RU58841 *can* go systemic and the side effects are very real. I was a doubter.

[linoob]

Before I even begin, I already know most of you are already going to write this thread off.

I was the exact same. Every time I came across something like this, I just thought the following:

- It's all in their head

- It's a placebo

- It must be their anxiety

- They're exaggerating

- They must be one in a million (Maybe this is true?)

If I was on the other side of the screen reading this, I would likely dismiss this thread in a heartbeat.

I'm 6'0 / 75KG / 30 years old. About a month ago I started dosing 50mg ED of RU58841 and like most of you who've experienced sides, I had very high hopes. I also wore gloves and was VERY careful.

Prior to usage, I skimmed through a few negative stories here and there, but after a couple of weeks of usage I honestly forgot about it all entirely and just went on with my life.

Where it started:

A month or so into usage, I noticed that occasionally at night or when sitting down I would feel my heart do intermittent flutters. The kind of feeling you get when it skips a bit - not pleasant at all.

The next day, I started having intermittent periods throughout the day where I would experience shortness of breath like I couldn't get enough oxygen when I breathed in.

I know what you're thinking, sounds exactly like anxiety, right? I would think the exact same thing having being told this.

The truth is, it's very similar to anxiety (the shortness of breath, that is), however, there is no anxiety present whatsoever, it's like a legitimate "Damn, I'm really not getting enough air?" type of feeling.

The other more worrisome symptoms also started that very next day, where I would have a dullish chest pain right over my heart/sternum/stomach area. This would come and go and while not overly painful, was nothing like I have ever had and felt very ominous.

Obviously, I immediately stopped all usage of the drug, however, I am still currently experiencing an uncomfortable chronic tightness of my chest/sternum area / dull ache over my sternum area / intermittent shortness of breath / sometimes backaches.

I've also noticed visible enlarged / puffy nipples (aka Gyno) which is something that simply cannot be manifested or fabricated such as the other symptoms above. If you want pictures, I will happily DM you.

I went to the hospital today out of concern, they ran basic ECG's. I also had a blood test to measure my Troponin levels as this can indicate if there has been any significant heart-related stress - also negative.

You would think this would put me at ease, but I am still relatively concerned as it's now been ~4 days without using the drug and I am still experiencing a myriad of very worrisome symptoms.

The reason I made this thread is to let you know, I'm just a normal guy like you. I'm not some academic researcher, but I did do my fair share of reading prior to treatment.

I am sure the majority of people who try RU58841 turn out just fine, but for the percentage that it goes systemic and produces negative side effects - I hear you, I believe you, it's okay.

Can anyone else who has had similar side effects to mine chime in?

I think at this point I'm just looking for some reassurance that these symptoms will eventually go away as they are nothing like I have ever experienced.

 

[jamesbooker1975]

I really don't understand the obesecion with RU. A drug NEVER TESTED IN HUMANS ! while you can use topical dutasteride, topical ketoconazole, etc. And with a simple bloodwork you can know if dutasteride is going systemic or not .
Instead of that, people go and compound a homemade in China drug, that have ZERO studies done in human . People are simple stupid.

 

[linoob]

I really don't understand the obesecion with RU. A drug NEVER TESTED IN HUMANS ! while you can use topical dutasteride, topical ketoconazole, etc. And with a simple bloodwork you can know if dutasteride is going systemic or not .
Instead of that, people go and compound a homemade in China drug, that have ZERO studies done in human . People are simple stupid.

Thanks for the constructive feedback.

 

[altsequence]

I had the same cardio symptoms your having after using 4% for maybe 1.5 months. First noticed a fluttering sensation, like if your heart was walking down the stairs and tripped down a step, then regained footing. This came on slow so at first I thought it was just anxiety induced. then it started happening more often with an accompanying paid. After quitting at least 4 months ago, got my hands on some Hawthorne supplement per the advice of some other guy who experienced the same, which seemed to help. Things are back to normal from what I can tell. The symptoms lasted way longer than I thought they should have - still had mild ones more than a month after stopping which is equally scary.

 

[linoob]

I had the same cardio symptoms your having after using 4% for maybe 1.5 months. First noticed a fluttering sensation, like if your heart was walking down the stairs and tripped down a step, then regained footing. This came on slow so at first I thought it was just anxiety induced. then it started happening more often with an accompanying paid. After quitting at least 4 months ago, got my hands on some Hawthorne supplement per the advice of some other guy who experienced the same, which seemed to help. Things are back to normal from what I can tell. The symptoms lasted way longer than I thought they should have - still had mild ones more than a month after stopping which is equally scary.

Thank you for the detailed reply and talking about your experience my man.

Any idea what the supplement was? I would love to look into it.

At this stage my symptoms do feel as though they are a little better, but I still get incredibly short of breath when walking around.

Currently I'm just resting, having plenty of water, vegetables, good foods, vitamin d supplement with K2, zinc and magnesium.

My understand is these are excellent for promoting good cardiac function.

 

[LouisSarkozy]

I had the same cardio symptoms your having after using 4% for maybe 1.5 months. First noticed a fluttering sensation, like if your heart was walking down the stairs and tripped down a step, then regained footing. This came on slow so at first I thought it was just anxiety induced. then it started happening more often with an accompanying paid. After quitting at least 4 months ago, got my hands on some Hawthorne supplement per the advice of some other guy who experienced the same, which seemed to help. Things are back to normal from what I can tell. The symptoms lasted way longer than I thought they should have - still had mild ones more than a month after stopping which is equally scary.

what supplement ? thanks

 

[altsequence]

It was a 150mg Hawthorne supplement from GNC, but any one should do. Hope it helps.

 

[linoob]

It was a 150mg Hawthorne supplement from GNC, but any one should do. Hope it helps.

I looked into this and it appears it's more so just to reduce blood pressure?

Mine is okay.. fine even.

It's more the rapid heart beat and shortness of breath.

 

[SwoopSwoop]

I've used a 1.5% solution for a few weeks and was fine. Then I used a 5% solution (50mg dose) once, 2 days after microneedling, and got pretty serious side effects: dull chest discomfort (like a weight was on in), extreme brain fog, complete ED. They mostly resolved in respectively 1, 2 and 3 days. I haven't touched RU since, I think it's risky as hell.

 

[telogen]

Been using RU in large amounts for 8 years and never experienced anything like this

 

[SwoopSwoop]

Been using RU in large amounts for 8 years and never experienced anything like this

Do you microneedle? I think in my case that was a big contributor to my systemic side effect.
Any heart problems at all? Any other anti-androgenic effects? What's your experience in general?

 

[linoob]

I've used a 1.5% solution for a few weeks and was fine. Then I used a 5% solution (50mg dose) once, 2 days after microneedling, and got pretty serious side effects: dull chest discomfort (like a weight was on in), extreme brain fog, complete ED. They mostly resolved in respectively 1, 2 and 3 days. I haven't touched RU since, I think it's risky as hell.

Indeed man.

It's scared the absolute hell out of me and been a huge eye opener. I had an echo today with a specialist.

His words were something like:

"You heart seems okay, It's pretty good, I'm not too concerned.. it's not operating / pumping at 100% capacity for someone your age so to be safe we'll take a better look at it" (I'm 30)

So I'm booked in to see him again in the not too distant future.

He said this could just be a small thing and really seemed pretty indifferent, but it still has me on edge hoping I haven't done any damage from this drug.

I will keep you all posted anyway.

 

[telogen]

Do you microneedle? I think in my case that was a big contributor to my systemic side effect.
Any heart problems at all? Any other anti-androgenic effects? What's your experience in general?

Gyno og high E symptoms on high amounts, but it resolved itself when i went from applying once to two times a day (in smaller single amounts).

 

[linoob]

Gyno og high E symptoms on high amounts, but it resolved itself when i went from applying once to two times a day (in smaller single amounts).

What was your previous dose with symptoms and what's your current dose now?

 

[linoob]

Just want to give an update to my situation incase any concerned future readers come across this thread and want to know what happened.

It's now 26/09/21. I started experiencing side effects on 15/09/21 to which they peaked around 19/09/21.

I experienced pretty significant shortness of breath for about 8 or 9 days (to the point where even sitting down and talking would have me gassed). I'll add that I did have an intermittent itchy / dry cough intermittently through the week.

This has finally started to subside as of today and I'm easily well enough to walk around, do light exercise, etc. It's barely noticeable at this point.

I also ended up having a full doppler echo done with a cardiologist who reviewed the results and said he was pretty happy with everything. He did mention that for someone my age my heart didn't seem 100% optimal, but that said wasn't overly concerned.

I am booked in again to see my cardiologist to further go over my results just to be 100% sure everything is okay.

Could the echo results be due to RU58841 usage? There's no way to know nor prove this.

All I will say as, if you're experiencing sides, I recommend stopping immediately and getting plenty of rest, water, eat healthy foods.

I also supplemented the following:

- Vitamin D
- Magnesium
- Zinc
- Vitamin C

 

[royce gracie]

Appreciate the thorough recording. I agree that cardiovascular sides are not to be fucked with and RU users should be on guard for them. I do wonder how this drug would compare to minoxidil, which has similar heart symptoms and is apparently safe enough to be OTC.

 

[linoob]

Appreciate the thorough recording. I agree that cardiovascular sides are not to be fucked with and RU users should be on guard for them. I do wonder how this drug would compare to minoxidil, which has similar heart symptoms and is apparently safe enough to be OTC.

Agreed.

People can call it what they like, placebo, anxiety, whatever.

The reality is, I'm not an anxious person. I wasn't even aware of any real negative side effects apart from chest pain.

When I experienced them, I knew fundamentally that something was majorly wrong. It just felt like blood or oxygen wasn't getting to my heart like there was a serious blockage.

When I looked up my symptoms, it goes hand in hand with that similar to a heart attack or leading up to one - Just because the doctors couldn't find evidence of any cardiac stress or muscle damage, doesn't mean I wasn't on track for one.

It's incredibly scary sitting there a week post-cessation and still experiencing major shortness of breath among other things - you fear you've done something irreparable. Fortunately, in my case, it doesn't appear to be so.

So yeah, definitely not to be fucked with, and I encourage anyone to approach this drug with caution and start and a very low dose if you are still wanting to try. (I.e 5mg twice a day / morning and night)

 

[anon082]

Sides from RU can be 100% real.
I've been using meds for almost a decade now, i was using 1mg of propecia and had mild side effects , went down to 0.5mg which decreased sides and then i added RU, after a few months on it my libido and dick just weren't working good at all. i refused to believe it for a while but then decided to quit RU and it took some time but after about 4 months things went back to normal.

Stayed on propecia for a few more years and recently when things got worse I was like what the hell let's try RU again but at a lower dosage, keep in mind I was performing sexually just fine for years, used RU at about 2% and soon enough my sh*t started getting fucked again. not to the same extent of the first time, but enough for it not being worth it as my libido just didn't feel good at all.

I'm not saying this will be the case for everyone or even the majority, but for some individuals like me RU can be really bad, I have no luck with antiandrogens

 

[Hair2Max]

Sides from RU can be 100% real.
I've been using meds for almost a decade now, i was using 1mg of propecia and had mild side effects , went down to 0.5mg which decreased sides and then i added RU, after a few months on it my libido and dick just weren't working good at all. i refused to believe it for a while but then decided to quit RU and it took some time but after about 4 months things went back to normal.

Stayed on propecia for a few more years and recently when things got worse I was like what the hell let's try RU again but at a lower dosage, keep in mind I was performing sexually just fine for years, used RU at about 2% and soon enough my sh*t started getting fucked again. not to the same extent of the first time, but enough for it not being worth it as my libido just didn't feel good at all.

I'm not saying this will be the case for everyone or even the majority, but for some individuals like me RU can be really bad, I have no luck with antiandrogens

Did you notice any results while using RU? I'm also currently using finasteride topically and thinking of adding RU as well. I haven't noticed any results from 2 months of using finasteride, minoxidil and dermaneedling. Oral finasteride does cause libido effects to me so I switched to topical one.

I also have 8 month experience of using finasteride (~5 years ago) without any noticeable results.

 

[jamesbooker1975]

Thanks for the constructive feedback.

Don't understand that it is actually constructive, is just cause you are an idiot.