PDRN, an unknown powerhouse for androgenic alopecia

[Tom4362]

Folks for those who want to try I strongly encourage you to buy one of those digital microscopes to take pictures of the scalp. This seems to work by improving an underlying scalp problem, which I bet all male pattern baldness have. I have posted on that before. If you see an imporvement in scalp after 6 weeks then you know what to expect hair growth wise.

Attached a picture of my scalp condition. Compare it with the donor side (mine too) and you can tell what the problem is. These yellow dots have been discussed as common finding in the literature.

Is there any microscope that you recommend?

 

[ElToso]

Placentex 10% Soluzione Cutanea Cicatrizzante 10 Fiale 3 ml eFarma.com

Placentex 10% Soluzione Cutanea si usa nelle patologie del connettivo su base distrofica o distrofico-ulcerativa: cicatrizzante, antidistrofico.

www.efarma.com

this should be better than cream right?

 

[John Difool]

Did you try farmasia loreto gallo or superhumanstore? Their vials are like 12 euro instead of 90.

Okay. Thanks. Do you have a link to that study with injections?

 

[waynakyo]

Is there any microscope that you recommend?

I got this one

https://www.amazon.com/gp/product/B07PVMRZQH/ref=ppx_yo_dt_b_asin_title_o09_s01?ie=UTF8&psc=1

Cheap. works well. You just have to be patient when focusing on follicles, clearly at 50X to 100X your hand moving will blur, so you got to keep the hand as still as possible and snap many shots.
once you get the hang of it, it works beautifully.
I think in any scalp treatment something like that is needed to gauge improvement.

 

[FollicleGuardian]

Placentex 10% Soluzione Cutanea Cicatrizzante 10 Fiale 3 ml eFarma.com

Placentex 10% Soluzione Cutanea si usa nelle patologie del connettivo su base distrofica o distrofico-ulcerativa: cicatrizzante, antidistrofico.

www.efarma.com

this should be better than cream right?

Yes

 

[FollicleGuardian]

Okay. Thanks. Do you have a link to that study with injections?

Here you go:

https://www.orlandohairrestoration.com/hair-restoration-orlando/docs/Therapeutic-efficacy-of-autologous-platelet-rich-p.pdf

 

[CastorTroy]

PDRN Hair Loss Treatment | Pn cell vitoxidil pdrn for hair growth

Pn cell vitoxidil contains Polydeoxyribonucleotide that stimulates hair growth by revitalising the hair follicles and stimulating blood circulation. Improves scalp problems and increases thickness and fullness of hair throughout. Buy online now

www.gangnamstyle-shop.com

this hairless product supposed to be used before dermaroll apparently has it in there

 

[Will Be an Egg in 5 years]

Could this work even without micro needling?

 

[FollicleGuardian]

PDRN Hair Loss Treatment | Pn cell vitoxidil pdrn for hair growth

Pn cell vitoxidil contains Polydeoxyribonucleotide that stimulates hair growth by revitalising the hair follicles and stimulating blood circulation. Improves scalp problems and increases thickness and fullness of hair throughout. Buy online now

www.gangnamstyle-shop.com

this hairless product supposed to be used before dermaroll apparently has it in there

That one will work fine

 

[FollicleGuardian]

Could this work even without micro needling?

Only a fraction of the nucleotides will absorb, so go with needling or dmso

 

[John Difool]

Polydeoxyribonucleotide is a DNA mixture with molecular weights ranging between 50 and 1,500 kDa, The higher range makes it seem unlikely to penetrate the epidermis.

 

[FollicleGuardian]

Polydeoxyribonucleotide is a DNA mixture with molecular weights ranging between 50 and 1,500 kDa, The higher range makes it seem unlikely to penetrate the epidermis.

There is C-PDRN which is only low kDa nucleotides. Do you think these will be just as effective? Maybe do injections 3-4 times per week, and the rest C-PDRN could be an idea.

 

[pegasus2]

1,500 daltons is no problem with microneedling.

 

[Selb]

1,500 daltons is no problem with microneedling.

Would this absorb well with a 0.5mm roller? I’m guessing application of the the cream/solution pre-microneedling

 

[Selb]

I love how you guys never stop working on this baldness thing. At least there are possibilities but XY's love tinkering and it is the puzzle just as much that many of us like. MtF's are like that with breast growth too and nothing works to increase them try though they might which makes me happy since I don't need any competition.

It’s a bit strange because you’d think that breast development would be guaranteed but I guess some want more than half developed gyno.

I’m looking into selective estrogen antagonists for topical use on the scalp. If we can achieve estrogen dominance in the follicles without messing with serum estrogen too much, we can achieve a better growth agonist than minoxidil.

The problem of course is that we don’t have that smart of a drug delivery system for these solutions. It makes me wish I had majored in bio chem.

 

[BaldAsshole]

What would you guys do if Goddess gave you a revelation that you would be ten times hotter as a female? I am/was mostly straight but once I pushed through the shame and humiliation, it got really good being Janey. For XY's with good facial genes, I can make anyone more attractive but you have to want it. Hair is not life but it's pretty damn close but being hot again after 30 years is mind-blowing. I haven't had any surgery but I will say that it is expensive being me!

Dude, don't derail the thread. We are talking about Polydeoxyribonucleotide here; I care not about your breast and your delusional sh*t about being attractive.

 

[FollicleGuardian]

Would this absorb well with a 0.5mm roller? I’m guessing application of the the cream/solution pre-microneedling

Yeah, even a 0.25 mm roller would do it.

 

[whatevr]

@whatevr What's your opinion on this?

Has a lot of beneficial properties on paper. Worth trying? Certainly.

At this point however, I refuse to get hyped up about anything. Too many disappointments throughout the years.

 

[Stating facts]

Also, nevermind. The vials aren’t expensive at all. Like 20 euro for 10 vials. So about 4-8 euro per month.

Placentex fiale 10% 0.75mg 3ml Soluzione Cutanea 10 Fiale

Placentex fiale soluzione cutanea, come si applica, prezzo in offerta da farmacia Loreto...

farmacialoreto.it

how to dilute the concentration in the vials? I think it is strong in comparison to the cream.

 

[FollicleGuardian]

how to dilute the concentration in the vials? I think it is strong in comparison to the cream.

5-10% DMSO+Ratio 1:1-> Ethanol, PG, I think it should be soluble in those.