Exploring The Hormonal Route. Hair=life.

[Yar]

View attachment 129006

normal male range estradiol is <50pg/ml... estradiol valerate 2mg/d will increase it up to 60... not so much difference

each has its own level

 

[I'mme]

I'm 21 yo and I was on 50 mg CPA for about 2,5 months and I'm still losing hair.
My chest hair are almost gone, my skin is the best in my entire life, dick works good, i've become more emotional and I'm still losing ground.

I've been on check-up and my T is 14 (8-30 is normal) and liver is all good.

It's hard to say for me but probably nothing will save me. I'm gradually losing all hope and motivation.

I'm going to increase CPA dosage to 75 -> then check-up -> then add estradiol, but I don't believe that ANYTHING will save my hair anymore.

Oh, and you forgot to mention that you've been a lurker here since long but just created account. Never mind

 

[Yar]

[QUOTE = "ali.talebi1994, post: 1838028, member: 143339"] отсутствие либидо не означает бесплодие ... либидо вернется после отмены препарата, но если вы увидите, что размер ваших яичек значительно уменьшается это не хороший знак ...
но я не думаю, что один эстрадиол в дозе 2 мг / сутки будет оказывать неблагоприятное воздействие на яички ...
и еще одна вещь: Cypro, как говорят, оказывает вредное воздействие на печень, но валерат эстрадиола не так вреден для печени, как Cypro ... Кроме того, эстрадиол является более мощным, чем Cypro, с точки зрения антигонадотропных эффектов, так что если вы принимаете эстрадиол Вы бы лучше не использовать Cypro [/ QUOTE]
мои яйца не имеют значения для меня

 

[keepcoolmybabies]

Sure, but there is a price to pay. Spironolactone fucked my face.

how so?

 

[ali.talebi1994]

if you have androgenetic alopecia, then this will not help you. It can be used in pre hrt for 1 month

yeah im suffering from androgenic alopecia... i tried finasteride 1mg/d last year for 8 months but i didnt see noticeable changes, and also it caused more sebum production on my scalp...
i have recently started Rogaine (2 times a day) + microneedling 1x/w (it has been about one month)... it seems that its working
and im thinking about adding 2mg/d estradiol valerate to my regimen

 

[Yar]

yeah im suffering from androgenic alopecia... i tried finasteride 1mg/d last year for 8 months but i didnt see noticeable changes, and also it caused more sebum production on my scalp...
i have recently started Rogaine (2 times a day) + microneedling 1x/w (it has been about one month)... it seems that its working
and im thinking about adding 2mg/d estradiol valerate to my regimen

then cancel all that you accepted earlier.

 

[Father_of_Shiseido]

huh? in what way? what happened?

@keepcoolmybabies ;
My lower jaws and chick are thinning a lot. It looks like a women’s face. My body is melting. One can spot a difference.

 

[ali.talebi1994]

[QUOTE = "ali.talebi1994, post: 1838028, member: 143339"] отсутствие либидо не означает бесплодие ... либидо вернется после отмены препарата, но если вы увидите, что размер ваших яичек значительно уменьшается это не хороший знак ...
но я не думаю, что один эстрадиол в дозе 2 мг / сутки будет оказывать неблагоприятное воздействие на яички ...
и еще одна вещь: Cypro, как говорят, оказывает вредное воздействие на печень, но валерат эстрадиола не так вреден для печени, как Cypro ... Кроме того, эстрадиол является более мощным, чем Cypro, с точки зрения антигонадотропных эффектов, так что если вы принимаете эстрадиол Вы бы лучше не использовать Cypro [/ QUOTE]
мои яйца не имеют значения для меня

thanks to google translate ...
then you are free to go

 

[Yar]

thanks to google translate ...
then you are free to go

I am from Russia. How can I still communicate with you?

 

[Father_of_Shiseido]

@I’mme ; how are you doing on spirinolactone?

 

[DinkyDino]

most people here block DHT, it doesn't stop their hairloss.

then they either go on the spironolactone/estrogen route, the cpa route, or the bica/raloxifene route. then they complain why they are still balding..

first of all spironolactone is an INSANELY weak anti androgen. 1mg of Spironolactone only blocks 0.6375ng/dl of total testosterone and it has partial agonist activity.

cyproterone doesn't reduce T that much but a lot more than spironolactone. Cyproterone by itself lowers T by around 40-70% and weakly inhibits the AR with partial agonist activity (albeit a lot stronger than spironolactone).

and then with bicalutamide. yeah this is the strongest route but I swear 90% of the people I see on bicalutamide on reddit are on letrozole/taamoxifen/raloxifene/arimidex all at the same time and at high doses. Most of the medical literature supports the theory that Bicalutamide blocks 8x more Total testosterone than spironolactone if not more. And with silent antagonist activity.

I don't like to admit it but that is a pattern I have been seeing. Most people with success including the OP of this thread initially started on Cypro and then moved to bica. I can see why people are apprehensive though. Cypro and bica at the same time is a tall order for people worried about their health. Cypro in particular is risky though I see you're taking a low dose. That's why some just opt for Bica + e withdut but even I'm not sure how effective that is. Some say to start on cypro and then quit it because the damage it does to your balls are permanent but that might allow you to move on to bica. I guess it comes down to how far you are willing to go for a maybe since nothing is guaranteed.

 

[ali.talebi1994]

most people here block DHT, it doesn't stop their hairloss.

then they either go on the spironolactone/estrogen route, the cpa route, or the bica/raloxifene route. then they complain why they are still balding..

first of all spironolactone is an INSANELY weak anti androgen. 1mg of Spironolactone only blocks 0.6375ng/dl of total testosterone and it has partial agonist activity.

cyproterone doesn't reduce T that much but a lot more than spironolactone. Cyproterone by itself lowers T by around 40-70% and weakly inhibits the AR with partial agonist activity (albeit a lot stronger than spironolactone).

and then with bicalutamide. yeah this is the strongest route but I swear 90% of the people I see on bicalutamide on reddit are on letrozole/taamoxifen/raloxifene/arimidex all at the same time and at high doses. Most of the medical literature supports the theory that Bicalutamide blocks 8x more Total testosterone than spironolactone if not more. And with silent antagonist activity.

on of the most important issues in using any of these antiandrogen drugs, is that you should take care of your liver and regularly check your liver enzymes...
i was on spironolactone 200mg/d for 3 months... not only it didnt work but also it increased my liver enzymes by 4-5 fold... when i saw the blood test results i took it to a specialist doctor and he recommended me to stop the drug immediately... so i stopped the spironolactone and after 3 month of discontinuation i did another blood test and my liver enzymes were in normal range

 

[Ikarus]

on of the most important issues in using any of these antiandrogen drugs, is that you should take care of your liver and regularly check your liver enzymes...
i was on spironolactone 200mg/d for 3 months... not only it didnt work but also it increased my liver enzymes by 4-5 fold... when i saw the blood test results i took it to a specialist doctor and he recommended me to stop the drug immediately

Spironolactone raised your liver enzymes? That’s weird, I thought spironolactone was used for cirrhosis of the liver... And, I agree. I think everyone should be getting frequent blood tests, at least once every three to six months.

 

[keepcoolmybabies]

I don't like to admit it but that is a pattern I have been seeing. Most people with success including the OP of this thread initially started on Cypro and then moved to bica. I can see why people are apprehensive though. Cypro and bica at the same time is a tall order for people worried about their health. Cypro in particular is risky though I see you're taking a low dose. That's why some just opt for Bica + e withdut but even I'm not sure how effective that is. Some say to start on cypro and then quit it because the damage it does to your balls are permanent but that might allow you to move on to bica. I guess it comes down to how far you are willing to go for a maybe since nothing is guaranteed.

OP moved to bica because he believes it's ultimately a stronger regimen. But CPA didn't lose effectiveness for him prior to switching.

 

[Father_of_Shiseido]

if ur taking that much estrogen u wouldn't benefit from anything more than 12.5mg of Bicalutamide. my regimen is nowhere near excessive

and I took cpa between 50-75mg by itself before and it didn't even slightly slow my hairloss down. the only thing that has worked is bicalutamide in far superiority to everything else I've tried
.View attachment 129008
also another update: I waxed my forehead hairs I got from bica and this is what my hairline looks like at the moment. (thanks for the suggestion @I'mme )

I think your face begin to feminize. What do you say?

 

[Yar]

why would u even take spironolactone lmao. its literally weak as heck and has more side effects than oral minoxidil.

You would need roughly 1500-1600mg of spironolactone to fully block male levels of testosterone and even then partial agonist activity would derail the complete ar signaling shutdown.

are you advising such doses in your mind? right now somebody will listen to you and start taking such doses! don’t know don’t advise! I talk with MTF, their modes are safe from the point of view of health and hair. I and MTF myself

 

[Father_of_Shiseido]

ill send u a selfie rn, I don't think my face changed at all in my honest opinion.

Send me your selfie, I will send you mine.

 

[Ikarus]

are you advising such doses in your mind? right now somebody will listen to you and start taking such doses! don’t know don’t advise! I talk with MTF, their modes are safe from the point of view of health and hair. I and MTF myself

ugh invented knowledge

 

[ali.talebi1994]

I am from Russia. How can I still communicate with you?

no matter, we can use google translate
i meant that you are free to use anti androgens if your balls are not a matter for you but be careful of your liver

 

[Yar]

spironolactone also causes high blood pressure, potassium deficiency, edema, kidney disease, liver scarring, and severe heart liver. it should be removed as an anti androgen.

spironolactone saves potassium