I am offering myself to find out
I'll dose it twice a week for a month (test baseline, 1 week and at 1 month). If it remains stable and the same after one month at least we know that 0.025% could potential only inhibit 25% after 5 weeks of usage dosed twice a week. Finasteride acts during 4 days despite the short half life. Given the drug's half-life I doubt much more accumulation would occur.
Then I'll do it daily for another month and check again and back to twice a week to check for a last time.
I have no no further systemic accumulation with Topical Dutasteride at 0.1% once the cycle has been met. In fact may last DHT test came out above 300 and it was 270 before with 0.1%. It got has low as 175 with 0.5% but I mega dosed purposely to see.
I am done with Parati. I ran out of Trichosol and bought a few bottles. Got them. Insomnia, no libido, dead dick, no morning wood (it's 3am now and just woke up again after 4 hours) and anxiety after 2 applications of 0.5%. So much for Liposomes preventing systemic absorption. At least there is no brain fog. Also, it's a complete pain in the *** to apply this gel if you have long hair. It leaves it sticky for hours.
Back to 0.1% Trichosol after this. Open to try 0.25% as well.