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Topical Dutasteride Case Assessment Thread
- Thread starter FilthyFrancis
- Start date
Thank you for your enlightened argument. It is beyond my capabilities to debate at such a high standard.
Thanks for your contribution to the thread Newton. Your input is invaluable to all of us.
Now please, if you don't mind, contribute or get out. You are wasting this space with your ignorant posting.
Awesome results for 2 months.
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It might be that topical dutasteride is a good counter to persistent cases of thinning. Some people respond very well to finasteride and a reduction of their serum dht. Others need a more targeted approach to the hormones produced directly from the follicles
eeeeeee, it's a fixed price.... MORON.
If you go in once a month, 4 times a year or the suggested protocol which is 4 times on the first month they charge you the same fee
Scar tissue because of dermarolling at 2mm once a week....
Jesus Christ. IDIOT!
What clinics in Belgium?
I never needle without first putting a box of tissues within reach. I find it very annoying.
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I learned today that Minoxidilmax (producer of a.o. Essengen 6 Plus, Maxogen etc.) is now also offering a topical dutasteride, see;
It is a 0.2% topical dutasteride solution. I'm genuinely curious to hear the opinion of you guys. Are the ingredients used good?
And would applying it 1-2x a week (instead of daily) be sufficient given dutasteride's long half-life?
It is a 0.2% topical dutasteride solution. I'm genuinely curious to hear the opinion of you guys. Are the ingredients used good?
And would applying it 1-2x a week (instead of daily) be sufficient given dutasteride's long half-life?
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Steal sanics hairline
-use topical dutasteride once a week so it doesn't build up
-use topical dutasteride once a week so it doesn't build up
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I have read that if you dermaroll too often with long needles and dont give it enough time to heal and roll again before the skin had a chance to fully heal itself from the tiny wounds then yes you can cause MICRO SCARRING. jesus you are so f*****g ignorant. there are even people that say their hair gets thinner after needling on hairloss forums. im just warning my fellow balding men except for you, cause you are an a**h**.
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three days apart is too often to needle man you will cause scarring if you keep this up you need the skin to fully heal up first before you roll again.
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I never said anything about the price u idiot im saying those surgeons just wanna rip you off, they dont care about your safety, "money over safety"
therefor "money talks" which means money is more important to them than your safety.. you seem to have comprehension problems.
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Do you know the half life of a single dose? I have a intellectually intensive job and can't have brain fog (which I had on finasteride) for weeks on end. Any help on dosing for my specific situation would be great to minimize brain fog sides.
I believe that one of the most worrisome parts, regarding Dutasteride, is the huge increase to scalp Testosterone->http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.319.7620&rep=rep1&type=pdf
“Scalp testosterone levels significantly increased in all active treatment groups compared with placebo, increasing by 23%, 39%, 99%, and 222% with 0.05-, 0.1-, 0.5 and 2.5-mg dutasteride, respectively, and 23% with finasteride.”
“ Scalp DHT concentrations in the dutasteride groups were also significantly suppressed compared with placebo in a dose-related manner. As with serum DHT, the 0.1-mg dutasteride and finasteride groups showed a comparable degree of scalp DHT suppression (32% and 41%, respectively). Scalp DHT decreased by 51% with 0.5-mg dutasteride and by 79% with 2.5-mg dutasteride.”
(It's about the oral route, but I guess topical, would yield the same effect? And even if T it’s not binding as strong as DHT to the AR receptor, this huge rise is still scary. Maybe if it’s used once a week, due to the great half-life, it would be possible to avoid these spikes on scalp T.)
“Scalp testosterone levels significantly increased in all active treatment groups compared with placebo, increasing by 23%, 39%, 99%, and 222% with 0.05-, 0.1-, 0.5 and 2.5-mg dutasteride, respectively, and 23% with finasteride.”
“ Scalp DHT concentrations in the dutasteride groups were also significantly suppressed compared with placebo in a dose-related manner. As with serum DHT, the 0.1-mg dutasteride and finasteride groups showed a comparable degree of scalp DHT suppression (32% and 41%, respectively). Scalp DHT decreased by 51% with 0.5-mg dutasteride and by 79% with 2.5-mg dutasteride.”
(It's about the oral route, but I guess topical, would yield the same effect? And even if T it’s not binding as strong as DHT to the AR receptor, this huge rise is still scary. Maybe if it’s used once a week, due to the great half-life, it would be possible to avoid these spikes on scalp T.)
no reason to scare people with words like "irreversible" mate.
Duta binds to 5ar and block it till the 5ar turnover (a week more or less, but the build-up after multiple doses makes turnover not so fast due to long duta half-life) Same story for abiraterone and enzimatic turnover of CYP17A1. Apalutamide is a different story, it binds to AR and blocks androgens binding as long as u use it (with lower affinity for AR than DHT).
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Would you be able to have a study or opinion on how much of one single topical dose of dutasteride would result in sides for just a week? I am trying to get my dosing right as I cannot have prolonged sides due to work and my propensity to brain fog
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So once a week topical dutasteride is enough?
This is literally impossible to determine. Even in a large scale trial they don't test for "sides in one week". Try it for yourself and see if you get sides. If you do, stop.
Irreversible? It reverses as soon as you stop taking the drug...otherwise why would we be popping finasteride daily?