hanginginthewire
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Why do you consider it good? Seems like somewhat of a delay, right? I’m genuinely asking. Outside of them cancelling the project, what would you have considered bad news?
Puretech Health - 2017 Annual Report (2018-04-16)
- Thread starter Noisette
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Why do you consider it good? Seems like somewhat of a delay, right? I’m genuinely asking. Outside of them cancelling the project, what would you have considered bad news?
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Yea it ain't great news. I'm not unhappy with the announcement or anything but it is kind of irritating.
To be honest, im a tired of the economy of words.
Yeah i know sharing too much data can affect negatively in many ways: people anxiety, competitor awareness, stock value, etc.
But reading those Puretech Health reports always leave us the feeling they are somehow downplaying the importance of Follica.
I partially blame this to the hipocrisy that still exist with baldness. I fear that for some board members and investors an Androgenetic Alopecia treatment might be perceived as unnecesary vanity compared to other affiliates therapeutic targets
@That Guy @occulus i would really appreciate your insight on this
Yeah i know sharing too much data can affect negatively in many ways: people anxiety, competitor awareness, stock value, etc.
But reading those Puretech Health reports always leave us the feeling they are somehow downplaying the importance of Follica.
I partially blame this to the hipocrisy that still exist with baldness. I fear that for some board members and investors an Androgenetic Alopecia treatment might be perceived as unnecesary vanity compared to other affiliates therapeutic targets
@That Guy @occulus i would really appreciate your insight on this
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Thanks, didnt really follow this follica so please excuse me for dumb questions. So, can I say that, at this stage, they are testing for a protocol (wounding by device + approved drugs) rather a newly developed drug ? I used to think their "compound" is something new and thats was why it took them so long.
Then, how will it look like if it is released, I mean, can we just buy the device and do ourselves or will we need a trained physician to wound us ?
They are doing preclinical work for a new compound and working with existing drugs.
The first iteration of the treatment will be approved drugs only with a "smart" applicator + Skin disruption device
Regarding the wounding device, its meant for professional use. You will have to go to a dermatologic clinic or a hair transplant Doctor.
They have far more valuable things in their pipeline.
Not the answer people here want to hear, but it's the truth. The rest of their products are far more relevant to the medical world than hairloss. Of course they downplay it; it's not going to be their main moneymaker mainly because of subverted shitheads that embrace mediocrity.
@hanginginthewire
The optimization study will end in a few months, leaving them to the pivotal soon after. Good news.
Know what would be bad news? If they still had yet to begin the optimization.
Don't forget that downvote.
H
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Can't complain at least they're making video games for depression.
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As far as I can remember, they had set a goal of commencing the phase III trial in the second half of 2018.They have far more valuable things in their pipeline.
Not the answer people here want to hear, but it's the truth. The rest of their products are far more relevant to the medical world than hairloss. Of course they downplay it; it's not going to be their main moneymaker mainly because of subverted shitheads that embrace mediocrity.
@hanginginthewire
The optimization study will end in a few months, leaving them to the pivotal soon after. Good news.
Know what would be bad news? If they still had yet to begin the optimization.
Don't forget that downvote.
Now it's set back for first half of 2019.
Yes, that is really good news.
Delusion, convince yourself.
I'm with you. It's not good news by any means.
Baldybald1
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I mean delay for few months is acceptable and reasonable, I don’t see it as a big deal
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"THE DOGMA WAS THAT YOU WERE BORN WITH THE TOTAL NUMBER OF HAIR FOLLICLES THAT YOU WERE EVER GOING TO HAVE. THEIR LOSS WAS CONSIDERED PERMANENT. NOW, WE KNOW IT'S NOT."
- Dr. George Cotsarelis
this is my favorite quote of all time...
far ahead "GET TO DA CHOPPA!"
- Dr. George Cotsarelis
this is my favorite quote of all time...
far ahead "GET TO DA CHOPPA!"
Holy hell, there is some serious ignorance on display in this thread.
"not good news"??? Their timeline that they gave with the optimization trial finishing up and final trial beginning in 2018 was a PROJECTION. It was not a deadline.
Trials take a long time to complete and a huge coordinated effort across many different groups: Clinicians, statisticians, finance guys, corporate management, government reps, patients etc... are all involved. Delays happen as a matter of course. Trials are not easy to implement and delays are expected by anyone who has even the remotest idea of what's involved. That their projection was slightly off by a few months is not anything to be concerned with. They're on course.
What should people be taking away from this update? That they haven't canceled the program and are actually starting a phase 3 trials. This is huge and by far the biggest news this site has had in the nearly 16 yrs i've been on the forum. It indicates that they have had success to date. Enough success to warrant dumping a boatload of money into running a phase 3 trial. Puretech are venture capitalists, they have no driver except profit. They could have easily earmarked that money for one of their other programs. That they decided to put it towards phase 3 for Follica is amazing. As someone who's been here a long f'ng time, and seen promising treatments come and go, this is great news. We may be inside of 2 yrs from a new, desperately needed treatment.
Like everyone, i wish it were coming faster. But, things are what they are. Just be happy that we have something real on the horizon and that's it's not a stupid lotion or a proprietary blend of branched chain amino acids that promise to give dramatic results. I've seen enough of that sh*t to last me a lifetime.
Follica, Samumed, Breezula, Tsuji, Shiseido, even Histogen which in my opinion is crap, etc etc ALL ALIVE and starting or planning their last trials before commercialisation.
I've been reading hairloss forums enough to realize how different things are from the early days of Aderans or Intercytex hype, the within 5 years and stuff.
All that said, NW5 - 7s should only pay attention to Tsuji hair regeneration tech.
Cotsarelis himself said Follica wont be by any means effective for aggressive baldness cases, he even talked about a "point of no return" for hair follicle miniaturisation.
I've been reading hairloss forums enough to realize how different things are from the early days of Aderans or Intercytex hype, the within 5 years and stuff.
All that said, NW5 - 7s should only pay attention to Tsuji hair regeneration tech.
Cotsarelis himself said Follica wont be by any means effective for aggressive baldness cases, he even talked about a "point of no return" for hair follicle miniaturisation.
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lol read what I posted above. cotsarelis also said the opposite. (see follica website)
anyway norwoods don't mean everything. They are just patterns of the actual hairloss/coming hairloss. Sometimes a norwood 5 pattern can actually regrow more than a lower norwood who has slick bald temples. It always depends on the degree of miniaturisation/density. for example If a new treatment(maintenance/fair regrowth) comes on the market next month I would rather be a diffuse 5 norwood pattern than a norwood 2/3 because basically this would mean it's a cure for diffuse but for the norwood 3 he might have maintenance but will have a hard time to regrow hairs and he maybe will need a hair transplant. Thats in the case of maintenance/fair regrowth new treatment, but if the cure comes(regrowth all lost hairs) then that's another story...
Yeah i know, but thats just marketing referring to neogenesis occurring in good responders.
This is taken from one of his latest interviews, couple years ago:
"Cotsarelis says that in gauging future prospects for alopecia treatment, it’s important to have realistic expectations. “I’d hate to use the word cure, because I don’t think male-pattern baldness can be completely reversed,”
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Baldybald1
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And remember, cots himself said back in 2012 that a treatment may come after 5 years but a cure needs around 10 years to be available. What if RAIN is the cure that may be released in 2021-22 ? ( cure here means a full regrowth of hair with continuous usage of RAIN to maintain
I think you need to review the new data Follica is based on.
Even their marketing states 3-4 plus drugs effect.
Follica has good potential but cure is another thing.
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I thought the whole deal is about "follicle neogenesis"??!? aka creating new follicles and and a point of no return shouldn't exist by that mean.
The last time I've checked, especially thanks to Noisette, was that this could also create and somehow repair old scars from FUE/FUT areas and therefore at least lead in "some" new follicles even in those fucked up areas.
Wondering what happened that this should have changed or was I totally wrong on this?
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ye it was a wise choice he used "completely" because I also think you cant regrow a juvenile hairline and at some point the mature hairline will be there.. but when you see amazing regrowth when people use extreme regimen this is a proof you can still regrow a good amount of hairs (lets say regain a decent norwood 2) even when you were in norwood cemetery.