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f*** Allergan. Serial Dropping Of Future Treatments.

Discussion in 'New Research, Studies, and Technologies' started by jamesbooker1975, Nov 17, 2018.

  1. jamesbooker1975

    jamesbooker1975 Senior Member My Regimen

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    First they drop BItamoprost , even after the positive results on phase 2. Now, Setipiprant is not longer on their pipeline and they never release the results of phase 2 ( even when one their site they tell they make the results public )
     
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  2. PeggyPeterson

    PeggyPeterson Established Member My Regimen

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    Drug companies a profit driven. So if Allergan did really drop Setipiprant, it was possibly because the drug wasn’t as effective and it safer than current treatment options.

    @westonci did seem to show results though. Maybe that was mostly from dermarolling and PGE2
     
  3. jamesbooker1975

    jamesbooker1975 Senior Member My Regimen

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    Well, not. First at all they drop Bitamoprost, that was show really good results. Problem is , it look like they want the magic bullet. They don't care the " same results than finasteride but without side effects " .
    Thruth is, that a 2 gram dose per day for Androgenetic Alopecia, is not something that you can easily sell ( 4 pills per day ) , is like the antimarketing. But, should be nice, if they release the results of the phase 2 , like, for example, Glaxo did with Dutasteride.
     
  4. alibaba92

    alibaba92 Senior Member My Regimen

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    1) I thought we should be waiting for fevi instead ?

    2) They will publish data in March 2019, exactly 1 year after trial end. I remember a member here emailed and got reply from Allergan

    3) I am no surprise that seti will fail to enter the market since there is no regrowth.
     
  5. BalderBaldyBald

    BalderBaldyBald Experienced Member My Regimen

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    Bitamoprost had some nasty sides, including their magical eyelash grower.
    As for Setipiprant, of course they dropped it, this does not work on Androgenetic Alopecia

    Another day, another treatment failling. That's why trials are for.
     
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  6. jared garnith

    jared garnith Established Member My Regimen

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    I mean even if seti did come through I feel like it would've came around the same time as cb0301 and I feel cb would be more effective and have fewer side effects, but the thought of adding seti onto an antiandrogen for people who have aggressive loss does make this unfortunate
     
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  7. TK421

    TK421 Experienced Member My Regimen

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    Tried oral seti which I bought from Lyphar and didn't have any noticeable results in hair growth or reduction in shedding. It's possible the results of their study didn't produce the results they were hoping for either.
     
  8. kiwi666

    kiwi666 Experienced Member My Regimen

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    This
     
  9. PeggyPeterson

    PeggyPeterson Established Member My Regimen

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    If Novartis thought fevipiprant would work for Androgenetic Alopecia, wouldnt they patent it and do some proof of concept trial by now.
     
  10. PeggyPeterson

    PeggyPeterson Established Member My Regimen

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    Unfortunately CB isn’t a sure thing yet. The best litmus test is to see if Winlevi gets marketed in 2020. Even successful phase 3 trials get knocked back by FDA.. cautiously optimistic about this one.
     
  11. Sanchez1234

    Sanchez1234 Experienced Member

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    From what i hear fevipiprant to setipiprant is like dutasteride to saw palmetto. Plus fevi can be used as a topical and builds up. Seti is sh*t
     
  12. jared garnith

    jared garnith Established Member My Regimen

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    Yeah just the problem with fevi is that I doubt many doctors would be willing to prescribe it off brand
     
  13. jamesbooker1975

    jamesbooker1975 Senior Member My Regimen

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    1) Please put some prove , some study showing of this nasty side effects
    2) MOst propably, you are wrong. First at all, the 2012 study was outstanding , simple perfect. It shows that high PDG2 inhibit Hair growth exactly as it happen with male pattern baldness, it show that male pattern baldness have high PDG2 and it even show that blocking the receptor , the hair grew again .
    And, by last, The cetirizine study made public this year, also show that it works for male pattern baldness . But , we will not for sure if they release the results or when fevipiprant became commercially available for Asthma .
     
  14. jamesbooker1975

    jamesbooker1975 Senior Member My Regimen

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    Sorry, but home made drugs that y
    Actually , not . It depend on many other things. For example, Merck never tested Finasteride for acne, but it is give is as alternative treatment to treat acne. Also, neither did it for hirsutism in women , same thing .
     
  15. Badbald

    Badbald Established Member

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    How recently did they take it off their timeline?
     
  16. PeggyPeterson

    PeggyPeterson Established Member My Regimen

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    I didn’t see it there when I checked 3-4 months ago. I asked people on the seti thread but my post didn’t get response.

    Did they have it there in the first place? Someone mentioned that they only put things up that are going to be released within 2 years
     
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  17. SamFT

    SamFT Established Member My Regimen

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    If you look at allergans pipeline they actually took off over half of their treatments. They only have treatments that will be available in the next year or two now. I don’t think they actually dropped setipiprant
     
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  18. Badbald

    Badbald Established Member

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    Thats good to know, sort of counting on this
     
  19. HairSuit

    HairSuit Established Member My Regimen

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    I sure hope, because after 9mos on seti (or what I think is seti) I’m not encouraged
     
  20. alibaba92

    alibaba92 Senior Member My Regimen

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    @jamesbooker1975 seriously ?
     

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