If you mean TRT, then I dont think it would affect them visibly, a lot of people doing TRT dont lose more hair on it afaik. Depends how much you give them. I dont think they suffer acne really.It would be interesting to see what the hair loss effects of T supplementation on Native American hair might be. Perhaps it's a threshold issue and at some levels effects would be noticed. I assume they don't suffer from acne among N.I.'s either.