Shiseido Hair Loss Clinical Trial To Begin
- Thread starter Swoop
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Noisette
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Hi 
Here is a new article published today "RepliCel's Cell Therapy for Pattern Baldness Proceeds to Clinical Trial Launch in Japan"
http://www.marketwired.com/press-re...trial-launch-japan-tsx-venture-rp-2144293.htm
Quote : " a clinical-stage regenerative medicine company focused on the development of autologous cell therapies, is pleased that its RCH-01 product, for the treatment of androgenetic alopecia, is now cleared by the Japanese regulatory authorities for use in a clinical research study launching now in Japan".
Here is a new article published today "RepliCel's Cell Therapy for Pattern Baldness Proceeds to Clinical Trial Launch in Japan"
http://www.marketwired.com/press-re...trial-launch-japan-tsx-venture-rp-2144293.htm
Quote : " a clinical-stage regenerative medicine company focused on the development of autologous cell therapies, is pleased that its RCH-01 product, for the treatment of androgenetic alopecia, is now cleared by the Japanese regulatory authorities for use in a clinical research study launching now in Japan".
@Swoop I respect your thoughts so that's why I want to ask you how confident you are that this treatment could be effective?
I've glanced at Replicel time and time again and Dr. Rolf Hoffman and their data have not convinced me. Them saying it was a small test dose or w.e seems like a bad excuse - they've had over 10 years to work on this.
In the 2015 interview with hellouser, all his answers seemed to lack decisiveness. He said things like "let's see", "we don't know that yet", "repeat procedure a year later/who knows?".
Further on from this, he seemed really pessimistic about cure-like treatments coming any time soon when asked at the recent gathering of hair specialists in Georgia.
Also we mention Lee Buckler a lot but I don't think he knows a lot more than all of us. He communicates well but he is not a Doctor at the end of the day.
The fee Shiseido paid for the Replicel technology was pennies for such a huge company. I think $4 mill. The cynic in me is thinking this was what Replicel were seeking all along, a big money pay-out.
Some might say that Shiseido have built a research facility so they must be serious, well if it didn't pan out they could convert it or perhaps they would continue pursuing hair research.
Swoop why are you hopeful about this?
They already did one study with this stuff and the results were poor.
Do you know something that I don't know?
Have they made fundamental changes to the treatment?
If they have not fundamentally changed the technology I don't see how they can expect good results. They already did one study and it was disappointing to say the least.
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I believe it was $400 mill, so not pennies.
And hopefully they have more data than 6 months that convinced Shiseido.
Blackber
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http://replicel.com/wp-content/uploads/2015/02/RepliCel-Fact-Sheet-Feb-2016.pdf
1st page bottom right corner. $31mil plus sales royalties and all expenses paid.
The amount of misinformation spread on these forums that is taken as gospel is staggering sometimes.
1st page bottom right corner. $31mil plus sales royalties and all expenses paid.
The amount of misinformation spread on these forums that is taken as gospel is staggering sometimes.
The $31 million are yet to be made milestone payments.
As I said, Replicel received $4 million.
http://replicel.com/replicel-and-sh...-and-exclusive-geographic-technology-license/
That's incorrect.
$4 million was paid by Shiseiso for Replicel's technology. That is chump change for a company the size of Shiseido.
To put it in context, Shiseido bought Bare Escentials for $1.7 billion in 2010.
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The deal between Shiseido and Replicel is great for the product that done only phase 1.
4kk + 31kk and royalties for product that has done only phase 1 is bad?
I think it was discussed in 10+ threads that RCH has solid science in it.
Phase 1 was only for safety and they have 5 years data that says IT IS SAFE.
Poor results? I think even trial was designed for safety it showed big potential. Majority of patients got regrowth (that means finasteride + minoxidil result only with 1 injection)
Phase 1 was ONLY 1 injection and that famous picture was shot by trichoScan. Picture of whole scalp would be meaningless because they tested RCH only on very small area (size of the biopsy area). In phase 2 they will do much more injection sites.
I have seen phase 1 biopsy (from distance) and it was very small, maybe 0.5cm2 (?)
4kk + 31kk and royalties for product that has done only phase 1 is bad?
I think it was discussed in 10+ threads that RCH has solid science in it.
Phase 1 was only for safety and they have 5 years data that says IT IS SAFE.
Poor results? I think even trial was designed for safety it showed big potential. Majority of patients got regrowth (that means finasteride + minoxidil result only with 1 injection)
Phase 1 was ONLY 1 injection and that famous picture was shot by trichoScan. Picture of whole scalp would be meaningless because they tested RCH only on very small area (size of the biopsy area). In phase 2 they will do much more injection sites.
I have seen phase 1 biopsy (from distance) and it was very small, maybe 0.5cm2 (?)
Hairismylife
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Guys who always critisize Phase 1 result, you can't read English? It's really annoying when you repeat and repeat the same point while many others have said many times that Phase 1 was just for SAFETY WITH LOW DOSE, and still it gave 10% regrowth. Please you guys can you think more rationally or read through the thread before spreading this BS point again and again? Same goes for SM 6 months result.
It's crazy how many people are so negative about replicel based on a trial for safety. It's an injection that gives PERMANENT results and can be out soon. I'm sure results will be a lot more impressive from phase II because they will try for maximum efficacy but we won't hear results for at least a year and I'm sure the negativity will continue until then
Naysayers gonna naysay right up until the day it comes out. Perhaps even longer.
I read the dose for the first study was not a low dose. I read it was a substantial dose.
Permanent results is their aim and the new cells they inject replace damaged ones and protect hair from the effects of DHT. These new cells will be DHT resistant so it will be permanent. They've also stated that the injections will make the hairs return to normal function so the 10% could increase (but they only tracked growth and thickening for 6 months so that's yet to be seen).
Also they only did ONE injection that was not substantial it was a test for safety! the second trial is multiple injections, you cannot judge efficacy off a safety trial! I don't know how many times this has to be said
Blackber
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