will likely be better than the phase 3 results. I'm not looking for a miracle cure, just a minoxidil alternative, that hopefully won't make me feel 10 years older.
this is what i wish for. just an alternative to minoxidil and finasteride, which hold the hair that I still have and maybe make it even thicker. that would be enough for me.
however, phase 2 looked promising and still beat minoxidil and finasteride, at least on paper. So is it not enough on its own together with microneedling? we will only know after the results of phase 3.
it is still painful to see that it always seems to fail in phase 3. The previous speakers are right. there are clear inconsistencies that should make us all skeptical.

@Piegon
I totally agree with you, but the question still remains how expensive it will be and whether the results will allow a release.
after all, minoxidil and finasteride are not expensive (10 euros for 1 month of minoxidil in Eu and 30 for finasteride per month) and the market is unpredictable.
 

trialAcc

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Interestingly enough, BioSplice just posted very positive results for their phase 2b Lorecivivint trial that ended 9 days prior to the Androgenetic Alopecia trial as well as their phase 1 solid tumor trial that ended before both of them.

The argument that they would have published positive results already seems to be false judging by this release. Perhaps they could still have a surprise for SM04554? They did rename the compound to an actual drug name on their website.
 

5minutesbeforemiracle

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Interestingly enough, BioSplice just posted very positive results for their phase 2b Lorecivivint trial that ended 9 days prior to the Androgenetic Alopecia trial as well as their phase 1 solid tumor trial that ended before both of them.

The argument that they would have published positive results already seems to be false judging by this release. Perhaps they could still have a surprise for SM04554? They did rename the compound to an actual drug name on their website.
Bruh, you tryna give us hope again? :')
 

Pigeon

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Biosplice Publishes Successful Clinical Trial in Knee Osteoarthritis


SAN DIEGO, April 26, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (“Biosplice”), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today the publication of its successful Phase 2b knee osteoarthritis clinical trial data in Osteoarthritis and Cartilage. In this 24-week clinical trial, Biosplice’s groundbreaking knee OA drug candidate, lorecivivint, met primary endpoints of Pain NRS (daily pain measurement) at both 12 and 24-week timepoints. As in previous trials, lorecivivint appeared safe and well tolerated.
 
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Anatman

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Interestingly enough, BioSplice just posted very positive results for their phase 2b Lorecivivint trial that ended 9 days prior to the Androgenetic Alopecia trial as well as their phase 1 solid tumor trial that ended before both of them.

The argument that they would have published positive results already seems to be false judging by this release. Perhaps they could still have a surprise for SM04554? They did rename the compound to an actual drug name on their website.
Thanks. Now i have Hope again. :/
 

byebyehair

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Interestingly enough, BioSplice just posted very positive results for their phase 2b Lorecivivint trial that ended 9 days prior to the Androgenetic Alopecia trial as well as their phase 1 solid tumor trial that ended before both of them.

The argument that they would have published positive results already seems to be false judging by this release. Perhaps they could still have a surprise for SM04554? They did rename the compound to an actual drug name on their website.
The renaming of the drug happened two some time before the renaming of the company. (according to a comment on hlc2020)
 

trialAcc

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Bruh, you tryna give us hope again? :')
I just think that it is worth noting that they proceeded to change their name and actually had positive news to report despite a re-brand and CEO change. Most people here (myself included) completely wrote them off as soon as this happened.

The Androgenetic Alopecia drug was still a footnote in their presser, so I'm assuming it will still have weak results but you really never know.
 

Jimmerson

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Maybe it's dead, maybe it's not. The only thing we know for sure is no company cares about hype on forums. Maybe they release results when they plan to go for more vc funding
 

JealDeal

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Does anyone know the medical Congress schedule for 2021 ?
I would assume it means results are decent somehow.
 
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