Tretinoin Enhances Minoxidil Response In Androgenetic Alopecia Patients By Up-regulating Follicular

[jamesbooker1975]

Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Up-Regulating Follicular Sulfotransferase Enzymes.


The first studies done with minoxidil and tretinoin are from 1986. So no comment.
Anyway, since tretinoin is active against acne, I guess that it also work by other mechanism against baldness.

But , for people that don't respond to minoxidil, this combination is a must to try.

 

[hairDespair]

Hmm...that might explain why I've been seeing more of a response on my temple points than in the hairline. I've only just started min. I've used retin-a for like 13 years

 

[Bigbone]

Hmm...that might explain why I've been seeing more of a response on my temple points than in the hairline. I've only just started min. I've used retin-a for like 13 years

How does your skin compare to others the same age?

 

[hairDespair]

How does your skin compare to others the same age?

People say I look like 10+ years younger haha. I get it A LOT. But I also started staying out of the sun/using sunscreen around the same time

 

[jamesbooker1975]

How does your skin compare to others the same age?

I have being using since 1998 . Same here, not older than my pal of the same age. In fact, I look kind of younger than the average.

 

[Jakejr]

I have all these compounds.
Ok next time I use minoxidil I’ll rub some tretinoin in scalp first.
My scalp must be thinking what the F* is he doing now..

 

[NotInmywatch]

link to the full study

https://docdro.id/2xsN70e

 

[kiwi666]

So:
1. Needling 2mm
2. Apply tretinoin
3. Apply Minoxidil

 

[Jakejr]

Interesting...
Study says only 30/40%typically respond to minoxidil. They DO have a test to measure minoxidil response to hair called Munich Test. This test measures sulphotransferase follicular enzymatic activity.
Subjects told to use tretinoin & minoxidil on dry scalp. Tretinoin increased thickness of dermal layer. This study only lasted 5 days.
Significant increase in this sulphotransferase follicular enzymatic activity in most, not all, subjects man/woman.
So this scientific study shows an increase in this “marker” with tretinoin.
Some forum commentators say minoxidil increases the hairs androgen receptors in long run.. I don’t know, but this furthers my understanding of minoxidil.

 

[Alex Contee]

Anyone have a good source for this. Everything I see has a minimum order of a kilo.

 

[jamesbooker1975]

Anyone have a good source for this. Everything I see has a minimum order of a kilo.

Just buy the cream, apply the Rogain and then the cream.

 

[Alex Contee]

Just buy the cream, apply the Rogain and then the cream.

I’m a diffuse thinner and my hair isn’t super short

 

[Trouse]

I’ve been applying a retinol prior to minoxidil on the scalp for a while because I saw a poster here say this a while back. No idea if it’s been effective but it’s habit now I guess. Not the exact same as tretinoin but they’re pretty similar.

 

[sinusoid]

People have been talking about this for years. I don't put retinol on my scalp but I do put it on my face. In areas where the minoxidil and retinol overlap like the temple points I do feel there is increased effectiveness. In 2-3 years of hairloss treatment my temple points haven't moved at all, actually. I plan on starting tretinoin this month so it will be interesting to see what happens.

 

[kiwipilu]

on the other side tretinoin+minoxidyl once a day looks equivalent to minoxidil twice a day.
https://www.ncbi.nlm.nih.gov/pubmed/17902730
me who did not really respond well to minoxidil, maybe it's time to give this another go.

 

[igamblesowhat]

Does anyone have a recommendation for a pure tretinoin product? Or at least, the purest available? I looked at a few on Amazon and there were 2 dozen ingredients that I don't recognize and don't give a damn about tbh. I'd rather apply the purest form possible if I were to try this out on my hair (don't care about applying this to facial skin).

So, any recommendations on brands?

 

[NotInmywatch]

Does anyone have a recommendation for a pure tretinoin product? Or at least, the purest available? I looked at a few on Amazon and there were 2 dozen ingredients that I don't recognize and don't give a damn about tbh. I'd rather apply the purest form possible if I were to try this out on my hair (don't care about applying this to facial skin).

So, any recommendations on brands?

I have the same problem. commercial tretinoine sits around 0.05 % so pure tretinoine would be great

 

[Alex Contee]

I have the same problem. commercial tretinoine sits around 0.05 % so pure tretinoine would be great

You can get it directly from some companies but it’s pretty pricy (although not much is needed).

You can order from Alibaba but there is a min 1 kilo order.

 

[Badbald]

Interesting that this is another acne treatment abit like CB but through a different mechanism

Topicals this could work synergistically with

Minoxidil (obviously)
Nizoral Cream
Sandalore
CB

Wound with these and you may be on to something worth while

 

[NotInmywatch]

Interesting that this is another acne treatment abit like CB but through a different mechanism

Topicals this could work synergistically with

Minoxidil (obviously)
Nizoral Cream
Sandalore
CB

Wound with these and you may be on to something worth while

in that stack, CB is doing like 95% of the job, though.