Dr Tsuji And Hairloss Treatment Questions

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The biggest issue with hair transplants is not having enough donor hair. You only need about 50% of your original density to not seem like you’re balding. But 50 % is hard to achieve on high Norwood’s. Most individuals do not have the donor supply for that. I always felt that hair transplants are best for Nw3 and lower. Rarely do I see a Norwood 6/7 whose hair transplant looks good. Most of the time it is just a comb over and the doctors use those angles to make it look better. Btw when you see before and after pictures the lightning will always be different. Anytime my doctors took before and after they changed the lightning to make it look worse prior to surgery. If replicel or some type of growth stimulant comes out, a combination of hair transplant and growth stimulant would solve a lot of people’s problem. It would be a bridge until Tsuji solves the problem.

Personally my plan is to Fue most of my hair transplants out once Tsuji works. Basically an inch of the hairline, this is where all the grafts were placed. But I had so much hair, many of the grafts did not work and I just had major shock loss. So I don’t have many grafts to punch out.

Depending on the advancement in skin grafting, I thought about doing a hair line excision and then planting new skin over the excision. If we are able to print new skin, in my opinion, this would be the best option. It would be a lot faster, get more grafts out, and you would have new skin ready for Tsuji grafts to be planted. It would be something I consider doing to my whole head and so I could be done with hair loss forever. I figure to share my plan for anyone who feels they are stuck with their hair transplants, in the future there will be options for all of us.

Here are some interested things they are doing with skin. There are many more than just these companies.

https://3dprint.com/211365/3d-printed-electronics-cells/

“it can also be used to 3D print cells directly onto wounds. McAlpine and his team partnered with University of Minnesota Department of Pediatrics doctor and medical school Dean Jakub Tolar, an expert on treating rare skin diseases. The team successfully used the 3D printer and a bio-ink to print cells directly on the skin wound of a mouse. This could lead to advanced treatments for patients with skin diseases or injuries like burns.”

https://www.livescience.com/62511-skin-printer-heal-deep-wounds.html

“A new device that resembles a glue gun is 3D printing skin, and researchers hope that it can one day be used to heal very deep wounds.”…..”

“This complicated network of cells, blood vessels, nerves and hairs serves to protect us from the world of germs we live in. But some kinds of wounds — such as burns — can wipe out all three layers of skin, creating portals into our body for thirsty pathogens.

“The printed skin that the researchers tested didn't replicate all of these elements, however. Rather, the device deposited only certain cells, including keratinocytes and fibroblasts — but the scientists hope that one day it will be able to leave behind the "perfect skin," complete with stem cells that can grow into hair follicles, blood vessels and various types of cells in the correct configuration, Amini Nik said.

This isn't the first "skin-printing" device out there. For example, a group of Spanish researchers created such a device in 2016. But it is the first device that could potentially allow doctors to immediately deposit skin onto a wound without going through a lab or other donors first: Doctors could potentially take stem cells from the patient (for example, from fat tissue or bone marrow) and feed them into the device at the time of the procedure, Amini Nik told Live Science.”

You also have poietis, the team working with loreal, making progress. Taking from their website….

“The launch of a Bio-impression-produced fabric, the Poieskin ® Human Total Skin Model manufactured by Laser Assisted Bio-Printing, is a first and marks a breakthrough in the emergence of Bio-Printing technologies and tissue engineering …..Pessac, France, January 23, 2018 - Poietis, a leading provider of 4D Bio-Printing solutions, today announced the commercial launch of Poieskin ®, its first bio-printed human skin model.”

“Poietis, a specialist in bio-printing, announces that it has completed a € 5 million series A round of financing to fund technological developments that would allow the first implantations of bio-printed tissue in a patient as early as 2021.”

Poietis is also working on printing follicles and has support from L’oreal and BASF. They started with 25 scientist now have over 50. I believe they are someone to keep an eye out for if Tsuji does not start trials next year.



Also we are able to print Human pluripotent stem cells......

https://www.technologynetworks.com/cell-science/news/human-pluripotent-stem-cells-successfully-3d-printed-290630

“A team of researchers at the University of Wollongong-headquartered ARC Centre of Excellence for Electromaterials Science (ACES) have discovered a way to print human induced pluripotent stem cells (iPSCs) using a custom developed bioink…..The team has already begun preclinical safety studies with the aim of advancing tissues further for use in medical research, regenerative medicine and personalised medicine.”

and we know what those cells can do for hair loss.

We are advancing faster in medicine each year. 5 years ago they use to struggle to get cells to survive the printing process, now they can print them onto people’s hands. In 2006 was the first time they learned about reprogramming ips cells. 12 years later we can now print them. Which is crazy when you think about it, since it took from the 1950s when they started question if differentiated cells still had the ability to be pluripotent, until 2006 for another major breakthrough. Now we had many more breakthroughs since 2006 with ips cells. And don’t always knock mouse studies, the 2006 ips study came from a mouse model. Now they are conducting the first heart treatment with ips cells in Japan this year. All of these advancements and use of stem cells will just help a cure come to the market faster. If we can ensure the safety of stem cells and other printing organs, doubt clinical trials will take 10 years in the US.

I don’t know when it will be solved, but I do not believe it will be 15- 20 years. I believe we are in that 5 year range where we will see it solved. And 1 to 3 years for something significantly better than the options we have now to help with hair loss.


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But for real, I agree
 

Mykonas

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I don’t know when it will be solved, but I do not believe it will be 15- 20 years. I believe we are in that 5 year range where we will see it solved. And 1 to 3 years for something significantly better than the options we have now to help with hair loss.

Read your post great analysis, i agree with you although the fact that we came far doesn't necessarly mean that we're close, tsuji is today the only one that's tackeling hairloss through cells 3d printing once he shows the world that he made it (which he partially did with his papers and it's strange that no other big corp launched their own research on this) it will certainly draw more attention to this approach which will make things go ten times faster than today.
Personnaly i'm not interested when a cure is out, i'm only intersted when i'll be able to get my hair and i know through facts not assumptions that it wont be the case before 10 years minimum due to many reasons : logistics, price... among my bigest concerne that is other issues with this technology will pop up once they start testing on humans which 100% will be the case
 

rmzn

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When the treatment of tsuji occurs in 2020 or 2021, when will we have it. what the price will be. I will be very happy if you inform me
 

Marcaronii

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When the treatment of tsuji occurs in 2020 or 2021, when will we have it. what the price will be. I will be very happy if you inform me
The treatment will come in 3020 and it will cost USD1,000,000. Nobody knows you dumbf***. Stop asking stupid questions.
 

lemoncloak

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The average density varies between 60 to 120 follicles per cm2. They will definitely obtain 70 or 80. Which I wouldn't mind tbh
Check this out. http://www.keratin.com/aa/aa014.shtml
Average density for white nw1 men is about 250 hairs (not follicles) per cm. Ronaldo could be over 300. Tsuji has shown 120 so far while transplants remain at 60-70.
120 is a decent result but it's what you'd describe as thin hair, think east asian people.
I don't think the Tsuji team was trying to maximize results on that study that early on in development however.
 

Trichosan

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Check this out. http://www.keratin.com/aa/aa014.shtml
Average density for white nw1 men is about 250 hairs (not follicles) per cm. Ronaldo could be over 300. Tsuji has shown 120 so far while transplants remain at 60-70.
120 is a decent result but it's what you'd describe as thin hair, think east asian people.
I don't think the Tsuji team was trying to maximize results on that study that early on in development however.

And, if you're an older guy, you can get by with that less density. However, this is just the infant stage of this technology and there will be improvements likely in the biology and technique that could take packing to natural hair levels or beyond. Meanwhile, all we can do is wait.
 

Hate da Bt

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Check this out. http://www.keratin.com/aa/aa014.shtml
Average density for white nw1 men is about 250 hairs (not follicles) per cm. Ronaldo could be over 300. Tsuji has shown 120 so far while transplants remain at 60-70.
120 is a decent result but it's what you'd describe as thin hair, think east asian people.
I don't think the Tsuji team was trying to maximize results on that study that early on in development however.
Hair density is different in different scalp regions (for example, it is denser on the crown), and in different racial groups.
The density on the mouse was 129 hairs/cm², and the stem cells were most probably of a Japanese individual (East Asians sport lower hair densities on average.).
The most skilled hair transplant surgeons can achieve densities of 60-70 hair follicles/cm² (dense packing), aka similar densities to Organ Germ Technology (about half the density of nw1). Average hair transplant surgeons can achieve densities of 30-45 hair follicles/cm², or 70-100 hairs (about one third of nw1's density).
In my opinion, higher densities, close to normal, will be achieved as the technology advances. Nevertheless, in order to advance, it need be successful at lower densities, first. Unfortunately, that hasn't cropped up yet.
The first clinical trial is to commence in March 2019, aka in nine months.
In other words, we ought to wait.
 

forlorn

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Keep in mind that Organ Technologies said they can manipulate hair follicle thickness to a certain extent. I'm sure nobody here would care about having a lower density if it meant having thicker hair follicles to compensate for it.
 

mikes23

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i know through facts not assumptions that it wont be the case before 10 years minimum due to many reasons
that's an assumption in itself. If Tsuji starts the trials next year and everything goes accordingly, then we will have the cure sooner then ten years. Eventually the price will come down. I think it will be cheaper then a hair transplant due to everyone who is bald or balding will do this. Only a select people who are bald get hair transplants, so hair doctors have to charge so much. This also will be easier for hair docs to perform then hair transplants right now. All they will have to do is inject the cells. they wont have to go through the lengthy process a hair transplant requires right now. Which means they will not need as big of staff. Also, if this gets automated by something like Artas robot, it should be even cheaper. A doctor would have the robot do all the work. I believe everyone will have this procedure automated. Which leads me to my next point, do not worry about location. This will be in the states and Europe fast. Those will be the 2 biggest markets for them.

Idk what problems will occur when they test this on humans but we will see after phase 1, but I do not think their will be health problems from this, if that is what you're assuming.

the fact that we came far doesn't necessarly mean that we're close, tsuji is today the only one that's tackeling hairloss through cells 3d printing once he shows the world that he made it

Tsuji is using the organ germ method not 3d printing. Idk if that was a typo ,but 3d printing are teams like lauster and poietis. And true we may still be years away but I think we are close. Looking at it from a 3d printing standpoint. We can print blood vessels networks and dermial papilla. We can also print complex tissue now and can shape that tissue. When I see this it makes me believe we are not that far from being able to print a fully functional follicle.

but I am just speculating with what i said, lets just hope whoever solves it does it soon... we are all tired of having to deal with this.
 

Toby0823

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I'll turn 25 in 2020, and tsuji may or may not be available to the public. I'm sittin here worrying my *** off over my hairline, meanwhile my friends/guys my age are out there enjoying life and f*****g girls. Life is f*****g unfair.

You wish it’ll be available in 2020. I like how you and many others try to be optimistic by plugging “maybe 2020” then hit reality with by saying maybe not. It’s like trying to cover up your delusion.

You’ll be balding even worse in 2020 with no hope of any cures so prepare for it now.
 

Mykonas

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that's an assumption in itself. If Tsuji starts the trials next year and everything goes accordingly, then we will have the cure sooner then ten years. Eventually the price will come down. I think it will be cheaper then a hair transplant due to everyone who is bald or balding will do this. Only a select people who are bald get hair transplants, so hair doctors have to charge so much. This also will be easier for hair docs to perform then hair transplants right now. All they will have to do is inject the cells. they wont have to go through the lengthy process a hair transplant requires right now. Which means they will not need as big of staff. Also, if this gets automated by something like Artas robot, it should be even cheaper. A doctor would have the robot do all the work. I believe everyone will have this procedure automated. Which leads me to my next point, do not worry about location. This will be in the states and Europe fast. Those will be the 2 biggest markets for them.

Idk what problems will occur when they test this on humans but we will see after phase 1, but I do not think their will be health problems from this, if that is what you're assuming.



Tsuji is using the organ germ method not 3d printing. Idk if that was a typo ,but 3d printing are teams like lauster and poietis. And true we may still be years away but I think we are close. Looking at it from a 3d printing standpoint. We can print blood vessels networks and dermial papilla. We can also print complex tissue now and can shape that tissue. When I see this it makes me believe we are not that far from being able to print a fully functional follicle.

but I am just speculating with what i said, lets just hope whoever solves it does it soon... we are all tired of having to deal with this.
True but i don't agree with tsuji being easier than a hair transplant. Tsuji's process not only include implementing the follicles just like in a transplant but also culturing them which took them 8 weeks in their pilote study. that's a lengthy process
 

Marcaronii

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You wish it’ll be available in 2020. I like how you and many others try to be optimistic by plugging “maybe 2020” then hit reality with by saying maybe not. It’s like trying to cover up your delusion.

You’ll be balding even worse in 2020 with no hope of any cures so prepare for it now.
K
 
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THALL

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You balding virgin brah?

All your bros f*****g all the girls while you stand and watch, with armpit hair on your head.
lol dude I understand you are incredibly insecure about your balding, but why do you need to project your hate for yourself unto others like that? That's just childish. At least elaborate on why you think tsuji will fail
 
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