Westonci appeared to have some improvement with seti but nothing too dramatic, he wasn't using a 5ar inhibitor though. Swiss was using dutasteride with the prostaglandin protocol, which according to the theory androgens increase pgd2, so it makes sense that if you don't use a 5ar inhibitor, you would need a high enough dose to "outrun" the pgd2 production from androgens.
There are many who use finasteride and minoxidil and get results for a couple years but eventually lose ground again, I believe this is also what happened to Swiss, his last photo he posted in my opinion looked worse than the previous photo and he hasn't updated his blog in years, he also claimed to be close to his juvenile hairline but after never showed pics from enough distance to show it.
The only evidence for the prostaglandin method I've seen so far is from Swiss and Westconli but that doesn't satisfying prove it would cause long term healthy anagen hair growth.. Minoxidil if used alone also regrows hair, sometimes for months or years but it's well known that if you don't take drugs to alter your hormones, then genetics eventually catch up again.. So, how can we know that the same thing doesn't happen with the PGD2 theory?
Swiss even often recommended not using Keto shampoo because keto reduces Pge2. Lol
Swooping had some interesting viewpoints throughout this thread --->
https://www.baldtruthtaIk.com/threads/19018-Setipiprant/page11
I agree Hair is a multi angled approach.and
maybe pdg2 inhibitors/ pge2 could be a
part of a non-feminizing solution someday. but alone it is not the cure. PGD2 is not the only thing bad for hair an PGE2 is not the only thing good for hair. I doubt its the sole reason for balding. theres other negative growth factors too, Tgfb, dkk-1, oxidative stress, IFN-gamma, etc.
