Thanks for your interest and the links. What i suggest is that there are two things going on when it comes to hair growth. There is the normal hair cycle, and the mechanism of contact inhibition. I dont think that the hair cycle in itself is the problem in male pattern baldness, i think the anagen phase is switched off early by external pressure, then this modifies the other phases of the cycle. I think if you change the external pressure, the hair cycle can sort itself out. My concern with the hair multiplication and cell/genetic manipulation experiments, is that these are not going to get around normal contact inhibition, if this is the problem in male pattern baldness. No one knows much about the pathways involved in contact inhibition, only that this is a basic reaction to cell division and tissue growth in-vivo. This prevents tissue growth from invading the space of other tissues, and all normal cells react to contact inhibition of growth. The central characteristics of cancer cells is they lose this reaction, and this is how they cause damage to healthy tissues. We do know that the Wnt's pathway, b-catenin, and TGF beta-1 are linked to the contact inhibition process, and these factors have been suggested as relevant in male pattern baldness. Fuchs did a mouse study where she manipulated Wnt's and b-catenin, and grew significant amounts of hair. The problem was the tumor developement that went with it. http://www.hhmi.org/fuchs/index.html In my opinion, there could be ways that HM could work, a wounding process should help because it is thought that contact inhibition is "relaxed" because of injury to allow better healing. Some proposed procedures claim a matrix of some kind to help in tissue growth, basicaly a "mould" that allows tissue growth. I think there could be easier ways forward with research shifted to the surrounding tissue, and maybe this currect HM research will reach that conclusion?