if my dht lowered to 22 ng dl after 1 year of dutasteride and then after starting hrt down to 5,0 ng dl am i excluded ?
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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I still don't trust that theory. They are saying the culprit is DHEA and DHEA-S yet when my DHEA and DHEA-S were higher back in 2023 my DHT was 4.5-5 ng/dl and now my DHEA and DHEA-S are lower and my DHT sits on 18 to 22 ng/dl. I won't say the theory is fake by any means, some peope could fit on that theory but it is not true for me.
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I am gonna start prog again and this time Im gonna keep taking it cause i have nothing to lose.
In this study '' https://pubmed.ncbi.nlm.nih.gov/25201454/ '' they mention this:
I will not be using abiraterone for obvious reasons but maybe e2 + bica + dutasteride kinda leads to a similar blockade of androgens in non high DHEA/DHEA-S people, so maybe prog could decrease dht in presence of dutasteride + e2 + bica in people without heightened DHEA and DHEA-S (again I am speculating and I will test it since I have nothing to lose at this point).
I am starting with 100 mg prog rectally and will increase it if I don't feel anything is improving or if my next blood test shows similar DHT as now. If my DHT gets lower I will keep the 100 mg and if it gets higher I will stop it entirely.
In this study '' https://pubmed.ncbi.nlm.nih.gov/25201454/ '' they mention this:
I will not be using abiraterone for obvious reasons but maybe e2 + bica + dutasteride kinda leads to a similar blockade of androgens in non high DHEA/DHEA-S people, so maybe prog could decrease dht in presence of dutasteride + e2 + bica in people without heightened DHEA and DHEA-S (again I am speculating and I will test it since I have nothing to lose at this point).
I am starting with 100 mg prog rectally and will increase it if I don't feel anything is improving or if my next blood test shows similar DHT as now. If my DHT gets lower I will keep the 100 mg and if it gets higher I will stop it entirely.
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your free T level is higher as well, probably corresponding to the increase in DHT seen
And your SHBG is very high. It is soaking up all the E that you have in your body, leaving you with more fractional free T
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It is not higher than when i had very low DHT tho(in july 2023 i had 3 pg/ml T yet the lowest DHT i ever had), so it still makes no sense. SHBG is not that high, only in august 2024. SHBG actually helps because it binds way more to T and DHT than e2 so it is doing its function there acting as an AA
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Yet it makes no sense how DHT shot to the double digits. And also, SHBG does prefer binding to T and DHT more, but when androgen levels are already castrate range / low levels, it starts soaking up Estradiol instead. Since you have high E levels, high SHBG is doing more harm in this case
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Yeah I think i am an exception cause i dont have high DHEA-S/DHEA/Androstenedione, I also take dutasteride so it makes things even weirder. As I said I don't have many new stuff to use anymore so I will try with progesterone and see what I can achieve
Yeah im planning on lowering it when I get my dht under control and get physically castratred which should happen at any point cause as i said previously my testicles are ischemic and it is a matter of time since they become necrotic and start to give me serious issues. I remember when I had lower shbg I had more feminization but I always blame on dht and not shbg but prob both are contributing.
When high e2 levels can spike shbg and so doing problems? Over 1000 pg ml?
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Yes
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If you found the cause make sure to tell us. This sh*t is so criminally understudied it's crazy
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I will. I rly hope progesterone can save me cause if it doesnt, it's over for me
if my e2 levels were 429 pgml after 14 days my prevoius injections is there a chance that they might have been higher on the 7th day or l 2-3 days after the first one? The simulator is not trustworthy to be honest or maybe im just a dickhead and cant use it
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What's the reason you're adding prog ?
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Try to see if it fixes my metabolism. It is so fucked rn maybe it helps with dht or maybe not who knows