Logically, liquid should be the superior. At least, if you're talking about Rogaine, which does not have the propylene glycol (agent that penetrates the skin) Minoxidil has. Granted, for application purposes Rogaine is easier to apply, obviously. You can diffuse it easier than you can with concentrated liquid. The other downside to the liquid is that it's easier to run down your head. Liquid minoxidil can also accidentally spill if you knock it over (sh1t happened to me once and I went ballistic). All you need however is to be careful with the thing. This reminds me of yet another con. Since it doesn't come out via pressure nozzle like Rogaine, it gets exposed to the air/moisture in air which can slightly weaken it as it gets used over the month. Chemically, liquid minoxidil is better.