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Oh! I am really sorry... I would not do it again Please forgive me President Putin.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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Another day another hair, Haha.
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Did you check your testosterone level? I was wondering if your hpta axis bounced back or not.
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happy to see you with this masculine face and beautiful hair
don't even think about HRT...
i think you can keep your hair with 12.5mg/d CPA plus finasteride 1mg/d without losing your masculinity
don't put your self in estradiol or high dose CPA
don't kill yourself I have been looking for some good and working medicine for my hair lately.. What do you guys think is the best option? I like some from virtual pharmacy here, for example. But maybe you can recommend more? It would be really cool!
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I tried it, and it made my pituitary glands to shut down. I had to do an aggressive PCT to restore my natural testosterone.
Estrogel will still lower T levels
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Definitely, I saw a huge improvement in my hair, but at what cost?
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How much Estrogen did you use in your topical?
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2.5 mg, and I was also on spironolactone at that time.
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Okay so it's like been on hrt basically. No wonder.
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But even if you apply 0.75 mg, it will down-regulate your hpta axis.
Could someone please explain to me, if the possibility of the partial agonist effects of SAAs like CPA/spironolactone, it is capable of making the things worse? Reading older threads, some members mentioned that is somehow fifty-fifty chance, and I believe it's making sense since Testo/DHT it will still do damage. Although, as long as I have been looking for, the majority gets very good results with CPA/spironolactone without the adverse effects of the partial agonist on the AR. So, how much should someone need to take that under consideration?
**Directly from Wikipedia: Spironolactone, similarly to other steroidal antiandrogens such as cyproterone acetate, is actually not a pure, or silent, antagonist of the AR, but rather is a weak partial agonist with the capacity for both antagonistic and agonistic effects. However, in the presence of sufficiently high levels of potent full agonists like testosterone and DHT (the cases in which spironolactone is usually used even with regards to the "lower" relative levels present in females), spironolactone will behave more similarly to a pure antagonist. Nonetheless, there may still be a potential for spironolactone to produce androgenic effects in the body at sufficiently high dosages and/or in those with very low endogenous androgen concentrations.
Thank you very much in advance.
**Directly from Wikipedia: Spironolactone, similarly to other steroidal antiandrogens such as cyproterone acetate, is actually not a pure, or silent, antagonist of the AR, but rather is a weak partial agonist with the capacity for both antagonistic and agonistic effects. However, in the presence of sufficiently high levels of potent full agonists like testosterone and DHT (the cases in which spironolactone is usually used even with regards to the "lower" relative levels present in females), spironolactone will behave more similarly to a pure antagonist. Nonetheless, there may still be a potential for spironolactone to produce androgenic effects in the body at sufficiently high dosages and/or in those with very low endogenous androgen concentrations.
Thank you very much in advance.
15mg is too much, been there, done that, higher dosages don't really give better results. You are going to be taking it for the rest of your life, be gentle on your heart.
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I don't have much information about spironolactone but if you use cpa 12.5mg/d, due to its potent antigonadotropic effect it will lower your T levels by 70% and its pretty enough to maintain a good hair, by the way, at such low doses, it wont have any antagonist or agonist effects... I have been on cpa 12.5mg/d plus finasteride 2mg/d (1mg day and 1mg night) for 20 days and its working well... And remember that you should periodically check you liver enzymes while you're on cpa
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It means the CPA is suppressing your hpta axis. Fat redistribution will happen for sure.
@ali.talebi1994 So we can “confirm” that at a dose of 12.5mg that you are taking , we don’t have to worry of CPA acting like a partial agonist ? (actually is the dose that many are taking and see results) That’s what I am thinking as well, maybe higher doses will cause the agonist effect. Thank you very much for your previous response.