Exploring The Hormonal Route. Hair=life.

sg2000

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Everything went downhills after the dht spike, my hair has never been the same till then, all points to Androgenetic Alopecia cause I have only 1 hair per shaft and different thickness (mostly miniaturized), that is what you see on Androgenetic Alopecia
how could so little dht cause this much damage ?Isnt e2 suppress all T?So where the f*** is this damn dht produced?
 

Adri23

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how could so little dht cause this much damage ?Isnt e2 suppress all T?So where the f*** is this damn dht produced?
Mostly 5ar1 prob. The thing is after a full month on dutasteride I dont see any single strand of hair growing under trichoscope, I expected at least few dots of thick hair growing but nothing but miniaturization
 

sg2000

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It's a stereotype that Asians respond well to treatment, just like it is that they don't go bald. I am an Asian who started going bald at 16 and for whom RU + Duta + Bicalutamide did not work.
lookin at adris case it seems hrt isnt the cure we all tought about
 

sg2000

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Mostly 5ar1 prob. The thing is after a full month on dutasteride I dont see any single strand of hair growing under trichoscope, I expected at least few dots of thick hair growing but nothing but miniaturization
yes but how even half 5ar1 can cause this damage? so 0.5 dutasteride is sh*t and tyhe biggest scam ever
 

Adri23

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lookin at adris case it seems hrt isnt the cure we all tought about
Well i guess im just unlucky, but im not certainly sure if estradiol alone regrow hair on many ppl tho, usually minoxidil paired with e2 + dutasteride is what causes the best regrowth in my opinion
 

Adri23

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yes but how even half 5ar1 can cause this damage? so 0.5 dutasteride is sh*t and tyhe biggest scam ever
Upregulation prob, it only happened after i got on daily bicalutamide. Thing is the upregulation never went away, I'm waiting for my december blood test to confirm my dht is really lower
 

sg2000

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Well i guess im just unlucky, but im not certainly sure if estradiol alone regrow hair on many ppl tho, usually minoxidil paired with e2 + dutasteride is what causes the best regrowth in my opinion
are you on minoxidil too?
 

losingbattle88

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Upregulation prob, it only happened after i got on daily bicalutamide. Thing is the upregulation never went away, I'm waiting for my december blood test to confirm my dht is really lower
What I dont understand is that it seems that most ppl get watery semen to some extent from finasteride or dutasteride. But on 2.5mg dutasteride my semen was unchanged or even thicker hmmm.
 

Adri23

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What I dont understand is that it seems that most ppl get watery semen to some extent from finasteride or dutasteride. But on 2.5mg dutasteride my semen was unchanged or even thicker hmmm.
Very weird. It never happened to me on dutasteride nor finasteride
 
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Adri23

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@Adri23
Is 25 mg bica eod enough to block my AR ? I'm still hairy on 4 mg estradiol bro wtf ?
Most likely yes. When I was taking 25 mg of bica EOD I had less hair on my body and even on my beard. Now that i stopped it for a month already, I am getting hairy again.

There is a study that shows it. https://www.jaad.org/article/S0190-9622(21)02738-9/fulltext

''All patients commenced bicalutamide at a dose of 10 mg. The mean dose of bicalutamide that reduced hypertrichosis was 14.4 mg (SD, 5.25 mg). The use of concurrent bicalutamide permitted an increase in the mean daily dose of minoxidil to 2.2 mg (SD, 1.67 mg) without development of hypertrichosis.''

''Oral bicalutamide appears to be beneficial in mitigating hypertrichosis caused by minoxidil in FPHL patients. Daily bicalutamide (mean dose, 14.4 mg) both reduced hypertrichosis and permitted an increase in the mean dosing of minoxidil by 0.7 mg/day without further hypertrichosis.''



As you can see per studies 14.4 mg is enough to reduce the hypertrichosis, so 25 mg EOD would be 100 mg a week and 14.4 mg ED is 100.8 mg a week so as you cant really take 14.4 mg the best bet is to use 25 mg EOD, which due to bica's half life it will be very similar than taking 14.4 mg ED.
 
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sg2000

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Even tough it doesn seem to be guaranteed im gonna give it a try and that would be my last.At least im gonna have that peace of mind that ive tried everything i can for my hair.If after 1 year im still losing ground i will stop everything!
 

sg2000

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Most likely yes. When I was taking 25 mg of bica EOD I had less hair on my body and even on my beard. Now that i stopped it for a month already, I am getting hairy again.

There is a study that shows it. https://www.jaad.org/article/S0190-9622(21)02738-9/fulltext

''All patients commenced bicalutamide at a dose of 10 mg. The mean dose of bicalutamide that reduced hypertrichosis was 14.4 mg (SD, 5.25 mg). The use of concurrent bicalutamide permitted an increase in the mean daily dose of minoxidil to 2.2 mg (SD, 1.67 mg) without development of hypertrichosis.''

''Oral bicalutamide appears to be beneficial in mitigating hypertrichosis caused by minoxidil in FPHL patients. Daily bicalutamide (mean dose, 14.4 mg) both reduced hypertrichosis and permitted an increase in the mean dosing of minoxidil by 0.7 mg/day without further hypertrichosis.''



As you can see per studies 14.4 mg is enough to reduce the hypertrichosis, so 25 mg EOD would be 100 mg a week and 14.4 mg ED is 100.8 mg a week so as you cant really take 14.4 mg the best bet is to use 25 mg EOD, which due to bica's half life it will be very similar than taking 14.4 mg ED.
let me know if you’ll ever recover with your new and consistent regimen
 

Adri23

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Even tough it doesn seem to be guaranteed im gonna give it a try and that would be my last.At least im gonna have that peace of mind that ive tried everything i can for my hair.If after 1 year im still losing ground i will stop everything!
That is what I did, the fact that I tried everything makes me less anxious of going bald
 

losingbattle88

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That is what I did, the fact that I tried everything makes me less anxious of going bald
Same here. At least I tried the standard hairloss treatments, high dose dutasteride with high dose oral min and it didnt do JACK sh*t. So I feel hrt wouldnt be much better for me. Also I reached my limit with hairloss treatments. finasteride has already given me permanent weak ejaculation from a big shooter. Hrt would mess me up permanently 100%. I wouldnt mentally handle growing tits or see my male body change in any way. I feel male and love the male body so much that I wanna lick a man all over with my tongue.
 
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Adri23

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Same here. At least I tried the standard hairloss treatments, high dose dutasteride with high dose oral min and it didnt do JACK sh*t. So I feel hrt wouldnt be much better for me. Also I reached my limit with hairloss treatments. finasteride has already given me permanent weak ejaculation from a big shooter. Hrt would mess me up permanently 100%. I wouldnt mentally handle growing tits or have see my male body change in any way. I feel male and love the male body so much that I wanna lick a man all over with my tongue.
Yeah I think it wouldn't be worth for you, the bad stuff outweights the benefits in your case, if you want to remain flat chested you rly shouldn't touch estradiol, since it will alter your nipple shape and you will start to accumulate fat on chest area 100%. It is not even a possible side effect, it is one of the very few stuff guaranted with hrt, even if you take meds like raloxifen you won't prevent chest grow 100%
 
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