Considering the fact that a number of studies have proven that Minoxidil (Rogaine) causes a decrease in collagen production, even if it is taken topically, due to its ability to penetrate the skin barrier and go systemic, I started to look at alternatives. My attention was immediately attracted to Stemoxydine. Despite the cost and decreased efficiency, it seems to me that Stemoxydine does not cause any reduction in collagen production. I myself, have no experience with this topical treatment, and I was wondering if anyone on this forum has used this topical for a prolonged period of time? I have looked up multiple other threads that discuss Stemoxydine, but the thing is that there are simply no reviews from long-term Stemoxydine users. I would really appreciate it if someone, preferably a long-term user, could share some of their experiences with this topical.