- Reaction score
- 1,400
I’ve seen this in the patent too, and I think it has to been a typo or something. Pge1 definitely does not have an effect on alpha reductase. I’ve tried to find information on pge1 inhibiting alpha reductase and it just doesn’t exist. It doesn’t make sense that prostaglandins would have any affect on hormones, because it is the opposite - hormones influence prostaglandin release in the body and not the other way around. I think this sentence may be talking about equol in the lotion, which also does not inhibit alpha reductase. Instead, it attaches itself to DHT preventing the hormone from binding to its androgen receptor where applies (in this case, the scalp). If I’m incorrect about any of the information please show me evidence otherwise so we can all have a better understanding of it.From the Brotzu patent:
https://patents.google.com/patent/EP3145490A1/en
"PGE1 is a drug acting on several levels: it inhibits type 1 and 2 alpha- reductase, is a vasodilator and improves angiogenesis."
Is this really the case? I've never heard this mentioned before..