A study on pgd2 and androgens relationship

[Stating facts]

Maybe cycling Aspirin, Ceti can help maintain PGD2 levels. Using any of these long term has its own issues.

 

[MikeJay]

"It is interesting to note the opposing effects of PGD2 (the prostaglandin that induces the niacin flush) and PGE2 in the balding model (above), where chronically high PGD2 resulted in suppression of PGE2. A pulsatile release of PGD2 (an ACUTE release) as in the niacin flush would be anti-inflammatory, not pro-inflammatory as with chronically high PGD2. Hence, you could see an INCREASE in PGE2 by suppressing chronically high PGD2. The balding model, in fact, shows hair growth and the cessation of hair follicle death resulting from slight modulation in the ratio of PGD2/PGE2, in which PGE2 is increased, while chronically high PGD2 levels are reduced to “normalize” the ratio. The niacin flush causes pulsatile, not chronic, release of PGD2."

Why the Niacin Flush May Be Surprisingly Beneficial to Your Health

Why We Think It May Reduce the Risk of ALZHEIMER’S DISEASE and Other Inflammatory Diseases, Including Atherosclerosis, Type 2 Diabetes, Ulcerative Colitis, Even Male Pattern Baldness Sandy Shaw WITHOUT PRIOR REVIEW BY DURK It has not been read or reviewed by Durk Pearson, due to considerations...

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What does it mean. Does it cause shedding?