This is long but it would mean a lot if anyone has any idea about these side effects, and could give me there opinion.
I've been using Topical Setipiprant for several months now and during this time it's absolutely made a difference in terms of itch and shedding. I've only bought from Lyphar so I'm pretty sure it's legit based on other people's experiences/lab tests.
However I've gotten some side effects, some which are normal and some I'm not sure are normal. So I'm curious if anyone else has had this. For the first month about I used normal Seti in the Swisstemples vehicle at 5% concentration. It made a difference but was greasy and disgusting on my scalp/hair. Over time I eventually got extreme daytime fatigue as well as slightly feeling it was harder to breathe. I'm almost definitely sure now this was caused by the DMSO making it go systemic, and fatigue/somnolence is listed as one of the side effects from the oral seti trial so it makes sense.
So I then bought there Salted Setipiprant and it dissolved way easier obv. I used it in Garnier Stemoxydine at 10%. It had the same efficacy as the normal Setipiprant. Then I started dermarolling with .5 mm needles before applying and it worked even better. However this made too much of it go systemic as I again had some daytime fatigue and breathlessness but not as much as with the normal seti with the swisstemples vehicle.
I also got another side effect which was weird. A little bit after applying Seti to my scalp, my urine has a really strong smell to it. It is hard to describe, it's slightly chemical but mostly smells like just really strong piss like when your dehydrated. I know it's the Setipiprant as whenever I stop applying Seti my urine smells normal. I've started and stopped multiple times to make sure and the smell always goes away in a day.
I've also recently started mixing the Stemoxydine vehicle with some DMI. Now when I apply it after dermarolling I no longer have any daytime fatigue. My piss still smells weird though. DMI supposedly makes topicals penetrate deeper, so why does this no longer give me fatigue? Since Seti supposedly leaves the body fast through urine, could the smell just be the Seti itself? Is it something to do with my liver? Does anyone know or have any theories?
So have any long time users got any of these side effects before?
@westonci @alebaba etc
Also for any longtime users using high % topical Seti (15%, 20%, 25%, 30%) Did u start at a lower percentage and then taper up? At what percentage did your shedding completely stop? How many ml do you apply per 2x a day?
Thank you to anyone who read this novel.
