He's doing hair transplantI love you guys. Even if I dont understand the science behind all this, I am sure somebody will find the cure with the group buys here
Where is @FollicleGuardian btw? Did he get the cure and left us all alone to suffer?
I love you guys. Even if I dont understand the science behind all this, I am sure somebody will find the cure with the group buys here
Where is @FollicleGuardian btw? Did he get the cure and left us all alone to suffer?
Iirc last time you talked about twist1 in discord there was somthing preventing from us actually using it , i think it was the WNT pathway if im not wrongAnti-androgens will always be the first-line defense against hair loss. However, in prostate cancer Twist1 knockout alone was as effective as complete androgen receptor knockdown.
So you finally found it ? When you plan to start the new GB ?The lack of any good compounds to inhibit it.
Fuk me daddySo you finally found it ? When you plan to start the new GB ?
I wanna top u bbHe's doing hair transplant
Iirc last time you talked about twist1 in discord there was somthing preventing from us actually using it , i think it was the WNT pathway if im not wrong
smort. Its the only way we can buy 5+ more years of waiting for research (once again). Hopefully HMI-115 avoids the inevitable second transplant tho lolHe's doing hair transplant
Nice, thanks for the info, that indeed sounds very good, finally a new pathway where going ham might not be harmful enough (like PRL inhibitors)There is no chance that inhibiting Twist can cause cancer. Twist1 promotes tumor growth, and these two drugs were developed to treat cancer. It will only upregulate R-spondin in tissues where it is supposed to be upregulated, like the hair follicle. Even in prostate cancer RSPO is downregulated, and lower R-spondin levels are associated with lower survival rates. Twist1 activates Wnt target genes also, differentially from beta-catenin. It shifts the pathway towards EMT which promotes tumor migration.
@Admin there are some trolls here
Compound I must assume. They cant rly guarantee your solution will be stable enough for shipping esp. for a new and unknown compound you must test diferent vehiclesWill the GB be for the compound or for a ready to use topical. I’m definitely more into the later.
Do you also want it to include a person that applies it for you everyday? And perhaps additionally performs a nice massage? Like a combi deal?Will the GB be for the compound or for a ready to use topical. I’m definitely more into the later.