Kintor has started Phase 3 trial in China for Pyrilutamide

[RagnarLothbrok]

And fwiw im salty because every thread is derailed by retards claiming nonsense lately when this forum is the only decent source left for hair loss research information that isnt Reddit teenagers

Sadly this forum is turning into yet another frustrated incel echo chamber soon since no moderators are bothering to protect it.

 

[Seeñor Pelitos]

You literally said people should know if Pyrilutamide works right away based on your broscience about RU. I wonder why are they doing months long 3-phase trials if they can know right away?

Maybe because hair growth doesn’t happen until a few months in. Hair loss reduction happens a lot sooner but I don’t think they report that. I do believe products work immediately but you just don’t see results right away. In a letter of weeks some see big sheds while others see a slowing down in hairs shed. When I tried RU my shedding slowed down drastically by the 6th to the 7th week to almost no hairs shed on a single day. Unfortunately for me I never saw results of growth at 4 months so I stopped when I ran out of Ru.

 

[Dr sanches]

Maybe because hair growth doesn’t happen until a few months in. Hair loss reduction happens a lot sooner but I don’t think they report that. I do believe products work immediately but you just don’t see results right away. In a letter of weeks some see big sheds while others see a slowing down in hairs shed. When I tried RU my shedding slowed down drastically by the 6th to the 7th week to almost no hairs shed on a single day. Unfortunately for me I never saw results of growth at 4 months so I stopped when I ran out of Ru.

You know pyri is a scam because it supposedly has a 4 times higher binding affinity than ru . But in our group buys people are seeing results on ru but not pyri

 

[bridge945]

You know pyri is a scam because it supposedly has a 4 times higher binding affinity than ru . But in our group buys people are seeing results on ru but not pyri

Bro I’m on the front line mixing this sh*t everyday for years. I’m not saying in 2 days I grow hair back, after a couple days on ru you can feel it, shedding down, less hair on my brush and the tightness gone in my scalp.

i don’t care if you believe me or not but naming dropping…..retards???? This is a forum to discuss all subjects around hair loss from different people all over the world and you just displayed what kind of person you are.

Not true on the first account, and most ru users don’t report much maintenance at best, and there is rarely an images showing before and afters.
Where are these people coming from, if we treated finasteride like you treat ru everyone from 1999 to now, with hair loss, would be bald.

 

[jjoshh8]

Not true on the first account, and most ru users don’t report much maintenance at best, and there is rarely an images showing before and afters.
Where are these people coming from, if we treated finasteride like you treat ru everyone from 1999 to now, with hair loss, would be bald.

dose accounts for a lot. If you don’t have results maybe the dose isn’t high enough. As far as pictures, you really think you can trust any pictures? I wouldn’t waste my time to post them, dudes like ragnar just reply with their crap. People can switch them around, post a pic of today and another one of 2 years ago and say look at my amazing results.

 

[Dr sanches]

dose accounts for a lot. If you don’t have results maybe the dose isn’t high enough. As far as pictures, you really think you can trust any pictures? I wouldn’t waste my time to post them, dudes like ragnar just reply with their crap. People can switch them around, post a pic of today and another one of 2 years ago and say look at my amazing results.

Ask people in pyri group buys they aren’t see sh*t and if that Leak was true about 24 weeks showing dutasteride results then we should see some results kintor is scam I’ve been saying it it’s literally topical olive oil

 

[RagnarLothbrok]

Focusing on what people here call "shedding" is not a good metric for treatment response. Minoxidil in fact has one of the most severe shedding responses. finasteride/dutasteride doesn't have a strong shedding response but sometimes it can increase or reduce. Both drugs work for hair loss and you can see there's literally 0 correlation to "shedding after taking the drug" making it more effective. Some drugs might induce shedding short-term and others wouldn't and this shouldn't mean anything. All these nonsense keeps confusing people. No wonder the pyri group buy is full of paranoid nocebo echo chamber.

The only way to know if a hair loss drug works or not is measuring hair count after 6 months and thats why clinical trials work that way. If shedding was ever a good metric, it would have been included as a parameter in trials but guess what... it's never relevant in any trial.

 

[RoryGall29]

Focusing on what people here call "shedding" is not a good metric for treatment response. Minoxidil in fact has one of the most severe shedding responses. finasteride/dutasteride doesn't have a strong shedding response but sometimes it can increase or reduce. Both drugs work for hair loss and you can see there's literally 0 correlation to "shedding after taking the drug" making it more effective. Some drugs might induce shedding short-term and others wouldn't and this shouldn't mean anything. All these nonsense keeps confusing people. No wonder the pyri group buy is full of paranoid nocebo echo chamber.

The only way to know if a hair loss drug works or not is measuring hair count after 6 months and thats why clinical trials work that way. If shedding was ever a good metric, it would have been included as a parameter in trials but guess what... it's never relevant in any trial.

I think also that many users here are expecting from the drug massive regrowth, while the main objective is maintenance.

 

[Dr sanches]

Focusing on what people here call "shedding" is not a good metric for treatment response. Minoxidil in fact has one of the most severe shedding responses. finasteride/dutasteride doesn't have a strong shedding response but sometimes it can increase or reduce. Both drugs work for hair loss and you can see there's literally 0 correlation to "shedding after taking the drug" making it more effective. Some drugs might induce shedding short-term and others wouldn't and this shouldn't mean anything. All these nonsense keeps confusing people. No wonder the pyri group buy is full of paranoid nocebo echo chamber.

The only way to know if a hair loss drug works or not is measuring hair count after 6 months and thats why clinical trials work that way. If shedding was ever a good metric, it would have been included as a parameter in trials but guess what... it's never relevant in any trial.

You retard I’m in 2 group buys and nobody is even seeing maintence even on month 4.

 

[losingbattle88]

That is exactly how it works. I’ve been on ru for a few years and 100% works like that

It caused more shed for me. Its placebo for you.

 

[pegasus2]

There's opposite ends of the spectrum. There's people who give up after 2 months and move onto the next cope, and then there's people who try one thing at a time so by the time they find something that works they are too old for it to matter. It's near impossible to cure a polygenic disorder with any single drug. What we are looking for is the right cocktail of drugs. If the cocktail is right then it shouldn't take more than 3 months to see new hairs. If you're only on a single treatment then you can't expect anything to work that well so you need at least 6 months to know if it's working.

 

[Dr sanches]

There's opposite ends of the spectrum. There's people who give up after 2 months and move onto the next cope, and then there's people who try one thing at a time so by the time they find something that works they are too old for it to matter. It's near impossible to cure a polygenic disorder with any single drug. What we are looking for is the right cocktail of drugs. If the cocktail is right then it shouldn't take more than 3 months to see new hairs. If you're only on a single treatment then you can't expect anything to work that well so you need at least 6 months to know if it's working.

Cope if you don’t see Finasteride results in 6 months the drug isn’t working for you

 

[RagnarLothbrok]

most hair loss treatments only have 1/3 of the sample size have noticeable hair growth in trials, the other 2/3 slightly improves or mantains

you are basing everything off a ridiculously small sample size of people... not too useful

 

[jjoshh8]

Focusing on what people here call "shedding" is not a good metric for treatment response. Minoxidil in fact has one of the most severe shedding responses. finasteride/dutasteride doesn't have a strong shedding response but sometimes it can increase or reduce. Both drugs work for hair loss and you can see there's literally 0 correlation to "shedding after taking the drug" making it more effective. Some drugs might induce shedding short-term and others wouldn't and this shouldn't mean anything. All these nonsense keeps confusing people. No wonder the pyri group buy is full of paranoid nocebo echo chamber.

The only way to know if a hair loss drug works or not is measuring hair count after 6 months and thats why clinical trials work that way. If shedding was ever a good metric, it would have been included as a parameter in trials but guess what... it's never relevant in any trial.

????
The way to know if a hair loss drug works is if it stops hair loss

 

[jjoshh8]

It caused more shed for me. Its placebo for you.

That makes 0 sense …Placebo? More then 3 years come on man. I should be bald, pretty good placebo

 

[corkmeister]

????
The way to know if a hair loss drug works is if it stops hair loss

He's right though, shedding is not a good metric and a lot of people place way too much weight on it (I'm guilty of it myself). The problem is that a lot of people believe that hair loss literally equals the amount of hairs you lose, when it much more has to do with the way in which those hairs grow back. This is why you get people claiming they're only losing 2 hairs per day after starting treatment, it's just self-delusion on display

It's not a useless metric though, I believe there's some correlation of relationship with treatments and I believe the original Mazzarella study on topical finasteride used a variation of shedding (the shower test) to prove results but in the context of these groupbuys it's a disaster, people are way too neurotic and it just obscures any results or lack of it. Day2: SHEDDING IS DEFINITELY DOWN!! DAY15: SHEDDING HAS INCREASED!!!

 

[Redgate]

"shedding" is a metric usually given by obsessed people who check their hair every few hours, compulsively rub it to see "hair sheds", count the number in the drain, the hair brush, the floor, the pillow, the sink etc. if you don't take before & after pics you're lying to everyone including yourself.

 

[jjoshh8]

He's right though, shedding is not a good metric and a lot of people place way too much weight on it (I'm guilty of it myself). The problem is that a lot of people believe that hair loss literally equals the amount of hairs you lose, when it much more has to do with the way in which those hairs grow back. This is why you get people claiming they're only losing 2 hairs per day after starting treatment, it's just self-delusion on display

It's not a useless metric though, I believe there's some correlation of relationship with treatments and I believe the original Mazzarella study on topical finasteride used a variation of shedding (the shower test) to prove results but in the context of these groupbuys it's a disaster, people are way too neurotic and it just obscures any results or lack of it. Day2: SHEDDING IS DEFINITELY DOWN!! DAY15: SHEDDING HAS INCREASED!!!

I said if it stops hairloss never said shedding. If my hairline keeps going back then it’s not working

 

[losingbattle88]

I said if it stops hairloss never said shedding. If my hairline keeps going back then it’s not working

I lost like 4 to 5 hairs in shower after using dutasteride for 1.5 years. What Happaned in the end? I lost like 30% of my hair density. Shedding means squat. Tbh more hairfall means your hair is growing because it reached its hair cycle. If you dont shed at all it means your hair isnt growing. Which isnt Good.

 

[losingbattle88]

Fgsfds fuk you.