Perhaps. I have to admit I am not very knowledgeable on the subject. You would have to inject it precisely at the right location though (if you go subQ it will have greater/full prospensity to go systemic, and if you inject too shallow it would still cause skin atrophy just like topical applications). Not worth it, I would say.
My E level never drops below 200 pg / ml. Is it unhealthy? Please tell us more about this if you have time. On the other hand, without the use of CPA, this is the only way to suppress T to the female level, so I would not say that we have a choice.
I am not a doctor, so I cannot give you advise about anything health related. I do know that E2 is dose-dependently carcinogenic, which would suggest we try to minimize systemic concentrations. However, E2 also has many good functions: for example, it increases HDL and lowers LDL; it is neuroprotective; it stimulates collagen production in the skin; good for hair etc. Hence, the healthiest option would be to stay within the reference range. If you are female (or want to mimic the hormonal profile of a young female) this reference range fluctuates over the course of a month as we all know. During ovulation, E2 levels peak (median) at around 200 pg/mL. During follicular phase, E2 levels very much resemble that of males: constant concentrations of around 50 pg/mL. Even if we would integrate the curve over the whole month (the so-called area under the curve, AUC), it would be well shy of 100 pg/mL. That should give you some background information, but I encourage you to do your own research.
I could be wrong, but I thought RU 58841 was his main hairloss treatment (he may not be on it right now though). He even said he was a hyper responder to it, but anyway he does some great videos, he's literally a guinea pig for experimental hormonal drugs.
You’re right, it has been around for awhile. I guess what I meant is that more people seem to be using and the good results are getting more publicity as of late.
I already take T, as in TRT. It is pretty good, but I would not advise it unless you are truly primary hypogonadal. DHT is not even correlated with T levels (within physiological ranges). Of course, T is mildly androgenic as well, that is why I am using a topical regimen in conjunction to oral dutasteride. I think people on 5ARI's need to make sure that their T levels are adequately high. In my opinion, you cannot crush your DHT, walk around with low T and expect to function decently. You need to have adequate androgenic activity, which must come from T if you are on dutasteride.
If prolactin induces hairloss to the degree that androgens can, I wouldn't think CPA would be of the benefit it often is for hair, as it spikes prolactin pretty substantially
You are right, I stand corrected. I do think prolactin is heavily involved, but in deed not to the same degree as androgens.
This was incredibly informative for me. Ive been considering TRT. Im 39 years old and was sucked into the BS of low T by the snake oil T Clinics. My levels were normal for my age, but was told I need to have levels that I had when I was 20. The funny thing, I feel great and probably don’t need supplemental T. Im sticking to a healthy diet, working out, going to bed at a reasonable time and reading more often. Im not hypogonadal, Ill pass.
whats up?
Love that name lol
I hooked up Cabergoline (a D2-dopamine receptor stimulator) to my regimen 38 days ago and so far I am not seeing any results. I will give this remedy 3 months.
autogynephilia?
Effective Testosterone Suppression for Prostate Cancer: Is There a Best Castration Therapy?
Achieving and maintaining effective suppression of serum testosterone levels in men treated with androgen ablation is one of the essential strategies in the management of prostate cancer. Historically, a serum testosterone below 50 ng/dL was considered ...www.ncbi.nlm.nih.gov
Hair growth is provided by a decrease in the T level to the castration level and an increase in the E level
T levels below 50 ng / dl are normal, but the ideal level is less than 20 ng / dl, this corresponds to castration levels and affects prostate cancer outcomes. Thus, we need to reduce T as much as possible. To do this, our E levels must be at least 250-300 ng / dL
It is not advisable to raise estradiol levels above 700 pg / ml, because in this case SHBG will go crazy, the level of free estradiol will decrease. This reduces the effectiveness of HRT. Therefore, "one cannot be mistaken in the big direction" is not quite a true statement. Ideal E levels are in the 300-700 pg / ml range, SHBG levels below 115. But because the main thing is to lower the T level to the castration level, then the error in the big direction is not as critical as in the lower one, and you will still get the result
If you do injections of Enanthate every 2 weeks with a minimum of 300 pg / ml on the last day, then according to my calculations, the peak level is around 1500 pg / ml, which is a lot. If injections are done once a week, then the peak level at the same minimum does not exceed 700 ng / dl. Therefore, I will consider giving injections once a week.
The Ikarus T level was above 100 ng / dl and the E level was 195 pg / ml. These are poor numbers and this could be one of the reasons why he was unable to restore the hairline.
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Correct.