There is no contradiction, but I had the same question because the explanation is a little confusing on the website. The 2% is applied as a liquid, applied by dauber. He doesn't want the dauber to become contaminated and begin to smell. The 5% is a cream and applied by hand. Wash your hand. As a cream, it can provide additional benefit (purportedly) as an occlusive dressing by applying last. One more thing, if you use folligen, I like to use it last of the last because it causes the smell to cease seems to trap the rest of the stuff in a bit and keep it off my pillow etc. But that's just a personal preference.