hair today gone tomorrow
Senior Member
- Reaction score
- 1
Bryan said:hair today gone tomorrow said:oh ok, i understand now....well whats the "highest" possible SS you can attain? would that be at 2.5mg? I mean it has to plateau at some point.
It doesn't plateau at any point. It's proportional to the dose. The more you take, the higher the blood level.
At higher levels (like around 1 mg/day and above), the steady-state level is almost DIRECTLY proportional to the dose. In other words, doubling the dose approximately doubles the steady-state blood level. At lower doses (like 0.1 mg/day, for example), doubling the dose has an even GREATER effect on steady-state levels, because of dutasteride's non-linear elimination characteristics.
Ok makes sense for dutasteride blood levels...but really there would be not point in going over 2.5 mg/day because while dutasteride blood levels will keep increasing with higher dosages, dht inhibition levels plateau greatly at 2.5mg....because its just at about 100% of the alpha R II enzyme is destroyed....right?