- Reaction score
- 14
3 month update from me on Kane’s Seti. Not too many sides at all really unnoticeable for me however it’s done literally zero for my hair . Not sure if my batch was fake as well.
Absolute tiredness, and sexual related side effects. That's why the possibility of impurities causing this would be great, because it means there is "hope." But we'll see.
fully agree. the standard makes the nmr test easier and cheaper. but still unavoidable.Nice, good job. I'm curious to the outcome.
I find the statement of that Jashonik guy quite ridiculous though: "There is no need to do NMR, FTIR etc with each sample when there is standard available".
Go e-mail top tier laboratories and see what they have to say about that.
My question: Widely reported by seti users using product from what supplier?
Actually, i don't think it's a supplier related issue.
Prostaglandin D2's role in the sleep regulation system has been fairly known since 1988, it's a a physiological regulator of sleep in mammalians' brains.
Identified as a sleep-inducing substance, so feeling tired is not uncommon, i guess taking in before going to bed should do the trick, not in the morning.But nonetheless it will definetly be a common side effect of this treatment, impurity is not related.
Prostaglandin D2 and sleep/wake regulation. - NCBI
https://www.ncbi.nlm.nih.gov/pubmed/22024172
Prostaglandin D2 and sleep--a molecular genetic approach. - NCBI
https://www.ncbi.nlm.nih.gov/pubmed/10389108
Prostaglandin D2 in sleep-wake regulation: recent progress
https://www.ncbi.nlm.nih.gov/pubmed/11843094
Prostaglandins and adenosine in the regulation of sleep
https://www.ncbi.nlm.nih.gov/pubmed/17129762
Prostaglandin D2, a cerebral sleep-inducing substance in monkeys
www.pnas.org/content/85/11/4082.full.pdf
1988, shieeeeeeetttt that's old
Yes, but what receptor ? PDG2 have many receptors, CHRT2 is just one of them
Yes, but what receptor ? PDG2 have many receptors, CHRT2 is just one of them
Dont care all pale to being baldDP2/CRTH2
Tiredness vs Sexuals Probs. Choose your field boys
IIRC, pgd2 was responsible for deep sleep. so the reason for tiredness is that u didnt get enough of deep sleep. thats why it is recommended not to take seti before bed.Actually first Kythera trial seems to point the opposite.
Setipiprant's side-effects reported in trials were: dry mouth, nausea, somnolence, hepatic enzyme elevation, and anxiety.
Quote comes from slideshow from Kythera before Allergan bought it, seems it's not sleep disorder but somnolence, so like i mentioned before, taking it before going to bed seems fair, taking it in the morning could lead to somnolence through the day aka tiredness.
Try to retrieve these slides but no luck so far, i remember side effects rate were quite low anyway
IIRC, pgd2 was responsible for deep sleep. so the reason for tiredness is that u didnt get enough of deep sleep. thats why it is recommended not to take seti before bed.
Does Seti cross the BBB?