Bryan said:I think the exact "concentration" in that particular regard wouldn't have much relevance. Far more important is simply the total amount of medication that you're putting on your scalp, in my opinion.
I am guessing you have little understanding of mass transport so I will stick to empirical discussion. 5% minoxidil is more effective than 2% minoxidil because of the concentration more so than because of the total exposure (or total "dose").
If you put 20 mg of drug on your scalp you do not get a dose of 20 mg. You get an exposure of 20 mg. Your dose will be dependant upon many factors, concentration being one of the most important.
Choosing a wildly underdefined scenario for simplicity, if you applied 20 mg of chemical to a membrane in a solution of 2 ml over an area 50 square inches and achive a 5 mg penetration of the membrane (due to competing rate mechanisms such as evaporation of solvent or reaction) you would expect an alternate 20 mg of chemical applied to a membrane in a solution of 1 ml over the same area of 50 square inches to have closer to double the rate of penetration and reasonably expect a penetration of closer to 10 mg than to 5 mg as in the first case.
Bryan said:I agree with your main point, but your choice of Revivogen for your example was unwise! The main ingredients in Revivogen are the fatty acids, and those aren't going to "dry out" or "crystallize" on your scalp!
Yes, I understand that this was a simple mistake on your part. I did not choose them, those products that I know little about were the topic of the post above mine and I used them as an arbitrary example, which I properly noted:
Yeddie said:I am gonig to use Reviv and spironolactone as an example, this is not to say that I know anything about how these two products should be applied or that the example would be any different with other products.